| GordonMD Global Investments LP |
| 11.95% | 4.19% | #1 | $30.2M | 10.0M | $6.0M | 4.1M | +5.9M+143.21% | Add |
| PFIZER INC |
| 11.43% | 3.86% | #2 | $19.5M | 7.0M | $9.2M | 7.0M | 00.00% | Unchanged |
| Laurion Capital Management LP |
| 0.38% | 0.32% | #5 | $14.8M | 4.9M | $7.3M | 5.0M | -96,445-1.93% | Reduce |
| VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #41 | $6.2M | 2.1M | $3.0M | 2.0M | +42,487+2.09% | Add |
| Atle Fund Management AB |
| 0.78% | 0.52% | #3 | $2.9M | 966,459 | $1.6M | 197,036 | +769,423+390.50% | Add |
| BlackRock, Inc. |
| <0.01% | <0.01% | #56 | $2.6M | 867,934 | $1.2M | 788,839 | +79,095+10.03% | Add |
| Palo Alto Investors LP |
| 0.38% | 0.23% | #4 | $2.6M | 864,277 | $1.5M | 1.0M | -146,233-14.47% | Reduce |
| MARSHALL WACE, LLP |
| <0.01% | <0.01% | #25 | $2.5M | 830,544 | $517,448 | 354,417 | +476,127+134.34% | Add |
| RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #23 | $2.3M | 772,232 | $1.3M | 888,680 | -116,448-13.10% | Reduce |
| GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #43 | $1.8M | 591,849 | $873,815 | 598,121 | -6,272-1.05% | Reduce |
| Woodline Partners LP |
| <0.01% | — | #17 | $1.6M | 523,999 | $0 | 0 | +523,999 | New Buy |
| 683 Capital Management, LLC |
| 0.07% | 0.07% | #9 | $1.4M | 459,367 | $1.3M | 896,263 | -436,896-48.75% | Reduce |
| JACOBS LEVY EQUITY MANAGEMENT, INC |
| <0.01% | <0.01% | #18 | $1.3M | 428,606 | $673,056 | 460,997 | -32,391-7.03% | Reduce |
| DIADEMA PARTNERS LP |
| 0.14% | — | #6 | $1.2M | 388,200 | $0 | 0 | +388,200 | New Buy |
| JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #45 | $1.1M | 363,790 | $481,740 | 329,959 | +33,831+10.25% | Add |
| Longaeva Partners L.P. |
| 0.02% | 0.03% | #13 | $1.1M | 353,582 | $734,692 | 503,214 | -149,632-29.74% | Reduce |
| Decheng Capital LLC |
| 0.13% | 0.07% | #7 | $983,698 | 326,810 | $477,143 | 326,810 | 00.00% | Unchanged |
| VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #36 | $911,988 | 302,986 | $439,310 | 300,897 | +2,089+0.69% | Add |
| STATE STREET CORP |
| <0.01% | <0.01% | #62 | $748,999 | 248,837 | $363,302 | 248,837 | 00.00% | Unchanged |
| MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #35 | $701,342 | 233,004 | $580,533 | 397,625 | -164,621-41.40% | Reduce |
| UBS Group AG |
| <0.01% | <0.01% | #52 | $467,203 | 155,217 | $371,021 | 254,124 | -98,907-38.92% | Reduce |
| Bank of New York Mellon Corp |
| <0.01% | <0.01% | #50 | $403,328 | 133,996 | $195,634 | 133,996 | 00.00% | Unchanged |
| ACADIAN ASSET MANAGEMENT LLC |
| <0.01% | <0.01% | #31 | $381,647 | 126,793 | $209,000 | 144,256 | -17,463-12.11% | Reduce |
| NORTHERN TRUST CORP |
| <0.01% | <0.01% | #54 | $373,117 | 123,959 | $148,844 | 101,948 | +22,011+21.59% | Add |
| NewEdge Wealth, LLC |
| <0.01% | <0.01% | #22 | $349,178 | 116,006 | $169,369 | 116,006 | 00.00% | Unchanged |
| XTX Topco Ltd |
| <0.01% | 0.01% | #20 | $333,926 | 110,939 | $292,140 | 200,096 | -89,157-44.56% | Reduce |
| TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #37 | $252,723 | 83,961 | $107,018 | 73,300 | +10,661+14.54% | Add |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #21 | $244,593 | 81,260 | $118,640 | 81,260 | 00.00% | Unchanged |
| BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #65 | $242,197 | 80,464 | $24,538 | 16,807 | +63,657+378.75% | Add |
| STIFEL FINANCIAL CORP |
| <0.01% | <0.01% | #38 | $212,015 | 70,437 | $73,784 | 50,537 | +19,900+39.38% | Add |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #66 | $195,951 | 65,100 | $121,911 | 83,501 | -18,401-22.04% | Reduce |
| CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #63 | $186,671 | 62,017 | $187,390 | 128,349 | -66,332-51.68% | Reduce |
| Cable Car Capital, LP |
| 0.06% | 0.03% | #10 | $184,818 | 61,606 | $89,945 | 61,606 | 00.00% | Unchanged |
| MYDA Advisors LLC |
| 0.02% | — | #14 | $150,500 | 50,000 | $0 | 0 | +50,000 | New Buy |
| Qube Research & Technologies Ltd |
| <0.01% | <0.01% | #40 | $150,295 | 49,932 | $16,478 | 11,286 | +38,646+342.42% | Add |
| UNIVERSITY OF CHICAGO |
| 0.03% | 0.02% | #11 | $146,680 | 48,731 | $71,147 | 48,731 | 00.00% | Unchanged |
| Quadrature Capital Ltd |
| <0.01% | — | #28 | $141,672 | 47,067 | $0 | 0 | +47,067 | New Buy |
| GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #70 | $138,159 | 45,900 | $68,503 | 46,920 | -1,020-2.17% | Reduce |
| Verdad Advisers, LP |
| 0.13% | — | #8 | $135,146 | 44,899 | $0 | 0 | +44,899 | New Buy |
| LPL Financial LLC |
| <0.01% | <0.01% | #61 | $131,098 | 43,554 | $48,989 | 33,554 | +10,000+29.80% | Add |
| COMMONWEALTH EQUITY SERVICES, LLC |
| <0.01% | <0.01% | #39 | $127,790 | 42,455 | $50,740 | 34,755 | +7,700+22.16% | Add |
| J. Derek Lewis & Associates Inc. |
| 0.02% | 0.01% | #12 | $126,420 | 42,000 | $62,780 | 43,000 | -1,000-2.33% | Reduce |
| CITIGROUP INC |
| <0.01% | <0.01% | #57 | $114,997 | 38,205 | $2,540 | 1,740 | +36,465+2,095.69% | Add |
| SIMPLEX TRADING, LLC |
| <0.01% | <0.01% | #47 | $114,085 | 37,902 | $369 | 253 | +37,649+14,881.03% | Add |
| Point72 Asset Management, L.P. |
| <0.01% | <0.01% | #42 | $111,647 | 37,092 | $46,729 | 32,006 | +5,086+15.89% | Add |
| Walleye Capital LLC |
| <0.01% | — | #33 | $110,702 | 36,778 | $0 | 0 | +36,778 | New Buy |
| DIMENSIONAL FUND ADVISORS LP |
| <0.01% | <0.01% | #64 | $108,887 | 36,175 | $37,832 | 25,912 | +10,263+39.61% | Add |
| MORGAN STANLEY |
| <0.01% | <0.01% | #73 | $100,679 | 33,448 | $236,667 | 106,607 | -73,159-68.62% | Reduce |
| MACKENZIE FINANCIAL CORP |
| <0.01% | — | #46 | $79,292 | 26,343 | $0 | 0 | +26,343 | New Buy |
| Cetera Investment Advisers |
| <0.01% | <0.01% | #48 | $75,250 | 25,000 | $39,800 | 27,260 | -2,260-8.29% | Reduce |
