| BlackRock, Inc. |
| 0.02% | 0.02% | #125 | $1.14B | 14.0M | $882.2M | 12.9M | +1.0M+7.85% | Add |
| RTW INVESTMENTS, LP |
| 5.39% | 5.25% | #3 | $631.9M | 7.7M | $527.8M | 7.7M | 00.00% | Unchanged |
| Jupiter Topco LLC |
| 0.24% | — | #31 | $590.2M | 7.2M | $0 | 0 | +7.2M | New Buy |
| VANGUARD PORTFOLIO MANAGEMENT LLC |
| 0.02% | 0.02% | #116 | $402.0M | 4.9M | $327.3M | 4.8M | +123,517+2.57% | Add |
| STATE STREET CORP |
| 0.01% | 0.01% | #146 | $375.1M | 4.6M | $296.1M | 4.3M | +252,433+5.81% | Add |
| WELLINGTON MANAGEMENT GROUP LLP |
| 0.06% | 0.05% | #69 | $336.7M | 4.1M | $268.6M | 3.9M | +185,663+4.71% | Add |
| VANGUARD CAPITAL MANAGEMENT LLC |
| 0.01% | 0.01% | #186 | $305.0M | 3.7M | $250.5M | 3.7M | +62,871+1.71% | Add |
| GEODE CAPITAL MANAGEMENT, LLC |
| 0.01% | 0.01% | #153 | $180.1M | 2.2M | $150.6M | 2.2M | -2,578-0.12% | Reduce |
| TORONTO DOMINION BANK |
| 0.2% | 0.3% | #34 | $176.7M | 2.2M | $206.2M | 3.0M | -860,117-28.42% | Reduce |
| WESTFIELD CAPITAL MANAGEMENT CO LP |
| 0.52% | — | #19 | $159.6M | 2.0M | $0 | 0 | +2.0M | New Buy |
| Hood River Capital Management LLC |
| 1.03% | 1.14% | #9 | $141.8M | 1.7M | $113.4M | 1.7M | +74,054+4.45% | Add |
| ARMISTICE CAPITAL, LLC |
| 1.73% | 2.99% | #7 | $141.2M | 1.7M | $167.9M | 2.5M | -733,054-29.75% | Reduce |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC |
| 0.42% | — | #21 | $140.5M | 1.7M | $0 | 0 | +1.7M | New Buy |
| D. E. Shaw & Co., Inc. |
| 0.06% | 0.07% | #66 | $126.3M | 1.5M | $111.8M | 1.6M | -91,462-5.58% | Reduce |
| TANG CAPITAL MANAGEMENT LLC |
| 5.56% | 5.19% | #2 | $122.4M | 1.5M | $102.2M | 1.5M | 00.00% | Unchanged |
| BANK OF AMERICA CORP /DE/ |
| 0.01% | 0.01% | #169 | $118.5M | 1.5M | $128.6M | 1.9M | -434,564-23.03% | Reduce |
| DRIEHAUS CAPITAL MANAGEMENT LLC |
| 0.68% | 0.51% | #12 | $117.5M | 1.4M | $69.2M | 1.0M | +424,335+41.77% | Add |
| FMR LLC |
| <0.01% | 0.01% | #207 | $114.1M | 1.4M | $104.1M | 1.5M | -130,101-8.51% | Reduce |
| Jefferies Financial Group Inc. |
| 0.73% | 0.63% | #11 | $110.7M | 1.4M | $92.3M | 1.4M | +2,583+0.19% | Add |
| FULLER & THALER ASSET MANAGEMENT, INC. |
| 0.26% | — | #30 | $94.4M | 1.2M | $0 | 0 | +1.2M | New Buy |
| Pictet Asset Management Holding SA |
| 0.09% | 0.08% | #48 | $93.6M | 1.1M | $80.1M | 1.2M | -35,876-3.03% | Reduce |
| PRICE T ROWE ASSOCIATES INC /MD/ |
| 0.01% | <0.01% | #157 | $90.9M | 1.1M | $32.4M | 475,148 | +639,368+134.56% | Add |
| MORGAN STANLEY |
| <0.01% | <0.01% | #212 | $90.0M | 1.1M | $25.7M | 419,417 | +684,258+163.15% | Add |
| Blue Sparrow, LLC /DE |
| 0.83% | 0.22% | #10 | $85.7M | 1.1M | $13.0M | 190,600 | +860,100+451.26% | Add |
| FRANKLIN RESOURCES INC |
| 0.02% | 0.02% | #121 | $83.8M | 1.0M | $76.4M | 1.1M | -94,061-8.39% | Reduce |
| Invesco Ltd. |
| 0.01% | 0.01% | #192 | $76.8M | 941,581 | $59.0M | 865,451 | +76,130+8.80% | Add |
| Palo Alto Investors LP |
| 10.95% | 9.6% | #1 | $75.0M | 918,846 | $62.8M | 921,607 | -2,761-0.30% | Reduce |
| NORTHERN TRUST CORP |
| 0.01% | 0.01% | #161 | $71.8M | 880,029 | $54.9M | 806,276 | +73,753+9.15% | Add |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| 0.01% | 0.01% | #159 | $64.4M | 790,112 | $49.8M | 731,642 | +58,470+7.99% | Add |
| CITADEL ADVISORS LLC |
| 0.01% | <0.01% | #175 | $62.5M | 766,822 | $28.2M | 413,499 | +353,323+85.45% | Add |
| RENAISSANCE TECHNOLOGIES LLC |
| 0.08% | 0.06% | #54 | $59.0M | 723,500 | $36.3M | 533,300 | +190,200+35.66% | Add |
| Boston Partners |
| 0.05% | 0.05% | #73 | $58.6M | 718,574 | $44.1M | 647,482 | +71,092+10.98% | Add |
| JUPITER ASSET MANAGEMENT LTD |
| 0.29% | 0.26% | #26 | $57.7M | 707,450 | $48.5M | 711,457 | -4,007-0.56% | Reduce |
| MARSHALL WACE, LLP |
| 0.05% | 0.03% | #77 | $57.5M | 704,787 | $31.4M | 460,638 | +244,149+53.00% | Add |
| JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #232 | $56.1M | 684,042 | $22.7M | 346,017 | +338,025+97.69% | Add |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP |
| 0.02% | <0.01% | #103 | $53.4M | 654,382 | $7.6M | 111,632 | +542,750+486.20% | Add |
| DIMENSIONAL FUND ADVISORS LP |
| 0.01% | 0.01% | #156 | $52.0M | 637,704 | $60.7M | 890,715 | -253,011-28.41% | Reduce |
| GOLDMAN SACHS GROUP INC |
| <0.01% | 0.01% | #217 | $50.4M | 618,247 | $56.4M | 827,631 | -209,384-25.30% | Reduce |
| SG Americas Securities, LLC |
| 0.02% | 0.07% | #102 | $49.4M | 605,581 | $59.9M | 879,701 | -274,120-31.16% | Reduce |
| LOOMIS SAYLES & CO L P |
| 0.06% | 0.05% | #65 | $48.2M | 590,374 | $33.6M | 493,603 | +96,771+19.61% | Add |
| LORD, ABBETT & CO. LLC |
| 0.14% | 0.14% | #44 | $48.1M | 590,074 | $42.0M | 617,121 | -27,047-4.38% | Reduce |
| VANGUARD FIDUCIARY TRUST CO |
| 0.01% | 0.01% | #147 | $48.0M | 587,887 | $37.7M | 553,658 | +34,229+6.18% | Add |
| Nuveen, LLC |
| 0.01% | 0.01% | #145 | $47.6M | 583,829 | $45.4M | 667,019 | -83,190-12.47% | Reduce |
| Bank of New York Mellon Corp |
| 0.01% | 0.01% | #172 | $45.1M | 553,462 | $35.6M | 522,763 | +30,699+5.87% | Add |
| PRINCIPAL FINANCIAL GROUP INC |
| 0.02% | 0.02% | #110 | $44.2M | 541,635 | $35.1M | 515,001 | +26,634+5.17% | Add |
| VOYA INVESTMENT MANAGEMENT LLC |
| 0.04% | 0.02% | #83 | $44.0M | 539,319 | $23.3M | 342,637 | +196,682+57.40% | Add |
| Ensign Peak Advisors, Inc |
| 0.07% | 0.07% | #60 | $41.4M | 508,056 | $39.7M | 582,318 | -74,262-12.75% | Reduce |
| AMERICAN CENTURY COMPANIES INC |
| 0.02% | <0.01% | #117 | $40.9M | 500,995 | $340,854 | 5,003 | +495,992+9,913.89% | Add |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #230 | $40.8M | 500,262 | $24.7M | 362,938 | +137,324+37.84% | Add |
| FEDERATED HERMES, INC. |
| 0.06% | 0.03% | #71 | $39.4M | 483,424 | $15.4M | 225,916 | +257,508+113.98% | Add |
