| BlackRock, Inc. |
| <0.01% | <0.01% | #55 | $32.4M | 9.5M | $22.3M | 5.3M | +4.1M+77.51% | Add |
| TCG Crossover Management, LLC |
| 0.65% | 0.94% | #8 | $27.0M | 7.9M | $33.0M | 7.9M | 00.00% | Unchanged |
| Commodore Capital LP |
| 1.29% | 1.53% | #6 | $21.6M | 6.3M | $26.4M | 6.3M | 00.00% | Unchanged |
| Avidity Partners Management LP |
| 3.44% | 5.11% | #1 | $21.5M | 6.3M | $25.2M | 6.0M | +250,000+4.13% | Add |
| STATE STREET CORP |
| <0.01% | <0.01% | #52 | $20.6M | 6.1M | $13.1M | 3.1M | +2.9M+93.18% | Add |
| MILLENNIUM MANAGEMENT LLC |
| 0.01% | 0.01% | #27 | $16.7M | 4.9M | $16.9M | 4.0M | +865,215+21.38% | Add |
| VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #62 | $15.1M | 4.4M | $18.3M | 4.4M | +57,616+1.32% | Add |
| Affinity Asset Advisors, LLC |
| 0.65% | 0.68% | #7 | $14.4M | 4.2M | $13.2M | 3.2M | +1.1M+33.18% | Add |
| CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #34 | $13.0M | 3.8M | $15.2M | 3.6M | +165,535+4.55% | Add |
| Spruce Street Capital LP |
| 2.47% | 2.63% | #4 | $12.6M | 3.7M | $11.0M | 2.6M | +1.1M+40.61% | Add |
| BALYASNY ASSET MANAGEMENT L.P. |
| 0.01% | 0.02% | #24 | $11.3M | 3.3M | $12.5M | 3.0M | +325,764+10.88% | Add |
| GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #56 | $8.4M | 2.5M | $7.4M | 1.8M | +691,713+39.15% | Add |
| Nantahala Capital Management, LLC |
| 0.26% | — | #9 | $7.9M | 2.3M | $0 | 0 | +2.3M | New Buy |
| MORGAN STANLEY |
| <0.01% | <0.01% | #61 | $6.5M | 1.9M | $9.5M | 2.8M | -848,311-30.73% | Reduce |
| GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #54 | $5.9M | 1.7M | $5.2M | 1.2M | +491,262+39.56% | Add |
| Nicholson Wealth Management Group, LLC |
| 3.25% | 3.93% | #3 | $5.5M | 1.6M | $6.8M | 1.6M | +1,000+0.06% | Add |
| TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #29 | $5.3M | 1.6M | $4.2M | 1.0M | +552,977+55.11% | Add |
| ADAR1 Capital Management, LLC |
| 0.19% | 0.18% | #10 | $4.1M | 1.2M | $3.1M | 749,335 | +460,782+61.49% | Add |
| VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #75 | $3.7M | 1.1M | $3.1M | 752,033 | +335,734+44.64% | Add |
| DIMENSIONAL FUND ADVISORS LP |
| <0.01% | <0.01% | #50 | $3.7M | 1.1M | $1.9M | 450,097 | +623,974+138.63% | Add |
| Yu Fan |
| 3.33% | 4.54% | #2 | $3.6M | 1.1M | $4.4M | 1.1M | 00.00% | Unchanged |
| Hills Bank & Trust Co |
| 0.13% | 0.18% | #12 | $3.0M | 872,200 | $3.6M | 872,200 | 00.00% | Unchanged |
| NORTHERN TRUST CORP |
| <0.01% | <0.01% | #64 | $2.7M | 791,774 | $2.2M | 528,928 | +262,846+49.69% | Add |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #60 | $2.6M | 773,262 | $2.8M | 661,318 | +111,944+16.93% | Add |
| Ally Bridge Group (NY) LLC |
| 2.24% | 3.12% | #5 | $2.5M | 743,958 | $3.9M | 926,557 | -182,599-19.71% | Reduce |
| VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #57 | $2.0M | 589,003 | $2.4M | 566,676 | +22,327+3.94% | Add |
| BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #82 | $1.6M | 465,454 | $1.0M | 241,924 | +223,530+92.40% | Add |
| UBS Group AG |
| <0.01% | <0.01% | #72 | $1.5M | 444,917 | $2.2M | 520,905 | -75,988-14.59% | Reduce |
| WealthPlan Investment Management, LLC |
| 0.07% | 0.09% | #15 | $1.4M | 404,071 | $1.7M | 404,071 | 00.00% | Unchanged |
| VOYA INVESTMENT MANAGEMENT LLC |
| <0.01% | <0.01% | #41 | $1.2M | 337,501 | $481,589 | 115,489 | +222,012+192.24% | Add |
| Nuveen, LLC |
| <0.01% | <0.01% | #67 | $1.1M | 336,817 | $3.8M | 910,221 | -573,404-63.00% | Reduce |
| CITIGROUP INC |
| <0.01% | <0.01% | #59 | $1.1M | 334,917 | $884,586 | 212,131 | +122,786+57.88% | Add |
| Seven Fleet Capital Management LP |
| 0.19% | 0.5% | #11 | $1.1M | 332,613 | $1.6M | 379,082 | -46,469-12.26% | Reduce |
| FMR LLC |
| <0.01% | <0.01% | #96 | $1.1M | 327,253 | $1.3M | 313,658 | +13,595+4.33% | Add |
| Bank of New York Mellon Corp |
| <0.01% | <0.01% | #76 | $1.0M | 297,722 | $772,845 | 185,335 | +112,387+60.64% | Add |
| GSA CAPITAL PARTNERS LLP |
| 0.06% | 0.01% | #16 | $1.0M | 293,782 | $156,000 | 37,317 | +256,465+687.26% | Add |
| FEDERATED HERMES, INC. |
| <0.01% | <0.01% | #40 | $740,048 | 217,023 | $926,332 | 222,142 | -5,119-2.30% | Reduce |
| STATE OF WISCONSIN INVESTMENT BOARD |
| <0.01% | <0.01% | #38 | $620,149 | 181,862 | $496,705 | 119,114 | +62,748+52.68% | Add |
| ALLIANCEBERNSTEIN L.P. |
| <0.01% | <0.01% | #74 | $500,525 | 120,030 | $229,543 | 83,470 | +36,560+43.80% | Add |
| RHUMBLINE ADVISERS |
| <0.01% | <0.01% | #63 | $420,441 | 123,299 | $321,456 | 77,090 | +46,209+59.94% | Add |
| AMERICAN CENTURY COMPANIES INC |
| <0.01% | <0.01% | #73 | $412,774 | 121,048 | $148,961 | 35,722 | +85,326+238.86% | Add |
| BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #71 | $412,231 | 120,889 | $90,326 | 21,661 | +99,228+458.10% | Add |
| Rafferty Asset Management, LLC |
| <0.01% | <0.01% | #45 | $382,582 | 112,194 | $387,026 | 92,812 | +19,382+20.88% | Add |
| Walleye Capital LLC |
| <0.01% | — | #36 | $377,337 | 110,656 | $0 | 0 | +110,656 | New Buy |
| DEUTSCHE BANK AG\ |
| <0.01% | <0.01% | #83 | $343,581 | 100,757 | $221,690 | 53,163 | +47,594+89.52% | Add |
| Trueblood Wealth Management, LLC |
| 0.12% | 0.16% | #13 | $340,113 | 99,740 | $413,084 | 99,061 | +679+0.69% | Add |
| WELLS FARGO & COMPANY/MN |
| <0.01% | <0.01% | #97 | $294,931 | 86,490 | $97,957 | 23,491 | +62,999+268.18% | Add |
| PRICE T ROWE ASSOCIATES INC /MD/ |
| <0.01% | <0.01% | #105 | $293,021 | 85,930 | $177,000 | 42,282 | +43,648+103.23% | Add |
| GROUP ONE TRADING LLC |
| <0.01% | <0.01% | #58 | $281,325 | 82,500 | $8,986 | 2,155 | +80,345+3,728.31% | Add |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #107 | $260,486 | 76,389 | $1.1M | 252,930 | -176,541-69.80% | Reduce |
