| BlackRock, Inc. |
| <0.01% | <0.01% | #82 | $136.9M | 32.1M | $70.1M | 28.6M | +3.5M+12.35% | Add |
| Rubric Capital Management LP |
| 0.7% | 0.09% | #4 | $76.7M | 18.0M | $8.9M | 3.6M | +14.4M+397.18% | Add |
| STATE STREET CORP |
| <0.01% | <0.01% | #81 | $68.9M | 16.2M | $45.8M | 18.7M | -2.5M-13.43% | Reduce |
| VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #112 | $56.1M | 13.2M | $31.6M | 12.9M | +278,326+2.16% | Add |
| GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #88 | $33.9M | 7.9M | $18.4M | 7.5M | +442,056+5.89% | Add |
| WELLINGTON MANAGEMENT GROUP LLP |
| 0.01% | <0.01% | #47 | $33.4M | 7.8M | $8.0M | 3.3M | +4.6M+138.94% | Add |
| Frazier Life Sciences Management, L.P. |
| 0.61% | 0.37% | #5 | $28.1M | 6.6M | $14.5M | 5.9M | +700,000+11.86% | Add |
| Deep Track Capital, LP |
| 0.37% | — | #9 | $25.6M | 6.0M | $0 | 0 | +6.0M | New Buy |
| 180 WEALTH ADVISORS, LLC |
| 2.12% | 1.2% | #3 | $21.1M | 5.0M | $10.5M | 4.3M | +668,148+15.57% | Add |
| FMR LLC |
| <0.01% | <0.01% | #138 | $17.5M | 4.1M | $8.5M | 3.5M | +620,082+17.81% | Add |
| TSP Capital Management Group, LLC |
| 4.05% | 2% | #1 | $16.9M | 4.0M | $8.2M | 3.3M | +628,700+18.80% | Add |
| AQR CAPITAL MANAGEMENT LLC |
| 0.01% | <0.01% | #48 | $16.2M | 3.8M | $1.1M | 452,986 | +3.4M+740.83% | Add |
| MORGAN STANLEY |
| <0.01% | <0.01% | #135 | $14.8M | 3.5M | $20.7M | 3.9M | -375,581-9.75% | Reduce |
| BRAIDWELL LP |
| 0.54% | — | #7 | $14.7M | 3.5M | $0 | 0 | +3.5M | New Buy |
| VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #156 | $12.8M | 3.0M | $7.8M | 3.2M | -169,655-5.35% | Reduce |
| NORTHERN TRUST CORP |
| <0.01% | <0.01% | #105 | $12.3M | 2.9M | $6.6M | 2.7M | +211,340+7.90% | Add |
| UBS Group AG |
| <0.01% | <0.01% | #99 | $12.3M | 2.9M | $20.2M | 8.3M | -5.4M-65.04% | Reduce |
| TWO SIGMA INVESTMENTS, LP |
| 0.01% | 0.01% | #38 | $11.5M | 2.7M | $7.1M | 2.9M | -202,162-6.98% | Reduce |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #102 | $11.1M | 2.6M | $6.2M | 2.5M | +49,660+1.95% | Add |
| BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #146 | $10.1M | 2.4M | $8.3M | 3.4M | -1.0M-30.11% | Reduce |
| VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #80 | $9.4M | 2.2M | $5.2M | 2.1M | +59,142+2.77% | Add |
| GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #131 | $9.2M | 2.2M | $7.2M | 2.9M | -787,821-26.78% | Reduce |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #154 | $7.7M | 1.8M | $4.3M | 1.7M | +57,241+3.28% | Add |
| WELLS FARGO & COMPANY/MN |
| <0.01% | <0.01% | #118 | $6.3M | 1.5M | $2.1M | 860,474 | +615,939+71.58% | Add |
| Caption Management, LLC |
| 0.03% | 0.02% | #21 | $5.7M | 1.3M | $3.5M | 1.4M | -78,021-5.53% | Reduce |
| CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #147 | $5.6M | 1.3M | $4.0M | 1.6M | -300,771-18.50% | Reduce |
| DIMENSIONAL FUND ADVISORS LP |
| <0.01% | <0.01% | #127 | $4.7M | 1.1M | $12.1M | 5.0M | -3.9M-77.91% | Reduce |
| Bank of New York Mellon Corp |
| <0.01% | <0.01% | #149 | $3.8M | 898,463 | $2.1M | 845,526 | +52,937+6.26% | Add |
| J. Goldman & Co LP |
| 0.09% | — | #14 | $3.5M | 816,589 | $0 | 0 | +816,589 | New Buy |
| SCOPIA CAPITAL MANAGEMENT LP |
| 2.65% | 1.17% | #2 | $3.0M | 694,961 | $1.7M | 694,961 | 00.00% | Unchanged |
| BALYASNY ASSET MANAGEMENT L.P. |
| <0.01% | <0.01% | #57 | $2.9M | 684,107 | $505,957 | 206,513 | +477,594+231.27% | Add |
| VICTORY CAPITAL MANAGEMENT INC |
| <0.01% | <0.01% | #100 | $2.8M | 650,565 | $3.0M | 1.2M | -581,513-47.20% | Reduce |
| Nuveen, LLC |
| <0.01% | <0.01% | #145 | $2.7M | 635,732 | $5.3M | 2.2M | -1.5M-70.63% | Reduce |
| DELTEC ASSET MANAGEMENT LLC |
| 0.4% | 0.19% | #8 | $2.7M | 628,000 | $1.0M | 428,000 | +200,000+46.73% | Add |
| Jupiter Topco LLC |
| <0.01% | — | #117 | $2.5M | 591,665 | $0 | 0 | +591,665 | New Buy |
| Swiss National Bank |
| <0.01% | <0.01% | #109 | $2.5M | 587,400 | $1.4M | 574,700 | +12,700+2.21% | Add |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
| <0.01% | <0.01% | #173 | $2.3M | 537,134 | $3.0M | 1.2M | -695,508-56.42% | Reduce |
| STATE OF WISCONSIN INVESTMENT BOARD |
| <0.01% | <0.01% | #53 | $2.2M | 511,045 | $390,197 | 159,264 | +351,781+220.88% | Add |
| JACOBS LEVY EQUITY MANAGEMENT, INC |
| 0.01% | <0.01% | #40 | $2.1M | 494,493 | $106,433 | 43,442 | +451,051+1,038.28% | Add |
| 1492 Capital Management LLC |
| 0.61% | 0.51% | #6 | $2.1M | 481,722 | $1.3M | 549,782 | -68,060-12.38% | Reduce |
| Mariner, LLC |
| <0.01% | <0.01% | #79 | $2.0M | 474,236 | $518,117 | 211,476 | +262,760+124.25% | Add |
| PRICE T ROWE ASSOCIATES INC /MD/ |
| <0.01% | <0.01% | #196 | $2.0M | 471,585 | $931,000 | 379,645 | +91,940+24.22% | Add |
| MILLENNIUM MANAGEMENT LLC |
| <0.01% | 0.01% | #150 | $1.8M | 431,126 | $15.7M | 6.4M | -6.0M-93.25% | Reduce |
| JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #210 | $1.8M | 424,000 | $403,515 | 164,700 | +259,300+157.44% | Add |
| Schonfeld Strategic Advisors LLC |
| 0.01% | <0.01% | #45 | $1.8M | 416,483 | $97,046 | 39,611 | +376,872+951.43% | Add |
| Squarepoint Ops LLC |
| <0.01% | — | #83 | $1.8M | 413,062 | $0 | 0 | +413,062 | New Buy |
| Jefferies Financial Group Inc. |
| 0.01% | 0.01% | #32 | $1.7M | 397,700 | $1.7M | 691,700 | -294,000-42.50% | Reduce |
| ExodusPoint Capital Management, LP |
| 0.01% | — | #33 | $1.7M | 391,141 | $0 | 0 | +391,141 | New Buy |
| PRINCIPAL FINANCIAL GROUP INC |
| <0.01% | <0.01% | #130 | $1.6M | 382,526 | $863,032 | 352,258 | +30,268+8.59% | Add |
| Man Group plc |
| <0.01% | <0.01% | #70 | $1.6M | 381,226 | $1.2M | 474,620 | -93,394-19.68% | Reduce |
