| BlackRock, Inc. |
| 0.01% | 0.01% | #210 | $501.7M | 46.2M | $477.9M | 43.1M | +3.1M+7.19% | Add |
| Tetragon Partners GP Ltd |
| 52.98% | 54.32% | #1 | $336.4M | 31.0M | $279.8M | 25.2M | +5.7M+22.78% | Add |
| VANGUARD PORTFOLIO MANAGEMENT LLC |
| 0.01% | 0.02% | #168 | $286.1M | 26.3M | $294.0M | 26.5M | -168,163-0.63% | Reduce |
| VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | 0.01% | #268 | $203.4M | 18.7M | $206.4M | 18.6M | +115,820+0.62% | Add |
| TWO SIGMA INVESTMENTS, LP |
| 0.12% | 0.03% | #49 | $163.4M | 15.0M | $39.5M | 3.6M | +11.5M+322.39% | Add |
| STATE STREET CORP |
| <0.01% | 0.01% | #265 | $150.4M | 13.8M | $148.1M | 13.3M | +486,007+3.64% | Add |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| 0.01% | 0.02% | #182 | $147.4M | 13.6M | $158.6M | 14.3M | -725,933-5.08% | Reduce |
| GOLDMAN SACHS GROUP INC |
| 0.01% | 0.01% | #175 | $139.1M | 12.8M | $75.6M | 6.8M | +6.0M+88.02% | Add |
| Senvest Management, LLC |
| 3.85% | 2.87% | #5 | $131.4M | 12.1M | $86.4M | 7.8M | +4.3M+55.24% | Add |
| BANK OF AMERICA CORP /DE/ |
| 0.01% | 0.01% | #205 | $122.7M | 11.3M | $111.5M | 10.0M | +1.2M+12.40% | Add |
| UBS Group AG |
| 0.01% | 0.02% | #181 | $90.5M | 8.3M | $111.7M | 10.1M | -1.7M-17.27% | Reduce |
| GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | 0.01% | #256 | $88.7M | 8.2M | $89.4M | 8.1M | +104,690+1.30% | Add |
| DIMENSIONAL FUND ADVISORS LP |
| 0.02% | 0.02% | #150 | $86.7M | 8.0M | $75.8M | 6.8M | +1.1M+16.75% | Add |
| JANE STREET GROUP, LLC |
| 0.01% | 0.02% | #215 | $85.1M | 7.8M | $177.0M | 15.9M | -8.1M-50.87% | Reduce |
| MORGAN STANLEY |
| <0.01% | <0.01% | #266 | $83.2M | 7.7M | $80.9M | 6.0M | +1.6M+26.62% | Add |
| JUPITER ASSET MANAGEMENT LTD |
| 0.41% | 0.14% | #21 | $82.2M | 7.6M | $25.6M | 2.3M | +5.3M+227.41% | Add |
| Alphabet Inc. |
| 1.82% | 1.94% | #7 | $78.1M | 7.0M | $78.1M | 7.0M | 00.00% | Unchanged |
| CITADEL ADVISORS LLC |
| 0.01% | 0.01% | #197 | $78.1M | 7.2M | $79.9M | 7.2M | -15,305-0.21% | Reduce |
| FEDERATED HERMES, INC. |
| 0.11% | 0.12% | #54 | $76.7M | 7.1M | $74.6M | 6.7M | +340,097+5.06% | Add |
| D. E. Shaw & Co., Inc. |
| 0.03% | 0.01% | #109 | $69.3M | 6.4M | $13.0M | 1.2M | +5.2M+444.81% | Add |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
| 0.07% | 0.08% | #68 | $59.3M | 5.5M | $58.4M | 5.3M | +189,881+3.61% | Add |
| NORGES BANK |
| 0.01% | 0.01% | #245 | $52.0M | 4.8M | $39.5M | 3.8M | +954,051+24.90% | Add |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| 0.01% | 0.01% | #231 | $43.5M | 4.0M | $45.3M | 4.1M | -73,016-1.79% | Reduce |
| RENAISSANCE TECHNOLOGIES LLC |
| 0.05% | — | #85 | $38.6M | 3.6M | $0 | 0 | +3.6M | New Buy |
| Neuberger Berman Group LLC |
| 0.02% | 0.03% | #122 | $35.5M | 3.3M | $33.9M | 3.1M | +205,705+6.72% | Add |
| NORTHERN TRUST CORP |
| <0.01% | <0.01% | #276 | $35.1M | 3.2M | $35.6M | 3.2M | +14,805+0.46% | Add |
| JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #340 | $31.1M | 2.9M | $16.8M | 1.5M | +1.4M+87.82% | Add |
| Bank of New York Mellon Corp |
| 0.01% | 0.01% | #250 | $30.7M | 2.8M | $34.4M | 3.1M | -270,895-8.75% | Reduce |
| VANGUARD FIDUCIARY TRUST CO |
| 0.01% | 0.01% | #221 | $29.2M | 2.7M | $29.4M | 2.6M | +39,959+1.51% | Add |
| MILLENNIUM MANAGEMENT LLC |
| 0.01% | 0.01% | #191 | $28.8M | 2.7M | $29.5M | 2.7M | -7,661-0.29% | Reduce |
| ALKEON CAPITAL MANAGEMENT LLC |
| 0.04% | 0.05% | #101 | $28.4M | 2.6M | $29.0M | 2.6M | 00.00% | Unchanged |
| CANADA LIFE ASSURANCE Co |
| 0.04% | 0.05% | #95 | $27.6M | 2.5M | $26.9M | 2.4M | +124,490+5.15% | Add |
| FIRST TRUST ADVISORS LP |
| 0.01% | 0.01% | #153 | $24.6M | 2.3M | $18.0M | 1.6M | +640,687+39.45% | Add |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP |
| 0.01% | <0.01% | #190 | $22.3M | 2.0M | $1.8M | 166,052 | +1.9M+1,134.22% | Add |
| PEAK6 LLC |
| 0.04% | 0.08% | #93 | $21.9M | 2.0M | $34.0M | 3.1M | -1.0M-34.30% | Reduce |
| ARMISTICE CAPITAL, LLC |
| 0.27% | 0.25% | #28 | $21.7M | 2.0M | $14.3M | 1.3M | +715,280+55.68% | Add |
| COATUE MANAGEMENT LLC |
| 0.04% | 0.09% | #96 | $21.3M | 2.0M | $25.2M | 2.3M | -308,192-13.58% | Reduce |
| Invenomic Capital Management LP |
| 1.16% | 0.83% | #11 | $19.4M | 1.8M | $18.2M | 1.6M | +150,688+9.21% | Add |
| AQR CAPITAL MANAGEMENT LLC |
| 0.01% | 0.01% | #218 | $19.4M | 1.8M | $31.3M | 2.8M | -1.0M-36.40% | Reduce |
| BALYASNY ASSET MANAGEMENT L.P. |
| 0.02% | — | #127 | $17.8M | 1.6M | $0 | 0 | +1.6M | New Buy |
| Symmetry Investments LP |
| 1.17% | 2.74% | #10 | $17.2M | 1.6M | $25.0M | 2.3M | -665,914-29.57% | Reduce |
| Gotham Asset Management, LLC |
| 0.04% | 0.02% | #100 | $16.8M | 1.5M | $6.5M | 581,400 | +968,573+166.59% | Add |
| Squarepoint Ops LLC |
| 0.02% | <0.01% | #140 | $16.3M | 1.5M | $208,680 | 18,800 | +1.5M+7,865.72% | Add |
| CITIGROUP INC |
| 0.01% | <0.01% | #244 | $16.1M | 1.5M | $5.6M | 503,124 | +976,500+194.09% | Add |
| Pacer Advisors, Inc. |
| 0.04% | <0.01% | #97 | $14.3M | 1.3M | $586,000 | 52,813 | +1.3M+2,388.71% | Add |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
| <0.01% | <0.01% | #318 | $13.5M | 1.2M | $12.4M | 1.1M | +125,770+11.30% | Add |
| Man Group plc |
| 0.02% | 0.01% | #130 | $13.4M | 1.2M | $6.1M | 553,718 | +682,048+123.18% | Add |
| BNP PARIBAS FINANCIAL MARKETS |
| 0.01% | <0.01% | #223 | $13.1M | 1.0M | $8.9M | 604,921 | +399,185+65.99% | Add |
| AMERIPRISE FINANCIAL INC |
| <0.01% | <0.01% | #311 | $12.9M | 1.2M | $13.9M | 1.3M | -63,400-5.06% | Reduce |
| Nuveen, LLC |
| <0.01% | <0.01% | #297 | $12.9M | 1.2M | $11.2M | 1.0M | +176,006+17.47% | Add |
