| BlackRock, Inc. |
| 0.01% | 0.01% | #197 | $995.2M | 28.7M | $546.8M | 26.3M | +2.4M+8.98% | Add |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| 0.06% | 0.06% | #102 | $782.6M | 22.6M | $520.1M | 25.1M | -2.5M-9.90% | Reduce |
| VANGUARD PORTFOLIO MANAGEMENT LLC |
| 0.02% | 0.01% | #186 | $366.1M | 10.6M | $211.4M | 10.2M | +375,501+3.69% | Add |
| CITADEL ADVISORS LLC |
| 0.04% | 0.04% | #126 | $348.1M | 10.0M | $244.8M | 11.8M | -1.8M-14.85% | Reduce |
| JANE STREET GROUP, LLC |
| 0.03% | 0.04% | #140 | $345.3M | 10.0M | $277.7M | 13.4M | -3.4M-25.53% | Reduce |
| VANGUARD CAPITAL MANAGEMENT LLC |
| 0.01% | <0.01% | #265 | $330.8M | 9.5M | $193.9M | 9.3M | +201,673+2.16% | Add |
| GOLDMAN SACHS GROUP INC |
| 0.03% | 0.01% | #157 | $291.8M | 8.4M | $53.5M | 2.6M | +5.8M+226.27% | Add |
| STATE STREET CORP |
| 0.01% | 0.01% | #242 | $282.4M | 8.1M | $154.9M | 7.5M | +685,676+9.19% | Add |
| MORGAN STANLEY |
| 0.01% | 0.02% | #201 | $248.0M | 7.2M | $412.7M | 7.3M | -123,598-1.70% | Reduce |
| Divisadero Street Capital Management, LP |
| 4.72% | 0.41% | #4 | $208.3M | 6.0M | $9.8M | 469,833 | +5.5M+1,179.07% | Add |
| GEODE CAPITAL MANAGEMENT, LLC |
| 0.01% | 0.01% | #220 | $197.0M | 5.7M | $107.9M | 5.2M | +483,053+9.29% | Add |
| D. E. Shaw & Co., Inc. |
| 0.09% | 0.03% | #87 | $179.4M | 5.2M | $51.7M | 2.5M | +2.7M+107.91% | Add |
| JPMORGAN CHASE & CO |
| 0.01% | 0.01% | #236 | $159.5M | 4.8M | $98.4M | 5.2M | -474,035-9.05% | Reduce |
| FMR LLC |
| 0.01% | <0.01% | #273 | $149.9M | 4.3M | $1.9M | 93,270 | +4.2M+4,535.24% | Add |
| MARSHALL WACE, LLP |
| 0.12% | 0.01% | #72 | $146.2M | 4.2M | $15.0M | 724,227 | +3.5M+482.38% | Add |
| UBS Group AG |
| 0.01% | 0.01% | #203 | $101.2M | 2.9M | $93.7M | 4.5M | -1.6M-35.32% | Reduce |
| NORTHERN TRUST CORP |
| 0.01% | 0.01% | #221 | $89.9M | 2.6M | $50.6M | 2.4M | +158,248+6.50% | Add |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| 0.01% | 0.01% | #212 | $85.1M | 2.5M | $49.0M | 2.4M | +95,073+4.03% | Add |
| STATE OF MICHIGAN RETIREMENT SYSTEM |
| 0.36% | 0.26% | #45 | $81.3M | 2.3M | $48.5M | 2.3M | +7,682+0.33% | Add |
| CITIGROUP INC |
| 0.03% | 0.01% | #151 | $80.4M | 2.3M | $13.8M | 662,928 | +1.7M+249.81% | Add |
| BANK OF AMERICA CORP /DE/ |
| 0.01% | 0.01% | #297 | $80.2M | 2.3M | $90.5M | 4.4M | -2.0M-46.94% | Reduce |
| Man Group plc |
| 0.1% | 0.06% | #80 | $61.2M | 1.8M | $33.5M | 1.6M | +153,192+9.50% | Add |
| PRINCIPAL FINANCIAL GROUP INC |
| 0.03% | 0.01% | #142 | $57.8M | 1.7M | $26.6M | 1.3M | +384,807+30.01% | Add |
| BANK OF MONTREAL /CAN/ |
| 0.02% | 0.02% | #174 | $55.9M | 1.6M | $51.7M | 2.5M | -879,732-35.30% | Reduce |
| Point72 Asset Management, L.P. |
| 0.06% | <0.01% | #106 | $52.9M | 1.5M | $3.7M | 180,500 | +1.3M+744.76% | Add |
| VANGUARD FIDUCIARY TRUST CO |
| 0.01% | 0.01% | #208 | $52.8M | 1.5M | $30.1M | 1.4M | +72,864+5.03% | Add |
| Walleye Trading LLC |
| 0.05% | 0.02% | #109 | $47.6M | 1.4M | $10.7M | 516,746 | +857,110+165.87% | Add |
| Bank of New York Mellon Corp |
| 0.01% | 0.01% | #252 | $46.2M | 1.3M | $27.8M | 1.3M | -7,300-0.54% | Reduce |
| PEAK6 LLC |
| 0.09% | 0.05% | #83 | $46.1M | 1.3M | $19.9M | 957,671 | +370,876+38.73% | Add |
| TUDOR INVESTMENT CORP ET AL |
| 0.06% | 0.07% | #95 | $46.0M | 1.3M | $35.1M | 1.7M | -364,704-21.56% | Reduce |
| CANTOR FITZGERALD, L. P. |
| 0.47% | 0.58% | #33 | $43.5M | 1.3M | $39.2M | 1.9M | -635,932-33.65% | Reduce |
| BARCLAYS PLC |
| 0.01% | 0.01% | #259 | $38.5M | 1.1M | $21.7M | 1.0M | +67,134+6.43% | Add |
| SCHRODER INVESTMENT MANAGEMENT GROUP |
| 0.03% | 0.01% | #147 | $37.7M | 1.1M | $13.8M | 732,766 | +397,015+54.18% | Add |
| FRANKLIN RESOURCES INC |
| 0.01% | <0.01% | #256 | $35.8M | 1.0M | $2.6M | 122,969 | +909,670+739.76% | Add |
| Clear Street Group Inc. |
| 0.09% | 0.12% | #86 | $34.3M | 989,913 | $30.0M | 1.4M | -455,486-31.51% | Reduce |
| Marex Group plc |
| 0.14% | 0.18% | #65 | $33.8M | 973,771 | $27.8M | 1.3M | -365,043-27.27% | Reduce |
| Jain Global LLC |
| 0.13% | <0.01% | #69 | $32.9M | 948,360 | $337,765 | 16,270 | +932,090+5,728.89% | Add |
| PRICE T ROWE ASSOCIATES INC /MD/ |
| <0.01% | <0.01% | #330 | $32.3M | 932,220 | $29.4M | 1.4M | -485,124-34.23% | Reduce |
| CAPITAL FUND MANAGEMENT S.A. |
| 0.14% | 0.05% | #67 | $31.3M | 902,412 | $11.2M | 541,343 | +361,069+66.70% | Add |
| HSBC HOLDINGS PLC |
| 0.01% | <0.01% | #202 | $31.2M | 911,708 | $1.7M | 84,159 | +827,549+983.32% | Add |
| NATIONAL BANK OF CANADA /FI/ |
| 0.03% | 0.03% | #158 | $29.0M | 836,955 | $29.5M | 1.4M | -582,920-41.05% | Reduce |
| IMC-Chicago, LLC |
| 0.01% | <0.01% | #272 | $27.4M | 789,513 | $10.6M | 508,575 | +280,938+55.24% | Add |
| Bienville Capital Management, LLC |
| 3.63% | — | #10 | $27.2M | 785,739 | $0 | 0 | +785,739 | New Buy |
| Nuveen, LLC |
| 0.01% | <0.01% | #274 | $27.2M | 783,594 | $14.1M | 678,120 | +105,474+15.55% | Add |
| BAILLIE GIFFORD & CO |
| 0.02% | — | #162 | $26.0M | 750,491 | $0 | 0 | +750,491 | New Buy |
| Foresite Capital Management V, LLC |
| 7.07% | 5.65% | #1 | $25.6M | 738,151 | $15.3M | 738,151 | 00.00% | Unchanged |
| Casdin Capital, LLC |
| 1.21% | 1.1% | #19 | $24.3M | 700,000 | $14.5M | 700,000 | 00.00% | Unchanged |
| Squarepoint Ops LLC |
| 0.03% | 0.01% | #149 | $23.9M | 689,708 | $5.8M | 280,048 | +409,660+146.28% | Add |
| MILLENNIUM MANAGEMENT LLC |
| 0.01% | 0.01% | #249 | $23.2M | 669,600 | $28.3M | 1.4M | -693,672-50.88% | Reduce |
| RHUMBLINE ADVISERS |
| 0.02% | 0.01% | #184 | $22.0M | 633,778 | $13.4M | 643,856 | -10,078-1.57% | Reduce |
