| Knoll Capital Management, LLC |
| 6.69% | 4.9% | #1 | $11.7M | 5.5M | $9.3M | 5.5M | 00.00% | Unchanged |
| AQR CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #20 | $8.0M | 3.8M | $4.8M | 2.8M | +921,683+32.57% | Add |
| KINGDON CAPITAL MANAGEMENT, L.L.C. |
| 0.58% | 0.4% | #2 | $5.6M | 2.7M | $3.6M | 2.2M | +500,000+23.23% | Add |
| VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #69 | $5.0M | 2.4M | $4.0M | 2.4M | -1,946-0.08% | Reduce |
| D. E. Shaw & Co., Inc. |
| <0.01% | <0.01% | #29 | $4.1M | 1.9M | $2.4M | 1.4M | +536,348+38.20% | Add |
| MARSHALL WACE, LLP |
| <0.01% | <0.01% | #25 | $3.2M | 1.5M | $219,181 | 129,693 | +1.4M+1,061.95% | Add |
| 683 Capital Management, LLC |
| 0.15% | 0.13% | #4 | $3.1M | 1.5M | $2.5M | 1.5M | -50,000-3.33% | Reduce |
| JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #49 | $3.0M | 1.4M | $1.9M | 1.1M | +255,424+22.39% | Add |
| ARDSLEY ADVISORY PARTNERS LP |
| 0.28% | 0.27% | #3 | $2.7M | 1.3M | $2.1M | 1.3M | +25,000+2.00% | Add |
| BlackRock, Inc. |
| <0.01% | <0.01% | #85 | $2.7M | 1.3M | $6.4M | 3.8M | -2.5M-66.60% | Reduce |
| Qube Research & Technologies Ltd |
| <0.01% | <0.01% | #26 | $2.4M | 1.1M | $147,162 | 87,078 | +1.0M+1,196.31% | Add |
| ACADIAN ASSET MANAGEMENT LLC |
| <0.01% | <0.01% | #22 | $2.3M | 1.1M | $1.4M | 858,288 | +205,505+23.94% | Add |
| RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #24 | $1.9M | 882,000 | $1.5M | 863,187 | +18,813+2.18% | Add |
| VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #74 | $1.7M | 794,863 | $1.4M | 807,778 | -12,915-1.60% | Reduce |
| GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #63 | $1.5M | 725,444 | $917,917 | 543,146 | +182,298+33.56% | Add |
| JACOBS LEVY EQUITY MANAGEMENT, INC |
| <0.01% | 0.01% | #14 | $1.4M | 646,840 | $1.3M | 796,816 | -149,976-18.82% | Reduce |
| MORGAN STANLEY |
| <0.01% | <0.01% | #77 | $1.3M | 608,321 | $5.7M | 1.1M | -474,998-43.85% | Reduce |
| GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #78 | $1.3M | 596,029 | $2.1M | 1.3M | -655,623-52.38% | Reduce |
| CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #64 | $1.2M | 542,744 | $704,460 | 416,840 | +125,904+30.20% | Add |
| DIMENSIONAL FUND ADVISORS LP |
| <0.01% | <0.01% | #52 | $1.1M | 529,083 | $1.1M | 624,170 | -95,087-15.23% | Reduce |
| GSA CAPITAL PARTNERS LLP |
| 0.06% | 0.03% | #6 | $1.0M | 472,564 | $418,000 | 247,194 | +225,370+91.17% | Add |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP |
| <0.01% | — | #43 | $897,109 | 421,178 | $0 | 0 | +421,178 | New Buy |
| MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #48 | $767,546 | 360,350 | $1.7M | 995,243 | -634,893-63.79% | Reduce |
| UBS Group AG |
| <0.01% | <0.01% | #73 | $643,132 | 301,940 | $908,492 | 537,569 | -235,629-43.83% | Reduce |
| VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #62 | $635,255 | 298,242 | $572,269 | 338,621 | -40,379-11.92% | Reduce |
| XTX Topco Ltd |
| 0.01% | <0.01% | #10 | $542,675 | 254,777 | $127,031 | 75,166 | +179,611+238.95% | Add |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #84 | $515,669 | 242,098 | $1.1M | 622,342 | -380,244-61.10% | Reduce |
| STATE STREET CORP |
| <0.01% | <0.01% | #97 | $497,939 | 233,774 | $1.9M | 1.1M | -890,936-79.21% | Reduce |
| WOODSTOCK CORP |
| 0.04% | 0.04% | #8 | $450,818 | 266,756 | $450,818 | 266,756 | 00.00% | Unchanged |
| IEQ CAPITAL, LLC |
| <0.01% | <0.01% | #28 | $440,043 | 206,593 | $450,415 | 266,518 | -59,925-22.48% | Reduce |
| CANTOR FITZGERALD, L. P. |
| <0.01% | — | #15 | $426,000 | 200,000 | $0 | 0 | +200,000 | New Buy |
| Caption Management, LLC |
| <0.01% | <0.01% | #31 | $351,450 | 165,000 | $278,850 | 165,000 | 00.00% | Unchanged |
| WELLS FARGO & COMPANY/MN |
| <0.01% | <0.01% | #79 | $345,776 | 162,336 | $320,643 | 189,729 | -27,393-14.44% | Reduce |
| Invesco Ltd. |
| <0.01% | <0.01% | #92 | $339,820 | 159,540 | $286,790 | 169,698 | -10,158-5.99% | Reduce |
| BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #58 | $334,938 | 157,248 | $50,387 | 29,815 | +127,433+427.41% | Add |
| Palo Alto Investors LP |
| 0.05% | 0.04% | #7 | $331,660 | 155,709 | $263,148 | 155,709 | 00.00% | Unchanged |
| Point72 Asset Management, L.P. |
| <0.01% | — | #44 | $328,889 | 154,408 | $0 | 0 | +154,408 | New Buy |
| Connor, Clark & Lunn Investment Management Ltd. |
| <0.01% | — | #38 | $328,642 | 154,292 | $0 | 0 | +154,292 | New Buy |
| Man Group plc |
| <0.01% | — | #40 | $325,279 | 152,713 | $0 | 0 | +152,713 | New Buy |
| Jain Global LLC |
| <0.01% | — | #33 | $280,099 | 131,502 | $0 | 0 | +131,502 | New Buy |
| TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #54 | $272,318 | 127,849 | $377,778 | 223,537 | -95,688-42.81% | Reduce |
| NORTHERN TRUST CORP |
| <0.01% | <0.01% | #91 | $231,932 | 108,888 | $633,433 | 374,812 | -265,924-70.95% | Reduce |
| JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #98 | $224,635 | 109,578 | $38,906 | 23,158 | +86,420+373.18% | Add |
| KENNEDY CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #16 | $208,156 | 97,726 | $162,007 | 95,862 | +1,864+1.94% | Add |
| CANADA PENSION PLAN INVESTMENT BOARD |
| <0.01% | <0.01% | #67 | $200,859 | 94,300 | $80,106 | 47,400 | +46,900+98.95% | Add |
| Squarepoint Ops LLC |
| <0.01% | — | #50 | $200,322 | 94,048 | $0 | 0 | +94,048 | New Buy |
| GROUP ONE TRADING LLC |
| <0.01% | <0.01% | #47 | $194,256 | 91,200 | $197,223 | 116,700 | -25,500-21.85% | Reduce |
| Russell Investments Group, Ltd. |
| <0.01% | <0.01% | #61 | $192,450 | 90,353 | $142,466 | 84,300 | +6,053+7.18% | Add |
| Mariner, LLC |
| <0.01% | <0.01% | #53 | $192,367 | 90,339 | $155,260 | 91,870 | -1,531-1.67% | Reduce |
| ROYAL BANK OF CANADA |
| <0.01% | <0.01% | #94 | $170,000 | 79,783 | $2,000 | 1,368 | +78,415+5,732.09% | Add |
