| BlackRock, Inc. |
| 0.02% | 0.01% | #120 | $1.08B | 12.4M | $489.8M | 12.2M | +280,747+2.31% | Add |
| INGALLS & SNYDER LLC |
| 18.86% | 10.86% | #1 | $691.0M | 7.9M | $306.8M | 7.6M | +335,091+4.40% | Add |
| RENAISSANCE TECHNOLOGIES LLC |
| 0.63% | 0.36% | #17 | $457.5M | 5.3M | $229.1M | 5.7M | -421,155-7.41% | Reduce |
| VANGUARD PORTFOLIO MANAGEMENT LLC |
| 0.02% | 0.01% | #112 | $438.6M | 5.0M | $194.3M | 4.8M | +224,070+4.65% | Add |
| VANGUARD CAPITAL MANAGEMENT LLC |
| 0.01% | <0.01% | #195 | $362.8M | 4.2M | $164.4M | 4.1M | +95,286+2.34% | Add |
| Parallel Advisors, LLC |
| 5.25% | 2.88% | #4 | $344.5M | 4.0M | $160.3M | 4.0M | -15,227-0.38% | Reduce |
| FMR LLC |
| 0.01% | 0.01% | #145 | $290.2M | 3.3M | $128.6M | 3.2M | +147,426+4.62% | Add |
| STATE STREET CORP |
| 0.01% | <0.01% | #188 | $285.2M | 3.3M | $129.0M | 3.2M | +78,435+2.45% | Add |
| AQR CAPITAL MANAGEMENT LLC |
| 0.08% | 0.01% | #59 | $224.6M | 2.6M | $15.9M | 406,205 | +2.2M+535.78% | Add |
| GEODE CAPITAL MANAGEMENT, LLC |
| 0.01% | 0.01% | #152 | $220.2M | 2.5M | $109.4M | 2.7M | -181,321-6.68% | Reduce |
| FIRST TRUST ADVISORS LP |
| 0.09% | 0.06% | #53 | $159.1M | 1.8M | $87.6M | 2.2M | -343,831-15.82% | Reduce |
| TANG CAPITAL MANAGEMENT LLC |
| 5.92% | 3.07% | #3 | $130.4M | 1.5M | $60.5M | 1.5M | 00.00% | Unchanged |
| UBS Group AG |
| 0.02% | 0.01% | #125 | $119.8M | 1.4M | $55.0M | 1.4M | +13,990+1.03% | Add |
| DIMENSIONAL FUND ADVISORS LP |
| 0.02% | 0.01% | #108 | $114.7M | 1.3M | $62.6M | 1.6M | -234,314-15.09% | Reduce |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| 0.01% | 0.01% | #141 | $100.7M | 1.2M | $45.1M | 1.1M | +37,621+3.36% | Add |
| MORGAN STANLEY |
| 0.01% | 0.01% | #219 | $98.9M | 1.1M | $98.6M | 1.2M | -49,419-4.16% | Reduce |
| D. E. Shaw & Co., Inc. |
| 0.04% | 0.03% | #85 | $76.8M | 883,001 | $47.6M | 1.2M | -298,347-25.25% | Reduce |
| Cerity Partners LLC |
| 0.08% | 0.04% | #56 | $69.3M | 797,119 | $29.5M | 731,689 | +65,430+8.94% | Add |
| MPM BioImpact LLC |
| 4.09% | 3.07% | #5 | $67.0M | 771,028 | $39.7M | 985,700 | -214,672-21.78% | Reduce |
| NORTHERN TRUST CORP |
| 0.01% | <0.01% | #196 | $65.5M | 753,796 | $25.9M | 643,158 | +110,638+17.20% | Add |
| EMERALD ADVISERS, LLC |
| 1.53% | 0.26% | #10 | $65.1M | 748,325 | $8.3M | 205,558 | +542,767+264.05% | Add |
| FULLER & THALER ASSET MANAGEMENT, INC. |
| 0.17% | — | #38 | $61.7M | 710,106 | $0 | 0 | +710,106 | New Buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC |
| 0.22% | — | #33 | $60.5M | 695,532 | $0 | 0 | +695,532 | New Buy |
| VANGUARD FIDUCIARY TRUST CO |
| 0.01% | 0.01% | #151 | $53.4M | 614,078 | $23.8M | 590,307 | +23,771+4.03% | Add |
| TWO SIGMA INVESTMENTS, LP |
| 0.04% | 0.03% | #82 | $53.0M | 610,078 | $38.1M | 945,884 | -335,806-35.50% | Reduce |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #246 | $50.6M | 582,184 | $36.5M | 905,831 | -323,647-35.73% | Reduce |
| GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #231 | $50.3M | 578,519 | $29.3M | 725,822 | -147,303-20.29% | Reduce |
| Caption Management, LLC |
| 0.23% | 0.33% | #32 | $49.4M | 568,000 | $57.0M | 1.4M | -847,100-59.86% | Reduce |
| Bank of New York Mellon Corp |
| 0.01% | <0.01% | #191 | $49.2M | 565,666 | $21.9M | 543,757 | +21,909+4.03% | Add |
| Allspring Global Investments Holdings, LLC |
| 0.07% | 0.02% | #63 | $46.3M | 523,192 | $9.0M | 214,572 | +308,620+143.83% | Add |
| Invesco Ltd. |
| <0.01% | <0.01% | #254 | $45.5M | 523,669 | $25.3M | 628,384 | -104,715-16.66% | Reduce |
| NORGES BANK |
| <0.01% | 0.01% | #237 | $42.3M | 487,055 | $97.0M | 848,897 | -361,842-42.62% | Reduce |
| EMERALD MUTUAL FUND ADVISERS TRUST |
| 1.42% | 0.35% | #14 | $40.4M | 464,902 | $7.2M | 179,607 | +285,295+158.84% | Add |
| PRINCIPAL FINANCIAL GROUP INC |
| 0.02% | 0.01% | #113 | $40.0M | 459,742 | $18.4M | 455,248 | +4,494+0.99% | Add |
| Boston Trust Walden Corp |
| 0.29% | 0.15% | #28 | $38.3M | 440,264 | $18.6M | 462,606 | -22,342-4.83% | Reduce |
| CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #236 | $37.0M | 425,705 | $22.0M | 544,620 | -118,915-21.83% | Reduce |
| PERCEPTIVE ADVISORS LLC |
| 0.52% | 0.04% | #19 | $34.6M | 398,385 | $2.0M | 50,000 | +348,385+696.77% | Add |
| Nuveen, LLC |
| 0.01% | <0.01% | #192 | $33.7M | 388,078 | $7.7M | 191,904 | +196,174+102.23% | Add |
| Boxer Capital Management, LLC |
| 2.2% | 1.32% | #8 | $29.2M | 335,500 | $10.1M | 250,000 | +85,500+34.20% | Add |
| BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #296 | $28.6M | 328,565 | $4.5M | 111,736 | +216,829+194.05% | Add |
| PUBLIC SECTOR PENSION INVESTMENT BOARD |
| 0.07% | 0.04% | #61 | $28.5M | 328,224 | $13.5M | 334,875 | -6,651-1.99% | Reduce |
| FAS Wealth Partners, Inc. |
| 1.47% | 0.81% | #11 | $28.2M | 324,876 | $13.0M | 322,370 | +2,506+0.78% | Add |
| JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #320 | $22.7M | 253,182 | $7.7M | 200,953 | +52,229+25.99% | Add |
| CITIGROUP INC |
| 0.01% | 0.01% | #204 | $20.7M | 237,609 | $17.0M | 421,067 | -183,458-43.57% | Reduce |
| Legal & General Group Plc |
| <0.01% | <0.01% | #243 | $19.0M | 218,078 | $8.9M | 219,680 | -1,602-0.73% | Reduce |
| MILLENNIUM MANAGEMENT LLC |
| 0.01% | 0.01% | #209 | $18.8M | 216,167 | $22.5M | 558,747 | -342,580-61.31% | Reduce |
| AMERIPRISE FINANCIAL INC |
| <0.01% | <0.01% | #250 | $18.4M | 212,162 | $8.5M | 212,074 | +88+0.04% | Add |
| FRANKLIN RESOURCES INC |
| <0.01% | <0.01% | #248 | $18.4M | 212,029 | $12.3M | 305,211 | -93,182-30.53% | Reduce |
| Susquehanna Portfolio Strategies, LLC |
| 0.29% | 0.11% | #27 | $18.3M | 211,017 | $7.1M | 177,147 | +33,870+19.12% | Add |
| DIADEMA PARTNERS LP |
| 2.21% | 1.16% | #7 | $17.9M | 206,300 | $6.8M | 168,500 | +37,800+22.43% | Add |
