| GordonMD Global Investments LP |
| 11.95% | 4.19% | #1 | $3,017.5万 | 1,002.5万股 | $601.8万 | 412.2万股 | +590.3万股+143.21% | 加仓 |
| PFIZER INC |
| 11.43% | 3.86% | #2 | $1,948.1万 | 703.3万股 | $921.3万 | 703.3万股 | 00.00% | 持仓不变 |
| Laurion 资本管理Laurion Capital Management LP |
| 0.38% | 0.32% | #5 | $1,475.2万 | 490.1万股 | $729.6万 | 499.7万股 | -9.6万股-1.93% | 减仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #41 | $624.9万 | 207.6万股 | $296.9万 | 203.4万股 | +4.2万股+2.09% | 加仓 |
| Atle Fund Management AB |
| 0.78% | 0.52% | #3 | $290.9万 | 96.6万股 | $161.8万 | 19.7万股 | +76.9万股+390.50% | 加仓 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #56 | $261.2万 | 86.8万股 | $115.2万 | 78.9万股 | +7.9万股+10.03% | 加仓 |
| Palo Alto Investors LP |
| 0.38% | 0.23% | #4 | $260.1万 | 86.4万股 | $147.5万 | 101.1万股 | -14.6万股-14.47% | 减仓 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| <0.01% | <0.01% | #25 | $250.0万 | 83.1万股 | $51.7万 | 35.4万股 | +47.6万股+134.34% | 加仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #23 | $232.4万 | 77.2万股 | $129.7万 | 88.9万股 | -11.6万股-13.10% | 减仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #43 | $178.3万 | 59.2万股 | $87.4万 | 59.8万股 | -6,272股-1.05% | 减仓 |
| Woodline合伙人Woodline Partners LP |
| <0.01% | — | #17 | $157.7万 | 52.4万股 | $0 | 0股 | +52.4万股 | 新买入 |
| 683 Capital Management, LLC |
| 0.07% | 0.07% | #9 | $138.3万 | 45.9万股 | $130.9万 | 89.6万股 | -43.7万股-48.75% | 减仓 |
| Jacobs Levy股票管理JACOBS LEVY EQUITY MANAGEMENT, INC |
| <0.01% | <0.01% | #18 | $129.0万 | 42.9万股 | $67.3万 | 46.1万股 | -3.2万股-7.03% | 减仓 |
| DIADEMA PARTNERS LP |
| 0.14% | — | #6 | $116.8万 | 38.8万股 | $0 | 0股 | +38.8万股 | 新买入 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #45 | $109.5万 | 36.4万股 | $48.2万 | 33.0万股 | +3.4万股+10.25% | 加仓 |
| Longaeva 合伙人Longaeva Partners L.P. |
| 0.02% | 0.03% | #13 | $106.4万 | 35.4万股 | $73.5万 | 50.3万股 | -15.0万股-29.74% | 减仓 |
| Decheng Capital LLC |
| 0.13% | 0.07% | #7 | $98.4万 | 32.7万股 | $47.7万 | 32.7万股 | 00.00% | 持仓不变 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #36 | $91.2万 | 30.3万股 | $43.9万 | 30.1万股 | +2,089股+0.69% | 加仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #62 | $74.9万 | 24.9万股 | $36.3万 | 24.9万股 | 00.00% | 持仓不变 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #35 | $70.1万 | 23.3万股 | $58.1万 | 39.8万股 | -16.5万股-41.40% | 减仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #52 | $46.7万 | 15.5万股 | $37.1万 | 25.4万股 | -9.9万股-38.92% | 减仓 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| <0.01% | <0.01% | #50 | $40.3万 | 13.4万股 | $19.6万 | 13.4万股 | 00.00% | 持仓不变 |
| ACADIAN ASSET MANAGEMENT LLC |
| <0.01% | <0.01% | #31 | $38.2万 | 12.7万股 | $20.9万 | 14.4万股 | -1.7万股-12.11% | 减仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #54 | $37.3万 | 12.4万股 | $14.9万 | 10.2万股 | +2.2万股+21.59% | 加仓 |
| NewEdge财富NewEdge Wealth, LLC |
| <0.01% | <0.01% | #22 | $34.9万 | 11.6万股 | $16.9万 | 11.6万股 | 00.00% | 持仓不变 |
| XTX资本XTX Topco Ltd |
| <0.01% | 0.01% | #20 | $33.4万 | 11.1万股 | $29.2万 | 20.0万股 | -8.9万股-44.56% | 减仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #37 | $25.3万 | 8.4万股 | $10.7万 | 7.3万股 | +1.1万股+14.54% | 加仓 |
| 桥道资本管理BRIDGEWAY CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #21 | $24.5万 | 8.1万股 | $11.9万 | 8.1万股 | 00.00% | 持仓不变 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #65 | $24.2万 | 8.0万股 | $2.5万 | 1.7万股 | +6.4万股+378.75% | 加仓 |
| Stifel金融STIFEL FINANCIAL CORP |
| <0.01% | <0.01% | #38 | $21.2万 | 7.0万股 | $7.4万 | 5.1万股 | +2.0万股+39.38% | 加仓 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #66 | $19.6万 | 6.5万股 | $12.2万 | 8.4万股 | -1.8万股-22.04% | 减仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #63 | $18.7万 | 6.2万股 | $18.7万 | 12.8万股 | -6.6万股-51.68% | 减仓 |
| Cable Car 资本Cable Car Capital, LP |
| 0.06% | 0.03% | #10 | $18.5万 | 6.2万股 | $9.0万 | 6.2万股 | 00.00% | 持仓不变 |
| MYDA Advisors LLC |
| 0.02% | — | #14 | $15.1万 | 5.0万股 | $0 | 0股 | +5.0万股 | 新买入 |
| Qube研究科技Qube Research & Technologies Ltd |
| <0.01% | <0.01% | #40 | $15.0万 | 5.0万股 | $1.6万 | 1.1万股 | +3.9万股+342.42% | 加仓 |
| UNIVERSITY OF CHICAGO |
| 0.03% | 0.02% | #11 | $14.7万 | 4.9万股 | $7.1万 | 4.9万股 | 00.00% | 持仓不变 |
| 正交资本Quadrature Capital Ltd |
| <0.01% | — | #28 | $14.2万 | 4.7万股 | $0 | 0股 | +4.7万股 | 新买入 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #70 | $13.8万 | 4.6万股 | $6.9万 | 4.7万股 | -1,020股-2.17% | 减仓 |
| Verdad Advisers, LP |
| 0.13% | — | #8 | $13.5万 | 4.5万股 | $0 | 0股 | +4.5万股 | 新买入 |
| LPL金融LPL Financial LLC |
| <0.01% | <0.01% | #61 | $13.1万 | 4.4万股 | $4.9万 | 3.4万股 | +1.0万股+29.80% | 加仓 |
| Commonwealth股权服务COMMONWEALTH EQUITY SERVICES, LLC |
| <0.01% | <0.01% | #39 | $12.8万 | 4.2万股 | $5.1万 | 3.5万股 | +7,700股+22.16% | 加仓 |
| J. Derek Lewis & Associates Inc. |
| 0.02% | 0.01% | #12 | $12.6万 | 4.2万股 | $6.3万 | 4.3万股 | -1,000股-2.33% | 减仓 |
| 花旗集团CITIGROUP INC |
| <0.01% | <0.01% | #57 | $11.5万 | 3.8万股 | $2,540 | 1,740股 | +3.6万股+2,095.69% | 加仓 |
| Simplex交易SIMPLEX TRADING, LLC |
| <0.01% | <0.01% | #47 | $11.4万 | 3.8万股 | $369 | 253股 | +3.8万股+14,881.03% | 加仓 |
| Point72资产管理Point72 Asset Management, L.P. |
| <0.01% | <0.01% | #42 | $11.2万 | 3.7万股 | $4.7万 | 3.2万股 | +5,086股+15.89% | 加仓 |
| Walleye资本Walleye Capital LLC |
| <0.01% | — | #33 | $11.1万 | 3.7万股 | $0 | 0股 | +3.7万股 | 新买入 |
| 维度基金顾问DIMENSIONAL FUND ADVISORS LP |
| <0.01% | <0.01% | #64 | $10.9万 | 3.6万股 | $3.8万 | 2.6万股 | +1.0万股+39.61% | 加仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #73 | $10.1万 | 3.3万股 | $23.7万 | 10.7万股 | -7.3万股-68.62% | 减仓 |
| 麦肯齐金融MACKENZIE FINANCIAL CORP |
| <0.01% | — | #46 | $7.9万 | 2.6万股 | $0 | 0股 | +2.6万股 | 新买入 |
| Cetera投资顾问Cetera Investment Advisers |
| <0.01% | <0.01% | #48 | $7.5万 | 2.5万股 | $4.0万 | 2.7万股 | -2,260股-8.29% | 减仓 |
