BICYCLE THERAPEUTICS PLC SPON ADS EACH REP 1 ORD SHS · 13F Institutional Holdings
| Ownership Trend | Portfolio % | Prev Q % | Rank | Q2 2026 Value | Q2 2026 Shares | Prev Q Value | Prev Q Shares | Shares Change | Action | |
|---|---|---|---|---|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | 0.23% | 0.29% | #10 | $46.2M | 10.9M | $50.5M | 10.9M | 00.00% | Unchanged | |
| FCPM III SERVICES B.V. | 1.96% | 2.23% | #1 | $14.7M | 3.5M | $16.1M | 3.5M | 00.00% | Unchanged | |
| ARMISTICE CAPITAL, LLC | 0.18% | 0.28% | #12 | $14.4M | 3.4M | $15.8M | 3.4M | 00.00% | Unchanged | |
| Long Focus Capital Management, LLC | 0.36% | 0.4% | #7 | $14.0M | 3.3M | $15.4M | 3.3M | 00.00% | Unchanged | |
| ACADIAN ASSET MANAGEMENT LLC | 0.01% | 0.01% | #27 | $8.3M | 2.0M | $9.1M | 2.0M | 00.00% | Unchanged | |
| RENAISSANCE TECHNOLOGIES LLC | 0.01% | 0.01% | #29 | $6.5M | 1.5M | $4.5M | 979,300 | +554,100+56.58% | Add | |
| GSK plc | 1.08% | 1.18% | #3 | $6.5M | 1.5M | $7.1M | 1.5M | 00.00% | Unchanged | |
| PRICE T ROWE ASSOCIATES INC /MD/ | <0.01% | <0.01% | #58 | $3.8M | 902,150 | $4.8M | 1.0M | -126,093-12.26% | Reduce | |
| MARSHALL WACE, LLP | <0.01% | <0.01% | #39 | $3.4M | 797,940 | $1.8M | 377,335 | +420,605+111.47% | Add | |
| Qube Research & Technologies Ltd | <0.01% | <0.01% | #37 | $3.3M | 775,567 | $1.4M | 308,617 | +466,950+151.30% | Add | |
| MORGAN STANLEY | <0.01% | <0.01% | #72 | $2.8M | 667,269 | $6.4M | 822,705 | -155,436-18.89% | Reduce | |
| CITADEL ADVISORS LLC | <0.01% | <0.01% | #61 | $2.7M | 627,725 | $1.9M | 410,685 | +217,040+52.85% | Add | |
| SCHRODER INVESTMENT MANAGEMENT GROUP | <0.01% | <0.01% | #41 | $2.6M | 615,833 | $2.7M | 615,833 | 00.00% | Unchanged | |
| MILLENNIUM MANAGEMENT LLC | <0.01% | <0.01% | #47 | $2.3M | 553,967 | $1.3M | 283,986 | +269,981+95.07% | Add | |
| Peapod Lane Capital LLC | 1.54% | 0.45% | #2 | $2.3M | 537,978 | $550,207 | 121,106 | +416,872+344.22% | Add | |
| DIADEMA PARTNERS LP | 0.24% | 0.38% | #9 | $2.0M | 462,724 | $2.2M | 476,424 | -13,700-2.88% | Reduce | |
| JANE STREET GROUP, LLC | <0.01% | <0.01% | #70 | $1.9M | 454,763 | $1.4M | 303,015 | +151,748+50.08% | Add | |
| TWO SIGMA INVESTMENTS, LP | <0.01% | <0.01% | #44 | $1.8M | 434,577 | $764,672 | 164,800 | +269,777+163.70% | Add | |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | <0.01% | <0.01% | #73 | $1.5M | 352,357 | $1.4M | 296,788 | +55,569+18.72% | Add | |
| Birchview Capital, LP | 0.6% | 1.22% | #6 | $1.3M | 313,616 | $2.2M | 463,599 | -149,983-32.35% | Reduce | |
| BlackRock, Inc. | <0.01% | <0.01% | #84 | $1.2M | 280,386 | $1.3M | 278,992 | +1,394+0.50% | Add | |
| MOORE CAPITAL MANAGEMENT, LP | 0.02% | 0.03% | #24 | $1.2M | 275,000 | $1.3M | 275,000 | 00.00% | Unchanged | |
| Rangeley Capital, LLC | 1.03% | 1.05% | #4 | $1.1M | 253,500 | $1.1M | 232,260 | +21,240+9.14% | Add | |
| FLAX POND CAPITAL, LLC | 0.69% | 0.66% | #5 | $910,071 | 196,136 | $817,271 | 176,136 | +20,000+11.35% | Add | |
| Palo Alto Investors LP | 0.13% | 0.14% | #14 | $856,014 | 201,890 | $936,770 | 201,890 | 00.00% | Unchanged | |
| Sculptor Capital LP | 0.01% | — | #32 | $839,113 | 197,904 | $0 | 0 | +197,904 | New Buy | |
| Eversept Partners, LP | 0.04% | 0.05% | #19 | $808,632 | 190,715 | $884,918 | 190,715 | 00.00% | Unchanged | |
| PINNACLE ASSOCIATES LTD | 0.01% | 0.01% | #30 | $805,558 | 189,990 | $860,302 | 185,410 | +4,580+2.47% | Add | |
| Jump Financial, LLC | 0.01% | <0.01% | #34 | $708,504 | 167,100 | $243,804 | 52,544 | +114,556+218.02% | Add | |
| Point72 Asset Management, L.P. | <0.01% | <0.01% | #50 | $635,729 | 149,936 | $605,158 | 130,422 | +19,514+14.96% | Add | |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | <0.01% | <0.01% | #56 | $542,139 | 127,863 | $593,284 | 127,863 | 00.00% | Unchanged | |
| GOLDMAN SACHS GROUP INC | <0.01% | <0.01% | #82 | $514,231 | 121,281 | $511,082 | 110,147 | +11,134+10.11% | Add | |
| Persistent Asset Partners Ltd | 0.15% | 0.21% | #13 | $497,157 | 117,254 | $558,828 | 120,437 | -3,183-2.64% | Reduce | |
| XTX Topco Ltd | 0.01% | 0.01% | #33 | $465,556 | 109,801 | $493,659 | 106,392 | +3,409+3.20% | Add | |
| Quadrature Capital Ltd | <0.01% | — | #36 | $441,350 | 104,092 | $0 | 0 | +104,092 | New Buy | |
| TD ASSET MANAGEMENT INC | <0.01% | <0.01% | #59 | $390,046 | 91,992 | $426,843 | 91,992 | 00.00% | Unchanged | |
| Virtus Investment Advisers, LLC | 0.08% | 0.05% | #17 | $342,545 | 80,789 | $169,829 | 36,601 | +44,188+120.73% | Add | |
| NANO CAP NEW MILLENNIUM GROWTH FUND L P | 0.26% | — | #8 | $339,200 | 80,000 | $0 | 0 | +80,000 | New Buy | |
| EntryPoint Capital, LLC | 0.08% | 0.09% | #16 | $329,630 | 77,743 | $296,524 | 63,906 | +13,837+21.65% | Add | |
| Marquette Asset Management, LLC | 0.04% | — | #21 | $308,901 | 72,854 | $0 | 0 | +72,854 | New Buy | |
| HRT FINANCIAL LP | <0.01% | <0.01% | #54 | $280,845 | 66,237 | $213,000 | 45,915 | +20,322+44.26% | Add | |
| DAFNA Capital Management LLC | 0.05% | 0.07% | #18 | $273,446 | 64,492 | $299,243 | 64,492 | 00.00% | Unchanged | |
| State of Tennessee, Department of Treasury | <0.01% | <0.01% | #49 | $259,289 | 61,153 | $283,750 | 61,153 | 00.00% | Unchanged | |
| SEI INVESTMENTS CO | <0.01% | <0.01% | #67 | $223,804 | 52,784 | $244,918 | 52,784 | 00.00% | Unchanged | |
| ALPS ADVISORS INC | <0.01% | <0.01% | #46 | $216,757 | 51,122 | $188,621 | 40,651 | +10,471+25.76% | Add | |
| Verdad Advisers, LP | 0.21% | — | #11 | $216,664 | 51,100 | $0 | 0 | +51,100 | New Buy | |
| ADAR1 Capital Management, LLC | 0.01% | 0.02% | #28 | $214,705 | 50,638 | $330,823 | 71,298 | -20,660-28.98% | Reduce | |
| SIMPLEX TRADING, LLC | <0.01% | <0.01% | #74 | $149,383 | 35,232 | $853,759 | 184,000 | -148,768-80.85% | Reduce | |
| WOODSTOCK CORP | 0.01% | 0.01% | #26 | $135,237 | 29,146 | $135,237 | 29,146 | 00.00% | Unchanged | |
| Trexquant Investment LP | <0.01% | — | #48 | $131,627 | 31,044 | $0 | 0 | +31,044 | New Buy |