| Soleus Capital Management, L.P. |
| 1.3% | 1.1% | #2 | $37.9M | 7.3M | $27.2M | 7.3M | 00.00% | Unchanged |
| MORGAN STANLEY |
| <0.01% | <0.01% | #20 | $17.3M | 3.3M | $7.7M | 3.4M | -24,908-0.74% | Reduce |
| Rock Springs Capital Management LP |
| 0.35% | 0.3% | #4 | $7.2M | 1.4M | $5.1M | 1.4M | +8,000+0.58% | Add |
| FLAX POND CAPITAL, LLC |
| 2.24% | 2.34% | #1 | $2.9M | 789,446 | $2.9M | 783,446 | +6,000+0.77% | Add |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #27 | $2.4M | 470,994 | $507,036 | 136,300 | +334,694+245.56% | Add |
| Bruce & Co., Inc. |
| 0.64% | 0.47% | #3 | $2.3M | 438,652 | $1.6M | 438,652 | 00.00% | Unchanged |
| JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #30 | $1.8M | 343,300 | $446,400 | 120,000 | +223,300+186.08% | Add |
| CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #29 | $1.3M | 256,083 | $340,380 | 91,500 | +164,583+179.87% | Add |
| Parkman Healthcare Partners LLC |
| 0.08% | 0.06% | #7 | $802,030 | 154,832 | $575,975 | 154,832 | 00.00% | Unchanged |
| ESSEX INVESTMENT MANAGEMENT CO LLC |
| 0.1% | — | #5 | $756,306 | 146,005 | $0 | 0 | +146,005 | New Buy |
| CAHILL FINANCIAL ADVISORS INC |
| 0.07% | 0.05% | #8 | $699,093 | 134,960 | $502,051 | 134,960 | 00.00% | Unchanged |
| US BANCORP \DE\ |
| <0.01% | <0.01% | #23 | $634,550 | 122,500 | $442,680 | 119,000 | +3,500+2.94% | Add |
| UBS Group AG |
| <0.01% | <0.01% | #33 | $613,286 | 118,395 | $631,024 | 169,630 | -51,235-30.20% | Reduce |
| Sage Mountain Advisors LLC |
| 0.03% | 0.03% | #11 | $518,000 | 100,000 | $372,000 | 100,000 | 00.00% | Unchanged |
| Leonteq Securities AG |
| 0.02% | 0.01% | #14 | $492,048 | 94,990 | $353,363 | 94,990 | 00.00% | Unchanged |
| Summit Trail Advisors, LLC |
| 0.01% | 0.01% | #15 | $426,516 | 82,339 | $380,701 | 102,339 | -20,000-19.54% | Reduce |
| Cetera Investment Advisers |
| <0.01% | <0.01% | #25 | $383,382 | 74,012 | $275,325 | 74,012 | 00.00% | Unchanged |
| COMMONWEALTH EQUITY SERVICES, LLC |
| <0.01% | <0.01% | #24 | $358,250 | 69,160 | $257,280 | 69,160 | 00.00% | Unchanged |
| Legato Capital Management LLC |
| 0.02% | — | #13 | $250,033 | 48,269 | $0 | 0 | +48,269 | New Buy |
| IMC-Chicago, LLC |
| <0.01% | <0.01% | #35 | $248,640 | 48,000 | $124,620 | 33,500 | +14,500+43.28% | Add |
| OSAIC HOLDINGS, INC. |
| <0.01% | <0.01% | #26 | $221,186 | 42,700 | $158,844 | 42,700 | 00.00% | Unchanged |
| Schonfeld Strategic Advisors LLC |
| <0.01% | <0.01% | #22 | $216,161 | 41,730 | $96,202 | 25,861 | +15,869+61.36% | Add |
| Manatuck Hill Partners, LLC |
| 0.05% | 0.03% | #9 | $142,952 | 27,597 | $102,661 | 27,597 | 00.00% | Unchanged |
| INTREPID FAMILY OFFICE LLC |
| 0.1% | 0.08% | #6 | $129,500 | 25,000 | $93,000 | 25,000 | 00.00% | Unchanged |
| SmartHarvest Portfolios, LLC |
| 0.04% | 0.02% | #10 | $123,973 | 23,933 | $37,646 | 10,120 | +13,813+136.49% | Add |
| SEI INVESTMENTS CO |
| <0.01% | — | #32 | $121,652 | 23,485 | $0 | 0 | +23,485 | New Buy |
| GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #39 | $117,917 | 22,764 | $84,682 | 22,764 | 00.00% | Unchanged |
| Accredited Investors Inc. |
| <0.01% | <0.01% | #16 | $111,013 | 21,431 | $79,723 | 21,431 | 00.00% | Unchanged |
| Mariner, LLC |
| <0.01% | — | #31 | $103,600 | 20,000 | $0 | 0 | +20,000 | New Buy |
| BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #36 | $96,374 | 18,605 | $85,951 | 23,105 | -4,500-19.48% | Reduce |
| Composition Wealth, LLC |
| <0.01% | <0.01% | #21 | $69,930 | 13,500 | $50,220 | 13,500 | 00.00% | Unchanged |
| Kovack Advisors, Inc. |
| <0.01% | <0.01% | #17 | $69,930 | 13,500 | $59,520 | 16,000 | -2,500-15.63% | Reduce |
| Simplicity Wealth,LLC |
| <0.01% | <0.01% | #19 | $63,533 | 12,265 | $41,385 | 11,125 | +1,140+10.25% | Add |
| Financial Planning Navigators CORP |
| 0.02% | 0.02% | #12 | $56,213 | 10,852 | $37,468 | 10,072 | +780+7.74% | Add |
| GROUP ONE TRADING LLC |
| <0.01% | <0.01% | #34 | $54,390 | 10,500 | $11,904 | 3,200 | +7,300+228.13% | Add |
| WELLS FARGO & COMPANY/MN |
| <0.01% | <0.01% | #38 | $48,816 | 9,424 | $13,020 | 3,500 | +5,924+169.26% | Add |
| RHUMBLINE ADVISERS |
| <0.01% | <0.01% | #37 | $22,955 | 4,432 | $11,314 | 3,042 | +1,390+45.69% | Add |
| VALLEY NATIONAL ADVISERS INC |
| <0.01% | <0.01% | #18 | $19,684 | 3,800 | $14,000 | 3,800 | 00.00% | Unchanged |
| HARBOR INVESTMENT ADVISORY, LLC |
| <0.01% | <0.01% | #28 | $2,590 | 500 | $1,860 | 500 | 00.00% | Unchanged |
| HARBOUR INVESTMENTS, INC. |
| <0.01% | <0.01% | #40 | $259 | 50 | $186 | 50 | 00.00% | Unchanged |
