| Decheng Capital LLC |
| 3.08% | 2.23% | #1 | $2,256.4万 | 391.7万股 | $1,476.8万 | 391.7万股 | 00.00% | 持仓不变 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #18 | $773.1万 | 134.2万股 | $488.5万 | 129.6万股 | +4.7万股+3.60% | 加仓 |
| Laurion 资本管理Laurion Capital Management LP |
| 0.15% | 0.17% | #2 | $595.8万 | 103.4万股 | $390.0万 | 103.4万股 | 00.00% | 持仓不变 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #37 | $324.2万 | 56.3万股 | $208.9万 | 55.4万股 | +8,776股+1.58% | 加仓 |
| AQR资本管理AQR CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #17 | $276.6万 | 48.0万股 | $50.7万 | 13.4万股 | +34.6万股+257.08% | 加仓 |
| EcoR1 Capital, LLC |
| 0.12% | — | #3 | $236.7万 | 41.1万股 | $0 | 0股 | +41.1万股 | 新买入 |
| Adage资本合伙人ADAGE CAPITAL PARTNERS GP, L.L.C. |
| <0.01% | <0.01% | #10 | $172.8万 | 30.0万股 | $113.1万 | 30.0万股 | 00.00% | 持仓不变 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #50 | $107.7万 | 18.7万股 | $298.8万 | 79.3万股 | -60.6万股-76.40% | 减仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #44 | $86.4万 | 15.0万股 | $116.7万 | 30.9万股 | -16.0万股-51.58% | 减仓 |
| 康托·菲茨杰拉德CANTOR FITZGERALD, L. P. |
| 0.01% | <0.01% | #6 | $67.2万 | 11.7万股 | $25.1万 | 6.7万股 | +5.0万股+74.83% | 加仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #21 | $62.4万 | 10.8万股 | $61.6万 | 16.3万股 | -5.5万股-33.66% | 减仓 |
| 雷蒙德詹姆斯金融RAYMOND JAMES FINANCIAL INC |
| <0.01% | <0.01% | #30 | $45.7万 | 7.9万股 | $4.1万 | 1.1万股 | +6.8万股+628.04% | 加仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #32 | $43.3万 | 7.5万股 | $31.4万 | 8.3万股 | -8,038股-9.66% | 减仓 |
| Woodline合伙人Woodline Partners LP |
| <0.01% | <0.01% | #13 | $41.7万 | 7.2万股 | $27.3万 | 7.2万股 | 00.00% | 持仓不变 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #27 | $40.3万 | 7.0万股 | $37.1万 | 9.8万股 | -2.8万股-28.87% | 减仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #53 | $34.1万 | 5.9万股 | $75.1万 | 19.9万股 | -14.0万股-70.26% | 减仓 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #47 | $26.3万 | 4.6万股 | $7.5万 | 2.0万股 | +2.6万股+128.32% | 加仓 |
| J. Goldman & Co LP |
| 0.01% | — | #7 | $23.3万 | 4.1万股 | $0 | 0股 | +4.1万股 | 新买入 |
| IEQ资本IEQ CAPITAL, LLC |
| <0.01% | <0.01% | #16 | $22.1万 | 3.8万股 | $6.2万 | 1.6万股 | +2.2万股+132.83% | 加仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #46 | $20.5万 | 3.6万股 | $59.5万 | 15.8万股 | -12.2万股-77.43% | 减仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #55 | $17.4万 | 3.0万股 | $91.0万 | 6.8万股 | -3.8万股-55.92% | 减仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #49 | $16.2万 | 2.8万股 | $33.4万 | 8.9万股 | -6.1万股-68.31% | 减仓 |
| 花旗集团CITIGROUP INC |
| <0.01% | <0.01% | #42 | $15.1万 | 2.6万股 | $17.4万 | 4.6万股 | -2.0万股-43.16% | 减仓 |
| Cresset资产管理Cresset Asset Management, LLC |
| <0.01% | <0.01% | #20 | $13.8万 | 2.4万股 | $16.3万 | 4.3万股 | -1.9万股-44.44% | 减仓 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | — | #52 | $13.8万 | 2.4万股 | $0 | 0股 | +2.4万股 | 新买入 |
| 桥道资本管理BRIDGEWAY CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #9 | $13.8万 | 2.4万股 | $10.2万 | 2.7万股 | -3,000股-11.11% | 减仓 |
| Point72资产管理Point72 Asset Management, L.P. |
| <0.01% | — | #26 | $13.2万 | 2.3万股 | $0 | 0股 | +2.3万股 | 新买入 |
| MarinerMariner, LLC |
| <0.01% | — | #29 | $12.5万 | 2.2万股 | $0 | 0股 | +2.2万股 | 新买入 |
| SMITH, MOORE & CO. |
| 0.01% | — | #5 | $11.5万 | 2.0万股 | $0 | 0股 | +2.0万股 | 新买入 |
| XTX资本XTX Topco Ltd |
| <0.01% | <0.01% | #11 | $11.5万 | 2.0万股 | $7.5万 | 2.0万股 | -27股-0.14% | 减仓 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| <0.01% | — | #33 | $11.0万 | 1.9万股 | $0 | 0股 | +1.9万股 | 新买入 |
| 富达投资FMR LLC |
| <0.01% | <0.01% | #63 | $10.9万 | 1.9万股 | $3.4万 | 8,958股 | +9,946股+111.03% | 加仓 |
| Simplex交易SIMPLEX TRADING, LLC |
| <0.01% | <0.01% | #40 | $9.2万 | 1.6万股 | $1.6万 | 4,243股 | +1.2万股+275.14% | 加仓 |
| 财富增值顾问WEALTH ENHANCEMENT ADVISORY SERVICES, LLC |
| <0.01% | — | #28 | $7.9万 | 1.0万股 | $0 | 0股 | +1.0万股 | 新买入 |
| PRELUDE CAPITAL MANAGEMENT, LLC |
| <0.01% | 0.01% | #8 | $7.2万 | 1.2万股 | $11.6万 | 3.1万股 | -1.8万股-59.44% | 减仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #60 | $7.1万 | 1.2万股 | $7.3万 | 1.9万股 | -7,163股-36.92% | 减仓 |
| 美世全球顾问MERCER GLOBAL ADVISORS INC /ADV |
| <0.01% | — | #35 | $6.6万 | 1.1万股 | $0 | 0股 | +1.1万股 | 新买入 |
| Cerity合伙人Cerity Partners LLC |
| <0.01% | — | #36 | $6.2万 | 1.1万股 | $0 | 0股 | +1.1万股 | 新买入 |
| Abel Hall, LLC |
| 0.01% | — | #4 | $5.8万 | 1.0万股 | $0 | 0股 | +1.0万股 | 新买入 |
| Arax顾问Arax Advisory Partners |
| <0.01% | <0.01% | #23 | $4.8万 | 8,374股 | $23 | 24股 | +8,350股+34,791.67% | 加仓 |
| 先锋环球顾问Vanguard Global Advisers, LLC |
| <0.01% | <0.01% | #51 | $3.4万 | 5,893股 | $2.2万 | 5,893股 | 00.00% | 持仓不变 |
| Steward合伙人投资顾问Steward Partners Investment Advisory, LLC |
| <0.01% | <0.01% | #31 | $2.4万 | 4,150股 | $1.6万 | 4,150股 | 00.00% | 持仓不变 |
| China Universal Asset Management Co., Ltd. |
| <0.01% | <0.01% | #15 | $2.0万 | 3,472股 | $1.5万 | 3,864股 | -392股-10.14% | 减仓 |
| Tower Research Capital LLC (TRC) |
| <0.01% | <0.01% | #22 | $1.4万 | 2,501股 | $2.1万 | 5,467股 | -2,966股-54.25% | 减仓 |
| 巴克莱BARCLAYS PLC |
| <0.01% | <0.01% | #66 | $1.3万 | 2,259股 | $1.4万 | 3,621股 | -1,362股-37.61% | 减仓 |
| Integrated Wealth ConceptsIntegrated Wealth Concepts LLC |
| <0.01% | — | #41 | $1.1万 | 1,943股 | $0 | 0股 | +1,943股 | 新买入 |
| 摩根大通JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #70 | $9,241 | 1,784股 | $2.4万 | 6,617股 | -4,833股-73.04% | 减仓 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #65 | $7,534 | 1,308股 | $1.2万 | 3,234股 | -1,926股-59.55% | 减仓 |
| 罗素投资集团Russell Investments Group, Ltd. |
| <0.01% | <0.01% | #61 | $7,137 | 1,239股 | $1,768 | 469股 | +770股+164.18% | 加仓 |
| Stone House Investment Management, LLC |
| <0.01% | <0.01% | #19 | $5,760 | 1,000股 | $3,770 | 1,000股 | 00.00% | 持仓不变 |
