| 贝莱德BlackRock, Inc. |
| 0.02% | 0.02% | #176 | $12.09亿 | 1,483.1万股 | $11.39亿 | 1,816.2万股 | -333.1万股-18.34% | 减仓 |
| Avoro资本顾问Avoro Capital Advisors LLC |
| 8.31% | 6.6% | #2 | $9.26亿 | 1,135.6万股 | $6.71亿 | 1,070.0万股 | +65.6万股+6.13% | 加仓 |
| 富达投资FMR LLC |
| 0.03% | 0.02% | #135 | $6.55亿 | 804.0万股 | $4.56亿 | 726.7万股 | +77.3万股+10.64% | 加仓 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| 0.02% | 0.02% | #151 | $5.18亿 | 635.1万股 | $4.48亿 | 714.6万股 | -79.5万股-11.12% | 减仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| 0.01% | 0.01% | #228 | $4.98亿 | 611.1万股 | $3.78亿 | 603.2万股 | +7.9万股+1.30% | 加仓 |
| 道富集团STATE STREET CORP |
| 0.01% | 0.01% | #197 | $4.64亿 | 569.5万股 | $4.07亿 | 649.6万股 | -80.1万股-12.34% | 减仓 |
| 挪威央行投资管理NORGES BANK |
| 0.03% | <0.01% | #128 | $3.18亿 | 389.7万股 | $2,296.5万 | 180.3万股 | +209.4万股+116.16% | 加仓 |
| 景顺Invesco Ltd. |
| 0.03% | 0.03% | #147 | $3.17亿 | 388.4万股 | $2.06亿 | 328.1万股 | +60.3万股+18.39% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| 0.02% | 0.02% | #185 | $2.99亿 | 353.1万股 | $2.75亿 | 427.9万股 | -74.8万股-17.49% | 减仓 |
| 弗雷德·阿尔杰管理FRED ALGER MANAGEMENT, LLC |
| 0.9% | 0.92% | #21 | $2.69亿 | 330.2万股 | $2.10亿 | 334.2万股 | -4.1万股-1.21% | 减仓 |
| 贝克兄弟顾问BAKER BROS. ADVISORS LP |
| 0.81% | 0.72% | #22 | $1.62亿 | 199.3万股 | $1.25亿 | 199.3万股 | 00.00% | 持仓不变 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| 0.01% | 0.01% | #209 | $1.54亿 | 188.9万股 | $1.15亿 | 183.6万股 | +5.2万股+2.84% | 加仓 |
| Siren, L.L.C. |
| 2.83% | 2.81% | #8 | $1.40亿 | 171.5万股 | $1.01亿 | 161.5万股 | +10.0万股+6.19% | 加仓 |
| Vestal Point 资本Vestal Point Capital, LP |
| 3% | 3.99% | #7 | $1.28亿 | 157.5万股 | $1.43亿 | 227.5万股 | -70.0万股-30.77% | 减仓 |
| Deerfield管理DEERFIELD MANAGEMENT COMPANY, L.P. |
| 1.18% | 1.16% | #17 | $1.13亿 | 138.9万股 | $9,864.6万 | 157.3万股 | -18.4万股-11.71% | 减仓 |
| 第一信托顾问FIRST TRUST ADVISORS LP |
| 0.06% | 0.01% | #87 | $1.10亿 | 135.3万股 | $935.2万 | 14.9万股 | +120.4万股+807.10% | 加仓 |
| Driehaus资本管理DRIEHAUS CAPITAL MANAGEMENT LLC |
| 0.64% | 0.55% | #25 | $1.10亿 | 135.1万股 | $7,463.4万 | 119.0万股 | +16.0万股+13.46% | 加仓 |
| 木星资产管理Jupiter Topco LLC |
| 0.04% | — | #114 | $9,962.3万 | 122.2万股 | $0 | 0股 | +122.2万股 | 新买入 |
| 北方信托NORTHERN TRUST CORP |
| 0.01% | 0.01% | #220 | $9,723.1万 | 119.3万股 | $1.04亿 | 165.6万股 | -46.3万股-27.96% | 减仓 |
| 维度基金顾问DIMENSIONAL FUND ADVISORS LP |
| 0.02% | 0.01% | #178 | $9,631.1万 | 118.2万股 | $3,815.0万 | 60.9万股 | +57.3万股+94.17% | 加仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| 0.01% | 0.01% | #253 | $9,373.7万 | 115.0万股 | $1.09亿 | 174.0万股 | -59.0万股-33.90% | 减仓 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| 0.01% | <0.01% | #285 | $9,290.6万 | 114.0万股 | $6,674.1万 | 106.4万股 | +7.5万股+7.08% | 加仓 |
| Hood River资本管理Hood River Capital Management LLC |
| 0.66% | 0.67% | #23 | $9,135.2万 | 112.1万股 | $6,624.5万 | 105.7万股 | +6.4万股+6.08% | 加仓 |
| Holocene顾问Holocene Advisors, LP |
| 0.2% | — | #44 | $9,016.4万 | 110.6万股 | $0 | 0股 | +110.6万股 | 新买入 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #310 | $8,842.5万 | 108.5万股 | $5,872.5万 | 170.3万股 | -61.8万股-36.29% | 减仓 |
| 瑞银资产管理(美洲)UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
| 0.01% | 0.02% | #193 | $7,861.5万 | 96.4万股 | $8,345.3万 | 133.1万股 | -36.7万股-27.54% | 减仓 |
| 费雪资产管理Fisher Asset Management, LLC |
| 0.02% | 0.02% | #152 | $7,806.1万 | 95.8万股 | $6,982.1万 | 111.4万股 | -15.6万股-14.00% | 减仓 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| 0.01% | 0.01% | #235 | $7,530.9万 | 92.4万股 | $7,474.4万 | 119.2万股 | -26.8万股-22.49% | 减仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| 0.02% | 0.02% | #182 | $7,309.3万 | 89.7万股 | $6,055.4万 | 96.6万股 | -6.9万股-7.15% | 减仓 |
| 瑞银集团UBS Group AG |
| 0.01% | 0.01% | #245 | $7,022.2万 | 86.2万股 | $8,378.4万 | 133.6万股 | -47.5万股-35.53% | 减仓 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| 0.01% | 0.01% | #218 | $7,006.1万 | 86.0万股 | $6,020.1万 | 96.0万股 | -10.1万股-10.48% | 减仓 |
| 普信集团PRICE T ROWE ASSOCIATES INC /MD/ |
| 0.01% | 0.01% | #274 | $6,955.7万 | 85.3万股 | $6,544.3万 | 104.4万股 | -19.0万股-18.24% | 减仓 |
| 峰会合伙人公共资产SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC |
| 1.19% | 1.16% | #16 | $6,767.3万 | 83.0万股 | $4,327.2万 | 69.0万股 | +14.0万股+20.30% | 加仓 |
| Western Financial Corp/CA |
| 19.58% | 20.13% | #1 | $6,685.8万 | 82.0万股 | $5,142.9万 | 82.0万股 | 00.00% | 持仓不变 |
| 摩根大通JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #357 | $5,177.0万 | 63.7万股 | $3,937.9万 | 68.3万股 | -4.6万股-6.69% | 减仓 |
| Connor Clark & Lunn投资管理Connor, Clark & Lunn Investment Management Ltd. |
| 0.1% | 0.12% | #68 | $5,099.0万 | 62.6万股 | $5,247.9万 | 83.7万股 | -21.1万股-25.26% | 减仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| 0.03% | <0.01% | #126 | $4,732.5万 | 58.1万股 | $286.5万 | 4.6万股 | +53.5万股+1,170.48% | 加仓 |
| 百达资产管理Pictet Asset Management Holding SA |
| 0.04% | 0.08% | #110 | $4,670.8万 | 57.3万股 | $7,961.2万 | 127.3万股 | -70.0万股-54.96% | 减仓 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| 0.02% | 0.02% | #159 | $4,553.5万 | 55.9万股 | $4,079.3万 | 65.1万股 | -9.2万股-14.13% | 减仓 |
| LORD, ABBETT & CO. LLC |
| 0.13% | 0.06% | #57 | $4,405.3万 | 54.0万股 | $1,961.4万 | 31.3万股 | +22.8万股+72.77% | 加仓 |
| 1832资产管理1832 Asset Management L.P. |
| 0.02% | — | #157 | $4,389.3万 | 53.9万股 | $0 | 0股 | +53.9万股 | 新买入 |
| 信安金融集团PRINCIPAL FINANCIAL GROUP INC |
| 0.02% | 0.02% | #164 | $4,195.0万 | 51.5万股 | $3,073.1万 | 49.0万股 | +2.5万股+5.01% | 加仓 |
| HRT金融HRT FINANCIAL LP |
| 0.07% | <0.01% | #79 | $4,064.5万 | 49.9万股 | $62.0万 | 9,900股 | +48.9万股+4,936.92% | 加仓 |
| Voya投资管理VOYA INVESTMENT MANAGEMENT LLC |
| 0.03% | 0.04% | #127 | $3,941.0万 | 48.3万股 | $4,113.9万 | 65.6万股 | -17.3万股-26.31% | 减仓 |
| Balyasny资产管理BALYASNY ASSET MANAGEMENT L.P. |
| 0.05% | 0.02% | #105 | $3,837.1万 | 47.1万股 | $1,294.2万 | 20.6万股 | +26.4万股+128.07% | 加仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| 0.05% | 0.1% | #100 | $3,822.2万 | 46.9万股 | $6,498.8万 | 103.6万股 | -56.8万股-54.76% | 减仓 |
| 富兰克林资源FRANKLIN RESOURCES INC |
| 0.01% | 0.01% | #262 | $3,766.8万 | 46.2万股 | $2,901.2万 | 46.3万股 | -574股-0.12% | 减仓 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #354 | $3,529.4万 | 43.3万股 | $1,787.4万 | 28.5万股 | +14.8万股+51.89% | 加仓 |
| D.E.肖D. E. Shaw & Co., Inc. |
| 0.02% | 0.04% | #179 | $3,517.6万 | 43.2万股 | $7,479.1万 | 119.3万股 | -76.1万股-63.82% | 减仓 |
| 纽文Nuveen, LLC |
| 0.01% | 0.01% | #255 | $3,389.9万 | 41.6万股 | $3,134.0万 | 50.0万股 | -8.4万股-16.80% | 减仓 |
