| Caligan Partners LP |
| 0.06% | — | #6 | $1.3M | 469,998 | $0 | 0 | +469,998 | New Buy |
| STEMPOINT CAPITAL LP |
| 0.14% | — | #3 | $986,728 | 354,938 | $0 | 0 | +354,938 | New Buy |
| VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #17 | $910,080 | 327,367 | $207,985 | 81,884 | +245,483+299.79% | Add |
| SILVERARC CAPITAL MANAGEMENT, LLC |
| 0.09% | — | #4 | $894,404 | 321,728 | $0 | 0 | +321,728 | New Buy |
| Bleichroeder LP |
| 0.14% | 0.04% | #2 | $802,528 | 288,679 | $254,000 | 100,000 | +188,679+188.68% | Add |
| Jupiter Topco LLC |
| <0.01% | — | #13 | $759,412 | 274,156 | $0 | 0 | +274,156 | New Buy |
| BALYASNY ASSET MANAGEMENT L.P. |
| <0.01% | — | #12 | $611,600 | 220,000 | $0 | 0 | +220,000 | New Buy |
| Nantahala Capital Management, LLC |
| 0.02% | — | #9 | $611,594 | 219,998 | $0 | 0 | +219,998 | New Buy |
| Empery Asset Management, LP |
| 0.61% | — | #1 | $527,102 | 189,605 | $0 | 0 | +189,605 | New Buy |
| DIADEMA PARTNERS LP |
| 0.05% | — | #7 | $384,588 | 138,341 | $0 | 0 | +138,341 | New Buy |
| Stonepine Capital Management, LLC |
| 0.04% | — | #8 | $290,649 | 104,550 | $0 | 0 | +104,550 | New Buy |
| Persistent Asset Partners Ltd |
| 0.08% | — | #5 | $258,493 | 92,983 | $0 | 0 | +92,983 | New Buy |
| BOOTHBAY FUND MANAGEMENT, LLC |
| <0.01% | — | #11 | $236,492 | 85,069 | $0 | 0 | +85,069 | New Buy |
| GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #18 | $148,323 | 53,351 | $134,062 | 52,778 | +573+1.09% | Add |
| VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #16 | $128,492 | 46,220 | $42,095 | 16,573 | +29,647+178.89% | Add |
| Sequoia Financial Advisors, LLC |
| <0.01% | <0.01% | #14 | $60,743 | 21,850 | $47,879 | 18,850 | +3,000+15.92% | Add |
| ACADIAN ASSET MANAGEMENT LLC |
| <0.01% | — | #15 | $46,084 | 16,577 | $0 | 0 | +16,577 | New Buy |
| NORTHERN TRUST CORP |
| <0.01% | — | #19 | $41,252 | 14,839 | $0 | 0 | +14,839 | New Buy |
| Riverview Capital Advisers, LLC |
| 0.01% | 0.02% | #10 | $31,152 | 10,384 | $50,051 | 10,384 | 00.00% | Unchanged |
| BlackRock, Inc. |
| <0.01% | <0.01% | #24 | $13,163 | 4,735 | $12,052 | 4,745 | -10-0.21% | Reduce |
| UBS Group AG |
| <0.01% | <0.01% | #20 | $8,599 | 3,093 | $24,504 | 9,647 | -6,554-67.94% | Reduce |
| BARCLAYS PLC |
| <0.01% | — | #23 | $1,560 | 561 | $0 | 0 | +561 | New Buy |
| MORGAN STANLEY |
| <0.01% | <0.01% | #25 | $1,418 | 510 | $2,856 | 510 | 00.00% | Unchanged |
| TD Waterhouse Canada Inc. |
| <0.01% | <0.01% | #22 | $178 | 63 | $154 | 63 | 00.00% | Unchanged |
| SBI Securities Co., Ltd. |
| <0.01% | <0.01% | #21 | $31 | 11 | $28 | 11 | 00.00% | Unchanged |
| OSAIC HOLDINGS, INC. |
| <0.01% | <0.01% | #26 | $18 | 7 | $2 | 1 | +6+600.00% | Add |
| JONES FINANCIAL COMPANIES LLLP |
| <0.01% | <0.01% | #29 | $8 | 3 | $8 | 3 | 00.00% | Unchanged |
| US BANCORP \DE\ |
| <0.01% | <0.01% | #28 | $8 | 3 | $8 | 3 | 00.00% | Unchanged |
| DANSKE BANK A/S |
| <0.01% | <0.01% | #27 | $6 | 2 | $5 | 2 | 00.00% | Unchanged |
