| BlackRock, Inc. |
| <0.01% | <0.01% | #107 | $115.0M | 14.5M | $75.1M | 12.9M | +1.6M+12.20% | Add |
| D. E. Shaw & Co., Inc. |
| 0.03% | 0.03% | #39 | $61.8M | 7.8M | $45.2M | 7.8M | +15,947+0.20% | Add |
| VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | — | #122 | $58.1M | 7.3M | $0 | 0 | +7.3M | New Buy |
| STATE STREET CORP |
| <0.01% | <0.01% | #125 | $38.2M | 4.8M | $27.0M | 4.7M | +163,392+3.51% | Add |
| GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #101 | $37.4M | 4.7M | $24.9M | 4.3M | +427,554+9.96% | Add |
| Nuveen, LLC |
| 0.01% | <0.01% | #57 | $34.7M | 4.4M | $16.9M | 2.9M | +1.5M+50.35% | Add |
| Rosalind Advisors, Inc. |
| 5.46% | 7.53% | #2 | $23.0M | 2.9M | $18.7M | 3.2M | -322,719-9.99% | Reduce |
| Qube Research & Technologies Ltd |
| 0.02% | 0.03% | #43 | $22.9M | 2.9M | $23.9M | 4.1M | -1.2M-29.67% | Reduce |
| VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | — | #135 | $20.8M | 2.6M | $0 | 0 | +2.6M | New Buy |
| WELLINGTON MANAGEMENT GROUP LLP |
| <0.01% | <0.01% | #82 | $18.7M | 2.4M | $12.6M | 2.2M | +193,749+8.92% | Add |
| MORGAN STANLEY |
| <0.01% | <0.01% | #130 | $18.5M | 2.3M | $26.2M | 3.2M | -882,605-27.41% | Reduce |
| Legal & General Group Plc |
| <0.01% | <0.01% | #80 | $15.9M | 2.0M | $11.1M | 1.9M | +104,503+5.48% | Add |
| ARMISTICE CAPITAL, LLC |
| 0.19% | 0.2% | #12 | $15.5M | 2.0M | $11.1M | 1.9M | +48,864+2.56% | Add |
| TWO SIGMA INVESTMENTS, LP |
| 0.01% | 0.01% | #51 | $14.9M | 1.9M | $11.2M | 1.9M | -38,699-2.01% | Reduce |
| Parkman Healthcare Partners LLC |
| 1.47% | 1.03% | #4 | $14.3M | 1.8M | $10.0M | 1.7M | +86,357+5.02% | Add |
| ALGERT GLOBAL LLC |
| 0.16% | 0.1% | #14 | $13.8M | 1.7M | $6.7M | 1.2M | +585,984+50.65% | Add |
| NORTHERN TRUST CORP |
| <0.01% | <0.01% | #113 | $12.7M | 1.6M | $8.4M | 1.4M | +153,132+10.60% | Add |
| GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #127 | $12.6M | 1.6M | $9.4M | 1.6M | -19,578-1.21% | Reduce |
| AQR CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #72 | $12.2M | 1.5M | $8.1M | 1.4M | +146,609+10.51% | Add |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #110 | $11.8M | 1.5M | $7.9M | 1.4M | +132,710+9.76% | Add |
| FEDERATED HERMES, INC. |
| 0.02% | 0.01% | #46 | $11.4M | 1.4M | $5.0M | 856,813 | +577,620+67.41% | Add |
| BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #149 | $11.1M | 1.4M | $5.1M | 874,397 | +522,653+59.77% | Add |
| UBS Group AG |
| <0.01% | <0.01% | #118 | $10.3M | 1.3M | $9.5M | 1.6M | -345,465-20.98% | Reduce |
| Ishara Investments LP |
| 7.04% | 5.63% | #1 | $9.7M | 1.2M | $5.9M | 1.0M | +205,000+20.00% | Add |
| VANGUARD FIDUCIARY TRUST CO |
| <0.01% | — | #98 | $9.7M | 1.2M | $0 | 0 | +1.2M | New Buy |
| KENNEDY CAPITAL MANAGEMENT LLC |
| 0.17% | 0.15% | #13 | $9.6M | 1.2M | $7.2M | 1.2M | -31,624-2.55% | Reduce |
| DIMENSIONAL FUND ADVISORS LP |
| <0.01% | — | #111 | $8.5M | 1.1M | $0 | 0 | +1.1M | New Buy |
| Knott David M Jr |
| 4.48% | 3.72% | #3 | $8.4M | 1.1M | $6.1M | 1.1M | 00.00% | Unchanged |
| JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #165 | $8.2M | 1.1M | $3.4M | 612,479 | +445,588+72.75% | Add |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP |
| <0.01% | <0.01% | #78 | $7.7M | 972,880 | $775,808 | 133,760 | +839,120+627.33% | Add |
| Caption Management, LLC |
| 0.03% | 0.04% | #33 | $7.3M | 921,363 | $6.1M | 1.1M | -130,537-12.41% | Reduce |
| Granahan Investment Management, LLC |
| 0.25% | 0.26% | #10 | $7.1M | 898,753 | $5.3M | 921,854 | -23,101-2.51% | Reduce |
| NORGES BANK |
| <0.01% | <0.01% | #157 | $6.3M | 797,200 | $4.5M | 823,800 | -26,600-3.23% | Reduce |
| CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #152 | $6.1M | 772,564 | $4.3M | 747,234 | +25,330+3.39% | Add |
| ESSEX INVESTMENT MANAGEMENT CO LLC |
| 0.74% | 0.69% | #5 | $5.7M | 715,608 | $4.3M | 747,769 | -32,161-4.30% | Reduce |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
| <0.01% | <0.01% | #129 | $5.4M | 687,632 | $3.9M | 668,074 | +19,558+2.93% | Add |
| VOYA INVESTMENT MANAGEMENT LLC |
| <0.01% | <0.01% | #69 | $5.4M | 685,570 | $3.6M | 625,310 | +60,260+9.64% | Add |
| FMR LLC |
| <0.01% | <0.01% | #200 | $5.1M | 644,057 | $3.0M | 513,076 | +130,981+25.53% | Add |
| Walleye Capital LLC |
| 0.02% | — | #45 | $4.8M | 611,296 | $0 | 0 | +611,296 | New Buy |
| DEUTSCHE BANK AG\ |
| <0.01% | <0.01% | #123 | $4.2M | 529,443 | $3.6M | 623,012 | -93,569-15.02% | Reduce |
| Bank of New York Mellon Corp |
| <0.01% | <0.01% | #155 | $3.9M | 488,441 | $2.5M | 426,285 | +62,156+14.58% | Add |
| FIRST TRUST ADVISORS LP |
| <0.01% | — | #97 | $3.8M | 484,978 | $0 | 0 | +484,978 | New Buy |
| IHT Wealth Management, LLC |
| 0.08% | 0.05% | #25 | $3.8M | 481,871 | $2.2M | 376,476 | +105,395+28.00% | Add |
| PERCEPTIVE ADVISORS LLC |
| 0.06% | — | #28 | $3.7M | 467,013 | $0 | 0 | +467,013 | New Buy |
| ROYCE & ASSOCIATES LP |
| 0.03% | 0.01% | #38 | $3.7M | 461,153 | $1.5M | 256,087 | +205,066+80.08% | Add |
| Man Group plc |
| 0.01% | <0.01% | #62 | $3.6M | 455,380 | $1.6M | 276,422 | +178,958+64.74% | Add |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #190 | $3.6M | 454,518 | $2.6M | 443,171 | +11,347+2.56% | Add |
| Russell Investments Group, Ltd. |
| <0.01% | <0.01% | #90 | $3.5M | 440,731 | $2.2M | 384,195 | +56,536+14.72% | Add |
| BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #108 | $3.4M | 430,488 | $1.5M | 262,787 | +167,701+63.82% | Add |
| STATE OF WISCONSIN INVESTMENT BOARD |
| 0.01% | <0.01% | #61 | $3.4M | 427,513 | $1.8M | 308,546 | +118,967+38.56% | Add |
