| Sands Capital Alternatives, LLC |
| 4.31% | 5.19% | #2 | $26.4M | 13.0M | $21.9M | 13.0M | 00.00% | Unchanged |
| Soleus Capital Management, L.P. |
| 0.76% | 0.74% | #10 | $22.1M | 10.9M | $18.3M | 10.9M | 00.00% | Unchanged |
| Trails Edge Capital Partners, LP |
| 2.92% | 3.1% | #4 | $18.4M | 9.1M | $13.5M | 8.1M | +993,973+12.34% | Add |
| Fairmount Funds Management LLC |
| 1.16% | 1.05% | #7 | $17.5M | 8.6M | $14.5M | 8.6M | 00.00% | Unchanged |
| BlackRock, Inc. |
| <0.01% | <0.01% | #46 | $15.8M | 7.8M | $10.6M | 6.3M | +1.5M+23.24% | Add |
| ADAR1 Capital Management, LLC |
| 0.69% | 0.65% | #12 | $15.0M | 7.4M | $11.1M | 6.6M | +780,633+11.82% | Add |
| Blackstone Inc. |
| 0.04% | 0.04% | #23 | $12.1M | 5.9M | $10.0M | 5.9M | 00.00% | Unchanged |
| Siren, L.L.C. |
| 0.24% | 0.27% | #15 | $11.9M | 5.9M | $9.8M | 5.9M | 00.00% | Unchanged |
| Commodore Capital LP |
| 0.65% | 0.52% | #13 | $11.0M | 5.4M | $9.1M | 5.4M | 00.00% | Unchanged |
| VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #48 | $10.0M | 4.9M | $7.5M | 4.5M | +484,689+10.89% | Add |
| MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #28 | $8.2M | 4.0M | $4.9M | 2.9M | +1.1M+37.57% | Add |
| Saturn V Capital Management LP |
| 1.13% | 1.18% | #8 | $7.9M | 3.9M | $6.5M | 3.9M | +5,611+0.15% | Add |
| Kalehua Capital Management LLC |
| 5.56% | 4.54% | #1 | $7.8M | 3.8M | $6.4M | 3.8M | 00.00% | Unchanged |
| Spruce Street Capital LP |
| 1.43% | 1.45% | #6 | $7.3M | 3.6M | $6.0M | 3.6M | 00.00% | Unchanged |
| Squadron Capital Management LLC |
| 1.89% | 2.15% | #5 | $6.1M | 3.0M | $5.9M | 3.5M | -500,000-14.29% | Reduce |
| Nantahala Capital Management, LLC |
| 0.18% | 0.17% | #16 | $5.5M | 2.7M | $4.5M | 2.7M | 00.00% | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #43 | $5.3M | 2.6M | $3.6M | 2.2M | +436,943+20.13% | Add |
| Stonepine Capital Management, LLC |
| 0.75% | 0.64% | #11 | $4.9M | 2.5M | $1.6M | 957,202 | +1.5M+157.90% | Add |
| STATE STREET CORP |
| <0.01% | <0.01% | #55 | $3.9M | 1.9M | $2.8M | 1.7M | +223,285+13.24% | Add |
| SummitTX Capital, L.P. |
| 0.09% | 0.08% | #20 | $3.6M | 1.8M | $2.6M | 1.5M | +255,726+16.77% | Add |
| Integral Health Asset Management, LLC |
| 0.11% | 0.11% | #19 | $2.7M | 1.4M | $2.3M | 1.4M | 00.00% | Unchanged |
| NORTHERN TRUST CORP |
| <0.01% | <0.01% | #49 | $1.8M | 878,585 | $1.2M | 718,800 | +159,785+22.23% | Add |
| VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #65 | $1.6M | 809,490 | $1.0M | 617,730 | +191,760+31.04% | Add |
| TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #30 | $1.6M | 806,264 | $1.4M | 847,611 | -41,347-4.88% | Reduce |
| SPHERA FUNDS MANAGEMENT LTD. |
| 0.17% | — | #17 | $1.3M | 649,309 | $0 | 0 | +649,309 | New Buy |
| VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #44 | $1.2M | 607,260 | $952,558 | 566,999 | +40,261+7.10% | Add |
| Kennondale Capital Management LLC |
| 0.77% | — | #9 | $1.1M | 565,983 | $0 | 0 | +565,983 | New Buy |
| Pathstone Holdings, LLC |
| <0.01% | — | #27 | $1.0M | 510,596 | $0 | 0 | +510,596 | New Buy |
| AQR CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #42 | $950,440 | 468,197 | $288,982 | 172,013 | +296,184+172.19% | Add |
| Nuveen, LLC |
| <0.01% | <0.01% | #50 | $863,749 | 425,492 | $793,630 | 472,399 | -46,907-9.93% | Reduce |
| Seven Fleet Capital Management LP |
| 0.12% | 0.17% | #18 | $704,207 | 346,900 | $547,008 | 325,600 | +21,300+6.54% | Add |
| Bank of New York Mellon Corp |
| <0.01% | <0.01% | #56 | $615,346 | 303,126 | $358,189 | 213,208 | +89,918+42.17% | Add |
| JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #79 | $610,988 | 316,574 | $519,058 | 328,518 | -11,944-3.64% | Reduce |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #64 | $558,333 | 275,041 | $395,496 | 235,414 | +39,627+16.83% | Add |
| Rangeley Capital, LLC |
| 0.43% | 0.36% | #14 | $446,600 | 220,000 | $369,600 | 220,000 | 00.00% | Unchanged |
| UBS Group AG |
| <0.01% | <0.01% | #68 | $415,448 | 204,654 | $383,293 | 228,151 | -23,497-10.30% | Reduce |
| BLAIR WILLIAM & CO/IL |
| <0.01% | <0.01% | #34 | $316,842 | 156,080 | $265,420 | 157,988 | -1,908-1.21% | Reduce |
| ALPS ADVISORS INC |
| <0.01% | — | #29 | $272,024 | 134,002 | $0 | 0 | +134,002 | New Buy |
| DEUTSCHE BANK AG\ |
| <0.01% | <0.01% | #63 | $257,154 | 126,677 | $205,703 | 122,442 | +4,235+3.46% | Add |
| JONES FINANCIAL COMPANIES LLLP |
| <0.01% | <0.01% | #57 | $245,418 | 128,491 | $54,096 | 32,200 | +96,291+299.04% | Add |
| RHUMBLINE ADVISERS |
| <0.01% | <0.01% | #51 | $243,622 | 120,014 | $98,639 | 58,717 | +61,297+104.39% | Add |
| MORGAN STANLEY |
| <0.01% | <0.01% | #91 | $231,432 | 114,006 | $90,753 | 56,019 | +57,987+103.51% | Add |
| BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #88 | $219,288 | 108,024 | $542,143 | 322,704 | -214,680-66.53% | Reduce |
| FMR LLC |
| <0.01% | <0.01% | #95 | $210,566 | 103,727 | $120,898 | 71,963 | +31,764+44.14% | Add |
| WELLS FARGO & COMPANY/MN |
| <0.01% | <0.01% | #80 | $206,737 | 101,841 | $68,092 | 40,531 | +61,310+151.27% | Add |
| PRICE T ROWE ASSOCIATES INC /MD/ |
| <0.01% | <0.01% | #86 | $202,253 | 99,632 | $86,000 | 50,874 | +48,758+95.84% | Add |
| CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #87 | $150,928 | 74,349 | $1.9M | 1.1M | -1.0M-93.26% | Reduce |
| IEQ CAPITAL, LLC |
| <0.01% | <0.01% | #36 | $139,078 | 68,511 | $26,623 | 15,847 | +52,664+332.33% | Add |
| MetLife Investment Management, LLC |
| <0.01% | <0.01% | #40 | $126,924 | 62,524 | $105,694 | 62,913 | -389-0.62% | Reduce |
| Invesco Ltd. |
| <0.01% | <0.01% | #92 | $126,069 | 62,103 | $57,719 | 34,357 | +27,746+80.76% | Add |
