| BlackRock, Inc. |
| <0.01% | <0.01% | #61 | $13.8M | 7.8M | $4.1M | 2.1M | +5.7M+264.70% | Add |
| PFIZER INC |
| 4.63% | 3.5% | #1 | $7.9M | 4.7M | $8.3M | 4.7M | 00.00% | Unchanged |
| VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #65 | $7.4M | 4.2M | $7.2M | 3.8M | +441,340+11.72% | Add |
| MACKENZIE FINANCIAL CORP |
| 0.01% | <0.01% | #18 | $6.4M | 3.7M | $1.8M | 942,786 | +2.7M+287.23% | Add |
| RENAISSANCE TECHNOLOGIES LLC |
| 0.01% | 0.01% | #17 | $4.9M | 2.8M | $4.9M | 2.6M | +183,048+7.07% | Add |
| Kynam Capital Management, LP |
| 0.24% | 0.29% | #4 | $4.4M | 2.5M | $4.8M | 2.5M | 00.00% | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #59 | $4.2M | 2.4M | $1.9M | 1.0M | +1.4M+133.30% | Add |
| ACADIAN ASSET MANAGEMENT LLC |
| <0.01% | <0.01% | #24 | $3.1M | 1.8M | $1.8M | 925,039 | +849,435+91.83% | Add |
| STATE STREET CORP |
| <0.01% | <0.01% | #74 | $2.9M | 1.6M | $804,200 | 423,263 | +1.2M+285.79% | Add |
| BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #64 | $2.5M | 1.4M | $2.5M | 1.3M | +113,791+8.77% | Add |
| TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #37 | $1.8M | 1.0M | $3.3M | 1.8M | -713,655-40.55% | Reduce |
| DIMENSIONAL FUND ADVISORS LP |
| <0.01% | <0.01% | #53 | $1.7M | 975,327 | $1.3M | 673,200 | +302,127+44.88% | Add |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #63 | $1.4M | 775,809 | $1.1M | 559,642 | +216,167+38.63% | Add |
| FMR LLC |
| <0.01% | <0.01% | #88 | $1.3M | 727,115 | $1.4M | 723,959 | +3,156+0.44% | Add |
| NORTHERN TRUST CORP |
| <0.01% | <0.01% | #66 | $1.3M | 712,965 | $413,696 | 217,735 | +495,230+227.45% | Add |
| MAVERICK CAPITAL LTD |
| 0.01% | 0.01% | #13 | $1.1M | 652,542 | $1.2M | 652,542 | 00.00% | Unchanged |
| VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | — | #93 | $1.1M | 613,801 | $0 | 0 | +613,801 | New Buy |
| VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #57 | $1.1M | 606,388 | $988,224 | 520,118 | +86,270+16.59% | Add |
| Qube Research & Technologies Ltd |
| <0.01% | <0.01% | #38 | $960,529 | 545,755 | $335,724 | 176,697 | +369,058+208.86% | Add |
| UBS Group AG |
| <0.01% | <0.01% | #68 | $910,573 | 517,371 | $492,421 | 259,169 | +258,202+99.63% | Add |
| 72 Investment Holdings, LLC |
| 1.67% | 1.82% | #2 | $834,358 | 474,067 | $900,727 | 474,067 | 00.00% | Unchanged |
| GSA CAPITAL PARTNERS LLP |
| 0.05% | 0.06% | #10 | $815,612 | 463,416 | $913,000 | 480,724 | -17,308-3.60% | Reduce |
| JACOBS LEVY EQUITY MANAGEMENT, INC |
| <0.01% | <0.01% | #28 | $723,323 | 410,979 | $681,988 | 358,941 | +52,038+14.50% | Add |
| Cambridge Investment Research Advisors, Inc. |
| <0.01% | <0.01% | #33 | $673,042 | 382,410 | $1.0M | 547,014 | -164,604-30.09% | Reduce |
| MARSHALL WACE, LLP |
| <0.01% | <0.01% | #41 | $661,205 | 375,686 | $2.3M | 1.2M | -829,982-68.84% | Reduce |
| Green Alpha Advisors, LLC |
| 0.43% | 0.7% | #3 | $641,210 | 364,324 | $709,935 | 373,650 | -9,326-2.50% | Reduce |
| PFM Health Sciences, LP |
| 0.05% | 0.17% | #9 | $624,249 | 354,687 | $1.8M | 957,787 | -603,100-62.97% | Reduce |
| GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #92 | $568,260 | 322,875 | $715,519 | 376,589 | -53,714-14.26% | Reduce |
| Invesco Ltd. |
| <0.01% | <0.01% | #97 | $529,966 | 301,117 | $158,654 | 83,502 | +217,615+260.61% | Add |
| WELLS FARGO & COMPANY/MN |
| <0.01% | <0.01% | #75 | $525,035 | 298,315 | $576,945 | 303,655 | -5,340-1.76% | Reduce |
| XTX Topco Ltd |
| 0.01% | 0.01% | #19 | $473,716 | 269,157 | $614,591 | 323,469 | -54,312-16.79% | Reduce |
| Bruce & Co., Inc. |
| 0.12% | 0.14% | #6 | $440,000 | 250,000 | $475,000 | 250,000 | 00.00% | Unchanged |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #105 | $431,753 | 245,314 | $2.0M | 1.0M | -801,889-76.57% | Reduce |
| Man Group plc |
| <0.01% | <0.01% | #39 | $422,516 | 240,066 | $146,699 | 77,210 | +162,856+210.93% | Add |
| Bank of New York Mellon Corp |
| <0.01% | <0.01% | #83 | $391,706 | 222,560 | $23,772 | 12,511 | +210,049+1,678.91% | Add |
| MILESTONE ASSET MANAGEMENT, LLC |
| 0.06% | 0.06% | #8 | $352,150 | 200,085 | $307,944 | 162,076 | +38,009+23.45% | Add |
| CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #99 | $348,154 | 197,815 | $566,073 | 297,933 | -100,118-33.60% | Reduce |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
| <0.01% | <0.01% | #48 | $305,140 | 173,375 | $168,125 | 88,487 | +84,888+95.93% | Add |
| Susquehanna Portfolio Strategies, LLC |
| <0.01% | — | #22 | $279,131 | 158,597 | $0 | 0 | +158,597 | New Buy |
| Graham Capital Management, L.P. |
| <0.01% | <0.01% | #20 | $274,409 | 155,914 | $73,627 | 38,751 | +117,163+302.35% | Add |
| AMERICAN CENTURY COMPANIES INC |
| <0.01% | <0.01% | #69 | $247,421 | 140,580 | $213,661 | 112,453 | +28,127+25.01% | Add |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC |
| <0.01% | 0.01% | #23 | $232,320 | 132,000 | $250,800 | 132,000 | 00.00% | Unchanged |
| Nuveen, LLC |
| <0.01% | — | #90 | $217,388 | 123,516 | $0 | 0 | +123,516 | New Buy |
| LPL Financial LLC |
| <0.01% | <0.01% | #94 | $216,082 | 122,774 | $67,021 | 35,274 | +87,500+248.06% | Add |
| MORGAN STANLEY |
| <0.01% | <0.01% | #122 | $213,523 | 121,320 | $834,650 | 358,219 | -236,899-66.13% | Reduce |
| NANO CAP NEW MILLENNIUM GROWTH FUND L P |
| 0.16% | 0.21% | #5 | $206,800 | 117,500 | $223,250 | 117,500 | 00.00% | Unchanged |
| JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #118 | $200,519 | 113,931 | $211,803 | 111,475 | +2,456+2.20% | Add |
| DEUTSCHE BANK AG\ |
| <0.01% | — | #95 | $157,652 | 89,575 | $0 | 0 | +89,575 | New Buy |
| Quadrature Capital Ltd |
| <0.01% | <0.01% | #36 | $156,603 | 88,979 | $75,156 | 39,556 | +49,423+124.94% | Add |
| CANADA PENSION PLAN INVESTMENT BOARD |
| <0.01% | <0.01% | #77 | $142,736 | 81,100 | $110,010 | 57,900 | +23,200+40.07% | Add |
