| 洞察顾问PERCEPTIVE ADVISORS LLC |
| 0.26% | 0.37% | #7 | $1,708.7万 | 185.9万股 | $1,911.4万 | 185.9万股 | 00.00% | 持仓不变 |
| ADAR1 Capital Management, LLC |
| 0.33% | 0.44% | #5 | $714.2万 | 77.7万股 | $747.9万 | 72.7万股 | +5.0万股+6.82% | 加仓 |
| ACORN CAPITAL ADVISORS, LLC |
| 1.59% | 1.85% | #2 | $583.1万 | 63.5万股 | $652.3万 | 63.5万股 | 00.00% | 持仓不变 |
| NEA Management Company, LLC |
| 0.27% | 0.27% | #6 | $426.8万 | 46.4万股 | $477.4万 | 46.4万股 | 00.00% | 持仓不变 |
| Commodore Capital LP |
| 0.25% | 0.28% | #8 | $426.8万 | 46.4万股 | $477.4万 | 46.4万股 | 00.00% | 持仓不变 |
| TCG Crossover 管理TCG Crossover Management, LLC |
| 0.1% | 0.13% | #10 | $426.8万 | 46.4万股 | $466.7万 | 46.4万股 | 00.00% | 持仓不变 |
| Spruce Street Capital LP |
| 0.71% | 0.92% | #4 | $361.8万 | 39.4万股 | $384.5万 | 39.4万股 | 00.00% | 持仓不变 |
| Kalehua Capital Management LLC |
| 2.59% | 2.86% | #1 | $361.8万 | 39.4万股 | $404.7万 | 39.4万股 | 00.00% | 持仓不变 |
| 黑石集团Blackstone Inc. |
| 0.01% | — | #12 | $298.3万 | 32.5万股 | $0 | 0股 | +32.5万股 | 新买入 |
| Adage资本合伙人ADAGE CAPITAL PARTNERS GP, L.L.C. |
| <0.01% | — | #13 | $275.7万 | 30.0万股 | $0 | 0股 | +30.0万股 | 新买入 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #23 | $252.9万 | 27.5万股 | $200.2万 | 19.5万股 | +8.0万股+41.32% | 加仓 |
| Seven Fleet Capital Management LP |
| 0.23% | 0.54% | #9 | $141.7万 | 15.4万股 | $169.3万 | 16.5万股 | -1.1万股-6.39% | 减仓 |
| 简化资产管理Simplify Asset Management Inc. |
| 0.02% | 0.02% | #11 | $137.2万 | 14.9万股 | $153.5万 | 14.9万股 | 00.00% | 持仓不变 |
| Propel Bio Management, LLC |
| 0.72% | 0.94% | #3 | $137.2万 | 14.9万股 | $149.6万 | 14.9万股 | 00.00% | 持仓不变 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #26 | $74.0万 | 8.0万股 | $82.6万 | 8.0万股 | +95股+0.12% | 加仓 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #30 | $72.8万 | 7.9万股 | $57.6万 | 5.6万股 | +2.3万股+41.27% | 加仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #16 | $71.2万 | 7.7万股 | $66.0万 | 6.4万股 | +1.3万股+20.56% | 加仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #22 | $39.3万 | 4.3万股 | $41.2万 | 4.0万股 | +2,775股+6.93% | 加仓 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #28 | $29.9万 | 3.3万股 | $33.5万 | 3.3万股 | -9股-0.03% | 减仓 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #19 | $29.8万 | 3.2万股 | $32.6万 | 3.2万股 | +772股+2.44% | 加仓 |
| 莱尔德·诺顿信托Laird Norton Wetherby Trust Company, LLC |
| <0.01% | <0.01% | #14 | $20.1万 | 2.2万股 | $22.4万 | 2.2万股 | 00.00% | 持仓不变 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #35 | $15.0万 | 1.6万股 | $16.8万 | 1.6万股 | 00.00% | 持仓不变 |
| 维度基金顾问DIMENSIONAL FUND ADVISORS LP |
| <0.01% | — | #27 | $13.5万 | 1.5万股 | $0 | 0股 | +1.5万股 | 新买入 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #29 | $13.2万 | 1.4万股 | $14.8万 | 1.4万股 | 00.00% | 持仓不变 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #21 | $12.2万 | 1.3万股 | $13.6万 | 1.3万股 | 00.00% | 持仓不变 |
| XTX资本XTX Topco Ltd |
| <0.01% | — | #15 | $10.8万 | 1.2万股 | $0 | 0股 | +1.2万股 | 新买入 |
| ACADIAN ASSET MANAGEMENT LLC |
| <0.01% | <0.01% | #18 | $9.4万 | 1.0万股 | $10.5万 | 1.0万股 | 00.00% | 持仓不变 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | — | #31 | $9.2万 | 1.0万股 | $0 | 0股 | +1.0万股 | 新买入 |
| OSAIC控股OSAIC HOLDINGS, INC. |
| <0.01% | <0.01% | #25 | $4.2万 | 4,580股 | $6.4万 | 6,180股 | -1,600股-25.89% | 减仓 |
| 摩根大通JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #38 | $1.8万 | 2,012股 | $111 | 12股 | +2,000股+16,666.67% | 加仓 |
| 先锋环球顾问Vanguard Global Advisers, LLC |
| <0.01% | <0.01% | #34 | $1.2万 | 1,325股 | $1.4万 | 1,325股 | 00.00% | 持仓不变 |
| 加拿大皇家银行ROYAL BANK OF CANADA |
| <0.01% | <0.01% | #37 | $8,000 | 844股 | $2.3万 | 2,225股 | -1,381股-62.07% | 减仓 |
| Tower Research Capital LLC (TRC) |
| <0.01% | — | #20 | $4,025 | 438股 | $0 | 0股 | +438股 | 新买入 |
| American Capital Advisory, LLC |
| <0.01% | <0.01% | #17 | $1,838 | 200股 | $2,056 | 200股 | 00.00% | 持仓不变 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #40 | $1,802 | 196股 | $1.3万 | 1,299股 | -1,103股-84.91% | 减仓 |
| ROTHSCHILD 投资ROTHSCHILD INVESTMENT LLC |
| <0.01% | <0.01% | #24 | $1,379 | 150股 | $1,542 | 150股 | 00.00% | 持仓不变 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #44 | $818 | 89股 | $2,112 | 510股 | -421股-82.55% | 减仓 |
| 美国合众银行US BANCORP \DE\ |
| <0.01% | <0.01% | #39 | $744 | 81股 | $833 | 81股 | 00.00% | 持仓不变 |
| 全球退休合伙人Global Retirement Partners, LLC |
| <0.01% | — | #33 | $477 | 52股 | $0 | 0股 | +52股 | 新买入 |
| 巴克莱BARCLAYS PLC |
| <0.01% | — | #43 | $386 | 42股 | $0 | 0股 | +42股 | 新买入 |
| 琼斯金融JONES FINANCIAL COMPANIES LLLP |
| <0.01% | <0.01% | #41 | $310 | 33股 | $296 | 33股 | 00.00% | 持仓不变 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #42 | $184 | 20股 | $236 | 23股 | -3股-13.04% | 减仓 |
| SBI Securities Co., Ltd. |
| <0.01% | <0.01% | #36 | $110 | 12股 | $123 | 12股 | 00.00% | 持仓不变 |
| Caitong International Asset Management Co., Ltd |
| <0.01% | <0.01% | #32 | $55 | 6股 | $62 | 6股 | 00.00% | 持仓不变 |
