| Curative Ventures V LLC |
| 100% | 100% | #1 | $14.6M | 1.9M | $15.6M | 1.9M | 00.00% | Unchanged |
| BML Capital Management, LLC |
| 2.83% | 3.42% | #2 | $5.0M | 645,600 | $5.3M | 645,600 | 00.00% | Unchanged |
| Vivo Capital, LLC |
| 0.21% | 0.2% | #4 | $2.3M | 292,743 | $2.4M | 292,743 | 00.00% | Unchanged |
| UBS Group AG |
| <0.01% | <0.01% | #10 | $1.4M | 177,423 | $52,554 | 6,378 | +171,045+2,681.80% | Add |
| VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #15 | $1.3M | 163,738 | $1.4M | 174,583 | -10,845-6.21% | Reduce |
| MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #9 | $1.0M | 134,575 | $1.1M | 132,946 | +1,629+1.23% | Add |
| Kalehua Capital Management LLC |
| 0.55% | 1.07% | #3 | $765,924 | 99,600 | $1.5M | 183,030 | -83,430-45.58% | Reduce |
| BlackRock, Inc. |
| <0.01% | <0.01% | #18 | $426,826 | 55,504 | $428,628 | 52,018 | +3,486+6.70% | Add |
| RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #8 | $386,807 | 50,300 | $486,984 | 59,100 | -8,800-14.89% | Reduce |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. |
| <0.01% | <0.01% | #7 | $385,000 | 50,000 | $412,000 | 50,000 | 00.00% | Unchanged |
| JACOBS LEVY EQUITY MANAGEMENT, INC |
| <0.01% | — | #6 | $331,062 | 43,051 | $0 | 0 | +43,051 | New Buy |
| GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #17 | $324,923 | 42,234 | $403,995 | 49,011 | -6,777-13.83% | Reduce |
| LPL Financial LLC |
| <0.01% | <0.01% | #11 | $246,653 | 32,075 | $264,199 | 32,063 | +12+0.04% | Add |
| CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #14 | $235,614 | 30,639 | $317,751 | 38,562 | -7,923-20.55% | Reduce |
| VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #12 | $175,124 | 22,773 | $186,430 | 22,625 | +148+0.65% | Add |
| STATE STREET CORP |
| <0.01% | <0.01% | #22 | $135,306 | 17,595 | $144,983 | 17,595 | 00.00% | Unchanged |
| Americana Partners, LLC |
| <0.01% | <0.01% | #5 | $124,393 | 16,176 | $133,290 | 16,176 | 00.00% | Unchanged |
| DIMENSIONAL FUND ADVISORS LP |
| <0.01% | <0.01% | #16 | $121,129 | 15,761 | $164,470 | 19,975 | -4,214-21.10% | Reduce |
| MORGAN STANLEY |
| <0.01% | <0.01% | #21 | $91,773 | 11,934 | $1.8M | 102,938 | -91,004-88.41% | Reduce |
| Vanguard Global Advisers, LLC |
| <0.01% | <0.01% | #20 | $11,304 | 1,470 | $12,113 | 1,470 | 00.00% | Unchanged |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO |
| <0.01% | — | #23 | $4,230 | 550 | $0 | 0 | +550 | New Buy |
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC |
| <0.01% | — | #13 | $961 | 125 | $0 | 0 | +125 | New Buy |
| CITIGROUP INC |
| <0.01% | — | #24 | $677 | 88 | $0 | 0 | +88 | New Buy |
| Tower Research Capital LLC (TRC) |
| <0.01% | — | #19 | $246 | 32 | $0 | 0 | +32 | New Buy |
| BARCLAYS PLC |
| <0.01% | <0.01% | #25 | $223 | 29 | $34,072 | 4,135 | -4,106-99.30% | Reduce |
| BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #26 | $54 | 7 | $58 | 7 | 00.00% | Unchanged |
