| Knoll Capital Management, LLC |
| 2.72% | 3.57% | #1 | $4.7M | 1.2M | $6.7M | 630,915 | +581,042+92.10% | Add |
| BlackRock, Inc. |
| <0.01% | <0.01% | #29 | $3.0M | 766,005 | $540,882 | 50,597 | +715,408+1,413.93% | Add |
| Caption Management, LLC |
| 0.01% | — | #4 | $2.3M | 583,800 | $0 | 0 | +583,800 | New Buy |
| VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #28 | $2.2M | 572,151 | $5.5M | 518,638 | +53,513+10.32% | Add |
| Ikarian Capital, LLC |
| 0.13% | — | #2 | $1.2M | 314,200 | $0 | 0 | +314,200 | New Buy |
| GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #23 | $1.2M | 311,354 | $1.4M | 135,164 | +176,190+130.35% | Add |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #18 | $1.1M | 271,500 | $4.0M | 373,804 | -102,304-27.37% | Reduce |
| DIADEMA PARTNERS LP |
| 0.1% | — | #3 | $829,311 | 212,100 | $0 | 0 | +212,100 | New Buy |
| TORONTO DOMINION BANK |
| <0.01% | — | #10 | $782,000 | 200,000 | $0 | 0 | +200,000 | New Buy |
| JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #25 | $727,260 | 186,000 | $1.2M | 115,600 | +70,400+60.90% | Add |
| STATE STREET CORP |
| <0.01% | <0.01% | #34 | $701,532 | 179,420 | $541,128 | 50,620 | +128,800+254.44% | Add |
| CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #22 | $583,372 | 149,200 | $834,654 | 78,078 | +71,122+91.09% | Add |
| NORTHERN TRUST CORP |
| <0.01% | <0.01% | #26 | $508,933 | 130,162 | $638,556 | 59,734 | +70,428+117.90% | Add |
| BOOTHBAY FUND MANAGEMENT, LLC |
| <0.01% | — | #5 | $373,366 | 95,490 | $0 | 0 | +95,490 | New Buy |
| VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | — | #41 | $347,619 | 88,905 | $0 | 0 | +88,905 | New Buy |
| VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #19 | $344,322 | 88,062 | $739,630 | 69,189 | +18,873+27.28% | Add |
| ALLIANCEBERNSTEIN L.P. |
| <0.01% | — | #17 | $317,805 | 81,280 | $0 | 0 | +81,280 | New Buy |
| UBS Group AG |
| <0.01% | <0.01% | #35 | $158,039 | 40,419 | $360,991 | 33,769 | +6,650+19.69% | Add |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | — | #38 | $123,970 | 31,706 | $0 | 0 | +31,706 | New Buy |
| SIMPLEX TRADING, LLC |
| <0.01% | <0.01% | #24 | $100,096 | 25,600 | $230,904 | 21,600 | +4,000+18.52% | Add |
| MORGAN STANLEY |
| <0.01% | <0.01% | #48 | $99,885 | 25,546 | $16,804 | 1,536 | +24,010+1,563.15% | Add |
| Leonteq Securities AG |
| <0.01% | — | #7 | $78,200 | 20,000 | $0 | 0 | +20,000 | New Buy |
| Nuveen, LLC |
| <0.01% | — | #37 | $69,942 | 17,888 | $0 | 0 | +17,888 | New Buy |
| CITIGROUP INC |
| <0.01% | — | #33 | $69,309 | 17,726 | $0 | 0 | +17,726 | New Buy |
| Bank of New York Mellon Corp |
| <0.01% | — | #45 | $62,107 | 15,884 | $0 | 0 | +15,884 | New Buy |
| NEW YORK STATE COMMON RETIREMENT FUND |
| <0.01% | — | #20 | $55,522 | 14,200 | $0 | 0 | +14,200 | New Buy |
| MEYER HANDELMAN CO |
| <0.01% | <0.01% | #9 | $54,345 | 13,899 | $148,580 | 13,899 | 00.00% | Unchanged |
| HighTower Advisors, LLC |
| <0.01% | <0.01% | #27 | $53,434 | 13,666 | $119,365 | 11,166 | +2,500+22.39% | Add |
| RAYMOND JAMES FINANCIAL INC |
| <0.01% | <0.01% | #43 | $49,735 | 12,720 | $118,659 | 11,100 | +1,620+14.59% | Add |
| DEUTSCHE BANK AG\ |
| <0.01% | — | #42 | $49,469 | 12,652 | $0 | 0 | +12,652 | New Buy |
| WELLS FARGO & COMPANY/MN |
| <0.01% | — | #47 | $46,228 | 11,823 | $0 | 0 | +11,823 | New Buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC |
| <0.01% | — | #21 | $41,663 | 11,972 | $0 | 0 | +11,972 | New Buy |
| PRICE T ROWE ASSOCIATES INC /MD/ |
| <0.01% | — | #49 | $41,391 | 10,586 | $0 | 0 | +10,586 | New Buy |
| HB Wealth Management, LLC |
| <0.01% | <0.01% | #14 | $40,910 | 10,463 | $111,849 | 10,463 | 00.00% | Unchanged |
| Summit Financial, LLC |
| <0.01% | <0.01% | #13 | $39,120 | 10,005 | $107,007 | 10,010 | -5-0.05% | Reduce |
| &PARTNERS |
| <0.01% | <0.01% | #15 | $39,100 | 10,000 | $106,900 | 10,000 | 00.00% | Unchanged |
| MOODY LYNN LIEBERSON & WALKER, LLC |
| <0.01% | 0.01% | #8 | $39,100 | 10,000 | $106,900 | 10,000 | 00.00% | Unchanged |
| Mayflower Financial Advisors, LLC |
| <0.01% | 0.01% | #6 | $39,100 | 10,000 | $106,900 | 10,000 | 00.00% | Unchanged |
| RHUMBLINE ADVISERS |
| <0.01% | — | #36 | $26,119 | 6,681 | $0 | 0 | +6,681 | New Buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
| <0.01% | — | #32 | $23,331 | 5,967 | $0 | 0 | +5,967 | New Buy |
| JPMORGAN CHASE & CO |
| <0.01% | — | #54 | $21,488 | 5,372 | $0 | 0 | +5,372 | New Buy |
| Tower Research Capital LLC (TRC) |
| <0.01% | <0.01% | #12 | $20,668 | 5,286 | $11 | 1 | +5,285+528,500.00% | Add |
| Vanguard Global Advisers, LLC |
| <0.01% | <0.01% | #46 | $17,267 | 4,416 | $47,207 | 4,416 | 00.00% | Unchanged |
| MERCER GLOBAL ADVISORS INC /ADV |
| <0.01% | — | #40 | $12,551 | 3,210 | $0 | 0 | +3,210 | New Buy |
| GROUP ONE TRADING LLC |
| <0.01% | — | #44 | $8,211 | 2,100 | $0 | 0 | +2,100 | New Buy |
| BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #50 | $8,102 | 2,072 | $67,817 | 6,344 | -4,272-67.34% | Reduce |
| Steward Partners Investment Advisory, LLC |
| <0.01% | <0.01% | #30 | $7,910 | 2,023 | $21,626 | 2,023 | 00.00% | Unchanged |
| BARCLAYS PLC |
| <0.01% | — | #53 | $6,944 | 1,776 | $0 | 0 | +1,776 | New Buy |
| Legal & General Group Plc |
| <0.01% | — | #55 | $5,212 | 1,333 | $0 | 0 | +1,333 | New Buy |
| Ameritas Investment Partners, Inc. |
| <0.01% | — | #16 | $4,598 | 1,176 | $0 | 0 | +1,176 | New Buy |
