| Stonepine Capital Management, LLC |
| 0.31% | 0.14% | #2 | $204.2万 | 76.6万股 | $35.3万 | 5.3万股 | +71.2万股+1,332.00% | 加仓 |
| Dauntless Investment Group, LLC |
| 0.82% | 0.86% | #1 | $104.1万 | 21.5万股 | $129.8万 | 19.7万股 | +1.8万股+9.36% | 加仓 |
| Ikarian Capital, LLC |
| 0.11% | 0.11% | #3 | $102.4万 | 21.2万股 | $139.6万 | 21.2万股 | 00.00% | 持仓不变 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #13 | $54.4万 | 11.2万股 | $50.3万 | 7.6万股 | +3.6万股+47.31% | 加仓 |
| SummitTX 资本SummitTX Capital, L.P. |
| 0.01% | 0.02% | #7 | $48.5万 | 10.0万股 | $66.2万 | 10.0万股 | 00.00% | 持仓不变 |
| Woodline合伙人Woodline Partners LP |
| <0.01% | <0.01% | #10 | $37.0万 | 7.6万股 | $52.5万 | 8.0万股 | -3,136股-3.94% | 减仓 |
| 安本标准投资Aberdeen Group plc |
| <0.01% | <0.01% | #12 | $36.3万 | 7.5万股 | $49.5万 | 7.5万股 | 00.00% | 持仓不变 |
| Soleus 资本管理Soleus Capital Management, L.P. |
| 0.01% | 0.02% | #8 | $35.2万 | 7.3万股 | $48.0万 | 7.3万股 | 00.00% | 持仓不变 |
| AIGH Capital Management LLC |
| 0.02% | 0.05% | #6 | $33.9万 | 7.0万股 | $33.7万 | 5.1万股 | +1.9万股+37.25% | 加仓 |
| 布斯湾基金管理BOOTHBAY FUND MANAGEMENT, LLC |
| <0.01% | 0.01% | #9 | $29.0万 | 6.0万股 | $39.5万 | 6.0万股 | 00.00% | 持仓不变 |
| Velan Capital Investment Management LP |
| 0.1% | 0.35% | #4 | $15.7万 | 3.2万股 | $56.0万 | 8.5万股 | -5.2万股-61.85% | 减仓 |
| 巴克莱BARCLAYS PLC |
| <0.01% | <0.01% | #16 | $10.4万 | 2.1万股 | $8,580 | 1,300股 | +2.0万股+1,551.46% | 加仓 |
| Birchview Capital, LP |
| 0.04% | 0.08% | #5 | $9.7万 | 2.0万股 | $13.2万 | 2.0万股 | 00.00% | 持仓不变 |
| XTX资本XTX Topco Ltd |
| <0.01% | — | #11 | $7.3万 | 1.5万股 | $0 | 0股 | +1.5万股 | 新买入 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | — | #19 | $3.9万 | 8,000股 | $0 | 0股 | +8,000股 | 新买入 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #18 | $3.3万 | 6,772股 | $1.7万 | 2,512股 | +4,260股+169.59% | 加仓 |
| RhumbLine顾问RHUMBLINE ADVISERS |
| <0.01% | <0.01% | #17 | $1.1万 | 2,332股 | $1.0万 | 1,521股 | +811股+53.32% | 加仓 |
| GAMMA Investing LLC |
| <0.01% | <0.01% | #14 | $2,125 | 439股 | $1.1万 | 1,720股 | -1,281股-74.48% | 减仓 |
| SBI Securities Co., Ltd. |
| <0.01% | <0.01% | #15 | $1,718 | 355股 | $13 | 2股 | +353股+17,650.00% | 加仓 |
