| Velan Capital Investment Management LP |
| 4.1% | 2.71% | #1 | $672.8万 | 82.8万股 | $432.8万 | 82.8万股 | 00.00% | 持仓不变 |
| Rubric资本管理Rubric Capital Management LP |
| 0.05% | 0.04% | #5 | $544.3万 | 67.0万股 | $359.6万 | 68.8万股 | -1.8万股-2.62% | 减仓 |
| 洞察顾问PERCEPTIVE ADVISORS LLC |
| 0.07% | 0.06% | #4 | $457.9万 | 56.3万股 | $294.6万 | 56.3万股 | 00.00% | 持仓不变 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | — | #8 | $456.7万 | 56.2万股 | $0 | 0股 | +56.2万股 | 新买入 |
| Stonepine Capital Management, LLC |
| 0.49% | 0.06% | #2 | $319.1万 | 45.6万股 | $15.7万 | 3.0万股 | +42.6万股+1,421.46% | 加仓 |
| Boxer Capital Management, LLC |
| 0.13% | — | #3 | $166.7万 | 20.5万股 | $0 | 0股 | +20.5万股 | 新买入 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #18 | $66.5万 | 8.2万股 | $45.0万 | 8.6万股 | -4,127股-4.80% | 减仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #17 | $65.8万 | 8.1万股 | $40.3万 | 7.7万股 | +3,825股+4.96% | 加仓 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #16 | $58.9万 | 7.2万股 | $60.5万 | 11.6万股 | -4.3万股-37.38% | 减仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #14 | $31.5万 | 3.9万股 | $20.1万 | 3.8万股 | +272股+0.71% | 加仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #20 | $30.9万 | 3.8万股 | $19.9万 | 3.8万股 | 00.00% | 持仓不变 |
| XTX资本XTX Topco Ltd |
| <0.01% | — | #7 | $28.7万 | 3.5万股 | $0 | 0股 | +3.5万股 | 新买入 |
| HRT金融HRT FINANCIAL LP |
| <0.01% | — | #10 | $25.6万 | 3.2万股 | $0 | 0股 | +3.2万股 | 新买入 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #23 | $22.4万 | 2.7万股 | $14.5万 | 2.8万股 | -214股-0.77% | 减仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #19 | $12.2万 | 1.5万股 | $7.8万 | 1.5万股 | 00.00% | 持仓不变 |
| 丰业资本SCOTIA CAPITAL INC. |
| <0.01% | <0.01% | #11 | $11.7万 | 1.4万股 | $8.3万 | 1.6万股 | -1,450股-9.15% | 减仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| <0.01% | — | #13 | $11.4万 | 1.4万股 | $0 | 0股 | +1.4万股 | 新买入 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #21 | $5.5万 | 6,763股 | $1.2万 | 2,343股 | +4,420股+188.65% | 加仓 |
| SBI Securities Co., Ltd. |
| <0.01% | <0.01% | #9 | $2.8万 | 3,505股 | $1.8万 | 3,502股 | +3股+0.09% | 加仓 |
| 魁北克Desjardins联合会Federation des caisses Desjardins du Quebec |
| <0.01% | — | #15 | $2.1万 | 2,595股 | $0 | 0股 | +2,595股 | 新买入 |
| 加拿大皇家银行ROYAL BANK OF CANADA |
| <0.01% | <0.01% | #25 | $1.5万 | 1,851股 | $9,000 | 1,659股 | +192股+11.57% | 加仓 |
| MCGUIRE CAPITAL ADVISORS INC |
| 0.01% | 0.01% | #6 | $1.2万 | 1,500股 | $7,845 | 1,500股 | 00.00% | 持仓不变 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | — | #28 | $1.1万 | 1,400股 | $0 | 0股 | +1,400股 | 新买入 |
| Tower Research Capital LLC (TRC) |
| <0.01% | <0.01% | #12 | $1.0万 | 1,230股 | $2,652 | 507股 | +723股+142.60% | 加仓 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | — | #22 | $9,122 | 1,122股 | $0 | 0股 | +1,122股 | 新买入 |
| 摩根大通JPMORGAN CHASE & CO |
| <0.01% | — | #30 | $8,667 | 1,130股 | $0 | 0股 | +1,130股 | 新买入 |
| 先锋环球顾问Vanguard Global Advisers, LLC |
| <0.01% | <0.01% | #27 | $1,317 | 162股 | $847 | 162股 | 00.00% | 持仓不变 |
| 道明加拿大TD Waterhouse Canada Inc. |
| <0.01% | <0.01% | #24 | $1,098 | 142股 | $792 | 142股 | 00.00% | 持仓不变 |
| 美世全球顾问MERCER GLOBAL ADVISORS INC /ADV |
| <0.01% | — | #31 | $301 | 37股 | $0 | 0股 | +37股 | 新买入 |
| 琼斯金融JONES FINANCIAL COMPANIES LLLP |
| <0.01% | — | #32 | $66 | 8股 | $0 | 0股 | +8股 | 新买入 |
| 西北互惠财富管理NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO |
| <0.01% | — | #33 | $33 | 4股 | $0 | 0股 | +4股 | 新买入 |
| Banque Cantonale Vaudoise |
| <0.01% | — | #26 | $24 | 3股 | $0 | 0股 | +3股 | 新买入 |
| 丹麦银行DANSKE BANK A/S |
| <0.01% | <0.01% | #34 | $8 | 1股 | $5 | 1股 | 00.00% | 持仓不变 |
| LRI Investments, LLC |
| <0.01% | <0.01% | #29 | $8 | 1股 | $5 | 1股 | 00.00% | 持仓不变 |
