| Ikarian Capital, LLC |
| 0.35% | 0.15% | #1 | $3.3M | 503,153 | $1.8M | 553,153 | -50,000-9.04% | Reduce |
| RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #4 | $3.1M | 478,263 | $1.5M | 470,696 | +7,567+1.61% | Add |
| VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #20 | $2.5M | 379,478 | $1.2M | 361,759 | +17,719+4.90% | Add |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #13 | $1.8M | 280,400 | $238,875 | 73,500 | +206,900+281.50% | Add |
| DIMENSIONAL FUND ADVISORS LP |
| <0.01% | <0.01% | #11 | $1.5M | 233,305 | $898,167 | 276,359 | -43,054-15.58% | Reduce |
| BOOTHBAY FUND MANAGEMENT, LLC |
| 0.01% | 0.01% | #2 | $729,285 | 112,544 | $415,006 | 127,694 | -15,150-11.86% | Reduce |
| JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #18 | $723,434 | 111,641 | $191,448 | 58,907 | +52,734+89.52% | Add |
| GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #21 | $702,616 | 108,413 | $371,499 | 114,293 | -5,880-5.14% | Reduce |
| PERCEPTIVE ADVISORS LLC |
| 0.01% | 0.01% | #3 | $628,443 | 96,982 | $640,179 | 196,978 | -99,996-50.77% | Reduce |
| CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #16 | $625,262 | 96,491 | $161,665 | 49,743 | +46,748+93.98% | Add |
| BlackRock, Inc. |
| <0.01% | <0.01% | #28 | $411,785 | 63,547 | $184,896 | 56,891 | +6,656+11.70% | Add |
| Bank of New York Mellon Corp |
| <0.01% | <0.01% | #17 | $378,807 | 58,458 | $189,988 | 58,458 | 00.00% | Unchanged |
| VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #15 | $355,810 | 54,909 | $148,275 | 45,623 | +9,286+20.35% | Add |
| STATE STREET CORP |
| <0.01% | <0.01% | #27 | $256,025 | 39,510 | $128,408 | 39,510 | 00.00% | Unchanged |
| UBS Group AG |
| <0.01% | <0.01% | #24 | $170,677 | 26,339 | $16,864 | 5,189 | +21,150+407.59% | Add |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC |
| <0.01% | 0.01% | #6 | $169,776 | 26,200 | $531,271 | 163,468 | -137,268-83.97% | Reduce |
| BAILARD, INC. |
| <0.01% | — | #5 | $159,564 | 24,624 | $0 | 0 | +24,624 | New Buy |
| Quadrature Capital Ltd |
| <0.01% | — | #7 | $155,611 | 24,014 | $0 | 0 | +24,014 | New Buy |
| TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #14 | $155,397 | 23,981 | $36,026 | 11,085 | +12,896+116.34% | Add |
| NORTHERN TRUST CORP |
| <0.01% | <0.01% | #26 | $142,255 | 21,953 | $63,710 | 19,603 | +2,350+11.99% | Add |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP |
| <0.01% | <0.01% | #19 | $131,233 | 20,252 | $65,819 | 20,252 | 00.00% | Unchanged |
| Cresset Asset Management, LLC |
| <0.01% | <0.01% | #9 | $126,198 | 19,475 | $63,294 | 19,475 | 00.00% | Unchanged |
| XTX Topco Ltd |
| <0.01% | <0.01% | #8 | $91,485 | 14,118 | $78,020 | 24,006 | -9,888-41.19% | Reduce |
| SIMPLEX TRADING, LLC |
| <0.01% | <0.01% | #25 | $29,445 | 4,544 | $23,075 | 7,100 | -2,556-36.00% | Reduce |
| GROUP ONE TRADING LLC |
| <0.01% | <0.01% | #22 | $25,920 | 4,000 | $22,425 | 6,900 | -2,900-42.03% | Reduce |
| MORGAN STANLEY |
| <0.01% | <0.01% | #30 | $21,131 | 3,261 | $11,247 | 3,605 | -344-9.54% | Reduce |
| Capital Advisors, Ltd. LLC |
| <0.01% | <0.01% | #10 | $2,832 | 437 | $1,000 | 437 | 00.00% | Unchanged |
| Institute for Wealth Management, LLC. |
| <0.01% | — | #12 | $2,285 | 352 | $0 | 0 | +352 | New Buy |
| OSAIC HOLDINGS, INC. |
| <0.01% | — | #29 | $1,296 | 200 | $0 | 0 | +200 | New Buy |
| Tower Research Capital LLC (TRC) |
| <0.01% | — | #23 | $1,238 | 191 | $0 | 0 | +191 | New Buy |
| WELLS FARGO & COMPANY/MN |
| <0.01% | <0.01% | #31 | $648 | 100 | $325 | 100 | 00.00% | Unchanged |
| BARCLAYS PLC |
| <0.01% | — | #32 | $311 | 48 | $0 | 0 | +48 | New Buy |
| FMR LLC |
| <0.01% | — | #34 | $136 | 21 | $0 | 0 | +21 | New Buy |
| HUNTINGTON NATIONAL BANK |
| <0.01% | <0.01% | #33 | $6 | 1 | $3 | 1 | 00.00% | Unchanged |
