| Stonepine Capital Management, LLC |
| 0.17% | 0.25% | #2 | $113.5万 | 220.1万股 | $61.7万 | 83.1万股 | +137.0万股+164.82% | 加仓 |
| 木星资产管理Jupiter Topco LLC |
| <0.01% | — | #11 | $109.2万 | 210.0万股 | $0 | 0股 | +210.0万股 | 新买入 |
| Adage资本合伙人ADAGE CAPITAL PARTNERS GP, L.L.C. |
| <0.01% | <0.01% | #9 | $108.2万 | 210.0万股 | $155.8万 | 210.0万股 | 00.00% | 持仓不变 |
| Opaleye Management Inc. |
| 0.1% | — | #4 | $105.7万 | 205.0万股 | $0 | 0股 | +205.0万股 | 新买入 |
| 阿默普莱斯金融AMERIPRISE FINANCIAL INC |
| <0.01% | <0.01% | #12 | $96.1万 | 186.4万股 | $100.2万 | 135.1万股 | +51.4万股+38.02% | 加仓 |
| Cable Car 资本Cable Car Capital, LP |
| 0.29% | 0.3% | #1 | $89.5万 | 120.6万股 | $89.5万 | 120.6万股 | 00.00% | 持仓不变 |
| Squadron Capital Management LLC |
| 0.16% | 0.57% | #3 | $51.5万 | 100.0万股 | $155.8万 | 210.0万股 | -110.0万股-52.38% | 减仓 |
| AdvisorShares Investments LLC |
| 0.06% | 0.05% | #5 | $48.3万 | 93.8万股 | $25.0万 | 33.8万股 | +60.0万股+177.79% | 加仓 |
| Vivo Capital, LLC |
| 0.02% | 0.13% | #7 | $24.0万 | 46.5万股 | $155.8万 | 210.0万股 | -163.5万股-77.83% | 减仓 |
| Persistent Asset Partners Ltd |
| 0.05% | 0.08% | #6 | $15.0万 | 29.1万股 | $21.6万 | 29.1万股 | 00.00% | 持仓不变 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #18 | $9.7万 | 18.8万股 | $1.9万 | 2.6万股 | +16.2万股+619.38% | 加仓 |
| XTX资本XTX Topco Ltd |
| <0.01% | <0.01% | #10 | $6.6万 | 12.8万股 | $2.5万 | 3.4万股 | +9.4万股+277.98% | 加仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #22 | $6.5万 | 12.6万股 | $4.0万 | 5.4万股 | +7.2万股+134.65% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #20 | $4.3万 | 8.4万股 | $7.7万 | 10.4万股 | -2.0万股-19.36% | 减仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #15 | $3.4万 | 6.6万股 | $6.9万 | 9.3万股 | -2.8万股-29.76% | 减仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #16 | $3.3万 | 6.4万股 | $1.6万 | 2.1万股 | +4.3万股+204.77% | 加仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #19 | $2.3万 | 4.4万股 | $3.3万 | 4.4万股 | 00.00% | 持仓不变 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #21 | $1.6万 | 3.1万股 | $1.4万 | 1.9万股 | +1.2万股+62.12% | 加仓 |
| 跳跃金融Jump Financial, LLC |
| <0.01% | — | #13 | $1.5万 | 2.9万股 | $0 | 0股 | +2.9万股 | 新买入 |
| Tower Research Capital LLC (TRC) |
| <0.01% | <0.01% | #14 | $4,555 | 8,838股 | $1,375 | 1,854股 | +6,984股+376.70% | 加仓 |
| Hurley Capital, LLC |
| <0.01% | <0.01% | #8 | $3,608 | 7,000股 | $2,737 | 3,689股 | +3,311股+89.75% | 加仓 |
| SBI Securities Co., Ltd. |
| <0.01% | <0.01% | #17 | $542 | 1,051股 | $780 | 1,051股 | 00.00% | 持仓不变 |
| 巴克莱BARCLAYS PLC |
| <0.01% | — | #23 | $139 | 269股 | $0 | 0股 | +269股 | 新买入 |
| 摩根大通JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #24 | $79 | 150股 | $107 | 150股 | 00.00% | 持仓不变 |
