| BlackRock, Inc. |
| <0.01% | <0.01% | #92 | $119.9M | 23.5M | $126.8M | 21.2M | +2.3M+11.06% | Add |
| Rubric Capital Management LP |
| 0.76% | 0.12% | #6 | $82.6M | 16.2M | $11.1M | 1.9M | +14.3M+770.69% | Add |
| MILLENNIUM MANAGEMENT LLC |
| 0.02% | 0.04% | #39 | $72.8M | 14.3M | $108.1M | 18.0M | -3.8M-20.90% | Reduce |
| STATE STREET CORP |
| <0.01% | <0.01% | #88 | $68.1M | 13.4M | $81.5M | 13.6M | -248,179-1.82% | Reduce |
| VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #111 | $53.4M | 10.5M | $62.1M | 10.4M | +105,982+1.02% | Add |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. |
| 0.07% | 0.08% | #29 | $48.7M | 9.5M | $48.9M | 8.2M | +1.4M+16.86% | Add |
| VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #91 | $40.9M | 8.0M | $39.9M | 6.7M | +1.4M+20.49% | Add |
| GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #93 | $32.7M | 6.4M | $36.0M | 6.0M | +394,281+6.56% | Add |
| Jupiter Topco LLC |
| 0.01% | — | #53 | $27.0M | 5.3M | $0 | 0 | +5.3M | New Buy |
| TWO SIGMA INVESTMENTS, LP |
| 0.02% | 0.02% | #44 | $26.6M | 5.2M | $25.6M | 4.3M | +935,780+21.89% | Add |
| Nuveen, LLC |
| <0.01% | 0.01% | #65 | $20.4M | 4.0M | $31.4M | 5.2M | -1.2M-23.64% | Reduce |
| GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #97 | $18.8M | 3.7M | $19.3M | 3.2M | +468,824+14.58% | Add |
| AIGH Capital Management LLC |
| 1.03% | — | #3 | $16.3M | 3.2M | $0 | 0 | +3.2M | New Buy |
| MORGAN STANLEY |
| <0.01% | <0.01% | #135 | $12.2M | 2.4M | $15.9M | 2.9M | -495,794-17.18% | Reduce |
| AQR CAPITAL MANAGEMENT LLC |
| <0.01% | 0.01% | #69 | $11.8M | 2.3M | $14.6M | 2.4M | -123,230-5.05% | Reduce |
| NORTHERN TRUST CORP |
| <0.01% | <0.01% | #104 | $11.6M | 2.3M | $12.4M | 2.1M | +209,096+10.10% | Add |
| Rock Springs Capital Management LP |
| 0.56% | 0.81% | #8 | $11.4M | 2.2M | $13.8M | 2.3M | -57,704-2.51% | Reduce |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #100 | $11.3M | 2.2M | $12.7M | 2.1M | +97,662+4.62% | Add |
| BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #131 | $11.0M | 2.2M | $14.0M | 2.3M | -173,494-7.42% | Reduce |
| Qube Research & Technologies Ltd |
| 0.01% | 0.02% | #54 | $10.7M | 2.1M | $14.6M | 2.4M | -344,873-14.16% | Reduce |
| JONES FINANCIAL COMPANIES LLLP |
| <0.01% | <0.01% | #71 | $9.8M | 1.8M | $10.2M | 1.9M | -92,959-5.00% | Reduce |
| VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #90 | $8.9M | 1.8M | $10.1M | 1.7M | +76,708+4.57% | Add |
| Eversept Partners, LP |
| 0.44% | 0.7% | #10 | $8.6M | 1.7M | $13.4M | 2.2M | -551,101-24.72% | Reduce |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #136 | $8.3M | 1.6M | $7.7M | 1.3M | +338,669+26.42% | Add |
| J. Goldman & Co LP |
| 0.21% | 0.52% | #15 | $8.1M | 1.6M | $18.0M | 3.0M | -1.4M-47.35% | Reduce |
| CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #122 | $7.2M | 1.4M | $22.5M | 3.8M | -2.3M-62.27% | Reduce |
| Invesco Ltd. |
| <0.01% | <0.01% | #142 | $7.0M | 1.4M | $1.9M | 312,712 | +1.1M+337.74% | Add |
| FIRST TRUST ADVISORS LP |
| <0.01% | 0.01% | #72 | $6.6M | 1.3M | $9.0M | 1.5M | -197,174-13.16% | Reduce |
| Hennion & Walsh Asset Management, Inc. |
| 0.18% | 0.2% | #18 | $6.2M | 1.2M | $6.0M | 1.0M | +210,209+20.99% | Add |
| SCHRODER INVESTMENT MANAGEMENT GROUP |
| <0.01% | <0.01% | #68 | $6.1M | 1.2M | $2.3M | 419,768 | +741,470+176.64% | Add |
| RENAISSANCE TECHNOLOGIES LLC |
| 0.01% | 0.01% | #63 | $4.6M | 892,593 | $7.6M | 1.3M | -379,848-29.85% | Reduce |
| PANAGORA ASSET MANAGEMENT INC |
| 0.01% | — | #47 | $4.5M | 890,944 | $0 | 0 | +890,944 | New Buy |
| BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #89 | $4.1M | 810,322 | $4.2M | 698,744 | +111,578+15.97% | Add |
| DEUTSCHE BANK AG\ |
| <0.01% | <0.01% | #110 | $3.9M | 770,910 | $4.2M | 708,589 | +62,321+8.80% | Add |
| ExodusPoint Capital Management, LP |
| 0.02% | — | #38 | $3.8M | 752,923 | $0 | 0 | +752,923 | New Buy |
| Bank of New York Mellon Corp |
| <0.01% | <0.01% | #138 | $3.8M | 749,676 | $4.2M | 700,783 | +48,893+6.98% | Add |
| Squarepoint Ops LLC |
| <0.01% | <0.01% | #70 | $3.6M | 715,262 | $4.2M | 697,284 | +17,978+2.58% | Add |
| SECTOR GAMMA AS |
| 0.76% | 0.73% | #5 | $3.5M | 686,844 | $3.1M | 516,131 | +170,713+33.08% | Add |
| Trexquant Investment LP |
| 0.02% | 0.03% | #42 | $3.4M | 660,586 | $4.8M | 804,734 | -144,148-17.91% | Reduce |
| Redmile Group, LLC |
| 0.22% | 0.29% | #14 | $3.3M | 641,750 | $4.4M | 733,350 | -91,600-12.49% | Reduce |
| RAYMOND JAMES FINANCIAL INC |
| <0.01% | <0.01% | #119 | $3.1M | 612,672 | $3.2M | 536,712 | +75,960+14.15% | Add |
| UBS Group AG |
| <0.01% | <0.01% | #161 | $2.8M | 551,721 | $4.1M | 688,649 | -136,928-19.88% | Reduce |
| Jump Financial, LLC |
| 0.02% | — | #41 | $2.7M | 536,981 | $0 | 0 | +536,981 | New Buy |
| Krensavage Asset Management, LLC |
| 1.04% | 1.17% | #2 | $2.7M | 534,523 | $3.0M | 500,000 | +34,523+6.90% | Add |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
| <0.01% | <0.01% | #151 | $2.5M | 486,412 | $2.6M | 440,674 | +45,738+10.38% | Add |
| Caption Management, LLC |
| 0.01% | 0.02% | #52 | $2.4M | 480,000 | $2.7M | 454,200 | +25,800+5.68% | Add |
| MACKENZIE FINANCIAL CORP |
| <0.01% | — | #86 | $2.4M | 474,094 | $0 | 0 | +474,094 | New Buy |
| Swiss National Bank |
| <0.01% | <0.01% | #107 | $2.4M | 467,600 | $2.9M | 480,800 | -13,200-2.75% | Reduce |
| HUSSMAN STRATEGIC ADVISORS, INC. |
| 0.49% | — | #9 | $2.1M | 420,000 | $0 | 0 | +420,000 | New Buy |
| Universal- Beteiligungs- und Servicegesellschaft mbH |
| <0.01% | <0.01% | #78 | $2.1M | 411,386 | $2.1M | 357,180 | +54,206+15.18% | Add |