| WASATCH ADVISORS LP |
| 0.13% | 0.07% | #9 | $20.2M | 2.9M | $10.0M | 2.1M | +725,560+34.01% | Add |
| TANG CAPITAL MANAGEMENT LLC |
| 0.52% | 0.38% | #1 | $11.4M | 1.6M | $7.6M | 1.6M | 00.00% | Unchanged |
| VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #40 | $4.8M | 675,185 | $5.1M | 1.1M | -406,895-37.60% | Reduce |
| PUNCH & ASSOCIATES INVESTMENT MANAGEMENT, INC. |
| 0.19% | — | #8 | $3.8M | 536,000 | $0 | 0 | +536,000 | New Buy |
| Pale Fire Capital SE |
| 0.26% | 0.2% | #4 | $3.7M | 528,584 | $2.3M | 481,987 | +46,597+9.67% | Add |
| Opaleye Management Inc. |
| 0.22% | 0.59% | #5 | $2.5M | 350,000 | $4.5M | 960,000 | -610,000-63.54% | Reduce |
| JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #36 | $2.5M | 348,421 | $129,913 | 27,700 | +320,721+1,157.84% | Add |
| Summit Financial, LLC |
| 0.03% | 0.02% | #11 | $2.5M | 346,748 | $1.8M | 379,807 | -33,059-8.70% | Reduce |
| Diametric Capital, LP |
| 0.22% | 0.24% | #6 | $2.1M | 295,663 | $921,172 | 196,412 | +99,251+50.53% | Add |
| Ikarian Capital, LLC |
| 0.19% | 0.1% | #7 | $1.8M | 251,436 | $1.2M | 251,436 | 00.00% | Unchanged |
| RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #24 | $1.6M | 229,700 | $1.1M | 242,500 | -12,800-5.28% | Reduce |
| GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #42 | $1.5M | 216,004 | $2.2M | 463,202 | -247,198-53.37% | Reduce |
| AMERICAN FINANCIAL GROUP INC |
| 0.45% | 0.31% | #2 | $1.3M | 180,000 | $844,200 | 180,000 | 00.00% | Unchanged |
| Trexquant Investment LP |
| 0.01% | <0.01% | #19 | $1.2M | 171,338 | $131,770 | 28,096 | +143,242+509.83% | Add |
| MARSHALL WACE, LLP |
| <0.01% | — | #31 | $990,087 | 139,843 | $0 | 0 | +139,843 | New Buy |
| J. Goldman & Co LP |
| 0.03% | 0.07% | #12 | $974,095 | 137,584 | $2.3M | 500,188 | -362,604-72.49% | Reduce |
| MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #35 | $778,913 | 110,016 | $1.8M | 383,067 | -273,051-71.28% | Reduce |
| BlackRock, Inc. |
| <0.01% | <0.01% | #59 | $714,945 | 100,981 | $4.6M | 972,862 | -871,881-89.62% | Reduce |
| XTX Topco Ltd |
| 0.01% | <0.01% | #17 | $714,535 | 100,923 | $137,717 | 29,364 | +71,559+243.70% | Add |
| VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #38 | $670,681 | 94,729 | $645,841 | 137,706 | -42,977-31.21% | Reduce |
| GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #48 | $639,282 | 90,294 | $325,434 | 69,389 | +20,905+30.13% | Add |
| UBS Group AG |
| <0.01% | <0.01% | #43 | $591,279 | 83,514 | $1.8M | 390,138 | -306,624-78.59% | Reduce |
| CITADEL ADVISORS LLC |
| <0.01% | — | #45 | $581,615 | 82,149 | $0 | 0 | +82,149 | New Buy |
| PVG ASSET MANAGEMENT CORP |
| 0.33% | 0.3% | #3 | $563,377 | 79,573 | $505,697 | 79,763 | -190-0.24% | Reduce |
| Integrated Wealth Concepts LLC |
| <0.01% | <0.01% | #23 | $558,809 | 78,928 | $189,332 | 40,369 | +38,559+95.52% | Add |
| BOOTHBAY FUND MANAGEMENT, LLC |
| 0.01% | <0.01% | #20 | $477,489 | 67,442 | $316,303 | 67,442 | 00.00% | Unchanged |
| STATE STREET CORP |
| <0.01% | <0.01% | #56 | $467,124 | 65,978 | $1.1M | 237,288 | -171,310-72.19% | Reduce |
| ENVESTNET ASSET MANAGEMENT INC |
| <0.01% | <0.01% | #39 | $466,041 | 65,825 | $335,973 | 71,636 | -5,811-8.11% | Reduce |
| Walleye Capital LLC |
| <0.01% | — | #27 | $463,471 | 65,462 | $0 | 0 | +65,462 | New Buy |
| Geneos Wealth Management Inc. |
| 0.01% | — | #18 | $448,022 | 63,280 | $0 | 0 | +63,280 | New Buy |
| Arete Wealth Advisors, LLC |
| 0.01% | — | #15 | $366,687 | 51,792 | $0 | 0 | +51,792 | New Buy |
| Frec Markets, Inc. |
| 0.03% | 0.04% | #10 | $357,540 | 50,500 | $236,845 | 50,500 | 00.00% | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #37 | $335,670 | 47,411 | $21,808 | 4,650 | +42,761+919.59% | Add |
| Squarepoint Ops LLC |
| <0.01% | <0.01% | #34 | $321,467 | 45,405 | $76,907 | 16,398 | +29,007+176.89% | Add |
| MORGAN STANLEY |
| <0.01% | <0.01% | #54 | $297,530 | 42,024 | $147,612 | 20,732 | +21,292+102.70% | Add |
| BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #52 | $296,701 | 41,907 | $151,046 | 32,206 | +9,701+30.12% | Add |
| ADAR1 Capital Management, LLC |
| 0.01% | — | #14 | $279,780 | 39,517 | $0 | 0 | +39,517 | New Buy |
| STATE OF WISCONSIN INVESTMENT BOARD |
| <0.01% | <0.01% | #33 | $254,200 | 35,904 | $209,662 | 44,704 | -8,800-19.69% | Reduce |
| NORTHERN TRUST CORP |
| <0.01% | <0.01% | #50 | $252,444 | 35,656 | $703,397 | 149,978 | -114,322-76.23% | Reduce |
| SALEM INVESTMENT COUNSELORS INC |
| 0.01% | <0.01% | #21 | $206,736 | 29,200 | $67,067 | 14,300 | +14,900+104.20% | Add |
| Quadrature Capital Ltd |
| <0.01% | — | #25 | $204,194 | 28,841 | $0 | 0 | +28,841 | New Buy |
| AQR CAPITAL MANAGEMENT LLC |
| <0.01% | — | #47 | $176,129 | 24,877 | $0 | 0 | +24,877 | New Buy |
| PRELUDE CAPITAL MANAGEMENT, LLC |
| 0.01% | 0.01% | #16 | $155,087 | 21,905 | $140,203 | 29,894 | -7,989-26.72% | Reduce |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #57 | $141,607 | 20,001 | $59,661 | 12,721 | +7,280+57.23% | Add |
| Gladstone Institutional Advisory LLC |
| <0.01% | <0.01% | #22 | $141,600 | 20,000 | $124,618 | 26,571 | -6,571-24.73% | Reduce |
| Brevan Howard Capital Management LP |
| <0.01% | — | #30 | $133,508 | 18,857 | $0 | 0 | +18,857 | New Buy |
| Invesco Ltd. |
| <0.01% | <0.01% | #62 | $118,087 | 16,679 | $86,746 | 18,496 | -1,817-9.82% | Reduce |
| Jefferies Financial Group Inc. |
| <0.01% | — | #32 | $117,507 | 16,597 | $0 | 0 | +16,597 | New Buy |
| Mariner, LLC |
| <0.01% | — | #41 | $94,505 | 13,348 | $0 | 0 | +13,348 | New Buy |
| BRIGHTON JONES LLC |
| <0.01% | — | #26 | $89,931 | 12,702 | $0 | 0 | +12,702 | New Buy |
