| 木星资产管理Jupiter Topco LLC |
| 0.01% | — | #14 | $1,701.3万 | 129.3万股 | $0 | 0股 | +129.3万股 | 新买入 |
| 深轨资本Deep Track Capital, LP |
| 0.16% | 0.17% | #8 | $1,099.7万 | 83.6万股 | $1,061.3万 | 83.6万股 | 00.00% | 持仓不变 |
| 惠灵顿管理集团WELLINGTON MANAGEMENT GROUP LLP |
| <0.01% | <0.01% | #16 | $916.4万 | 69.6万股 | $884.4万 | 69.6万股 | 00.00% | 持仓不变 |
| Ally Bridge Group (NY) LLC |
| 7.22% | 4.25% | #1 | $816.3万 | 62.0万股 | $526.1万 | 41.4万股 | +20.6万股+49.76% | 加仓 |
| Trails Edge Capital Partners, LP |
| 1.16% | 1.62% | #4 | $733.1万 | 55.7万股 | $707.5万 | 55.7万股 | 00.00% | 持仓不变 |
| Woodline合伙人Woodline Partners LP |
| 0.02% | 0.02% | #12 | $581.6万 | 44.2万股 | $502.0万 | 39.5万股 | +4.7万股+11.79% | 加仓 |
| Yu Fan |
| 4.02% | 4.32% | #2 | $434.0万 | 33.0万股 | $418.8万 | 33.0万股 | 00.00% | 持仓不变 |
| SPHERA FUNDS MANAGEMENT LTD. |
| 0.56% | 0.66% | #5 | $428.5万 | 32.6万股 | $413.5万 | 32.6万股 | 00.00% | 持仓不变 |
| Squadron Capital Management LLC |
| 1.33% | 1.51% | #3 | $427.7万 | 32.5万股 | $412.7万 | 32.5万股 | 00.00% | 持仓不变 |
| Ikarian Capital, LLC |
| 0.29% | 0.06% | #6 | $269.8万 | 20.5万股 | $69.9万 | 5.5万股 | +15.0万股+272.73% | 加仓 |
| 阿默普莱斯金融AMERIPRISE FINANCIAL INC |
| <0.01% | — | #17 | $244.4万 | 18.6万股 | $0 | 0股 | +18.6万股 | 新买入 |
| Adage资本合伙人ADAGE CAPITAL PARTNERS GP, L.L.C. |
| <0.01% | <0.01% | #15 | $216.2万 | 16.4万股 | $176.9万 | 13.9万股 | +2.5万股+17.95% | 加仓 |
| 683 Capital Management, LLC |
| 0.06% | 0.06% | #9 | $125.0万 | 9.5万股 | $117.9万 | 9.3万股 | +2,150股+2.32% | 加仓 |
| ADAR1 Capital Management, LLC |
| 0.06% | 0.07% | #10 | $122.2万 | 9.3万股 | $121.1万 | 9.5万股 | -2,500股-2.62% | 减仓 |
| GREAT POINT PARTNERS LLC |
| 0.21% | 1.08% | #7 | $113.4万 | 8.6万股 | $471.7万 | 37.1万股 | -28.5万股-76.80% | 减仓 |
| 布斯湾基金管理BOOTHBAY FUND MANAGEMENT, LLC |
| 0.01% | <0.01% | #13 | $81.7万 | 6.2万股 | $20.4万 | 1.6万股 | +4.6万股+286.95% | 加仓 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #18 | $73.8万 | 5.6万股 | $99.0万 | 7.8万股 | -2.2万股-28.07% | 减仓 |
| 蒙特利尔银行BANK OF MONTREAL /CAN/ |
| <0.01% | — | #19 | $15.0万 | 1.1万股 | $0 | 0股 | +1.1万股 | 新买入 |
| Seven Fleet Capital Management LP |
| 0.02% | 0.04% | #11 | $13.9万 | 1.1万股 | $13.5万 | 1.1万股 | 00.00% | 持仓不变 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | — | #23 | $9.9万 | 7,559股 | $0 | 0股 | +7,559股 | 新买入 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #24 | $9,093 | 691股 | $1.7万 | 1,300股 | -609股-46.85% | 减仓 |
| OSAIC控股OSAIC HOLDINGS, INC. |
| <0.01% | <0.01% | #21 | $4,737 | 360股 | $4,572 | 360股 | 00.00% | 持仓不变 |
| 加拿大皇家银行ROYAL BANK OF CANADA |
| <0.01% | <0.01% | #25 | $3,000 | 218股 | $4,000 | 268股 | -50股-18.66% | 减仓 |
| Steward合伙人投资顾问Steward Partners Investment Advisory, LLC |
| <0.01% | <0.01% | #20 | $1,237 | 94股 | $1,270 | 100股 | -6股-6.00% | 减仓 |
| 魁北克Desjardins联合会Federation des caisses Desjardins du Quebec |
| <0.01% | <0.01% | #26 | $131 | 10股 | $127 | 10股 | 00.00% | 持仓不变 |
| 道明加拿大TD Waterhouse Canada Inc. |
| <0.01% | <0.01% | #27 | $66 | 5股 | $65 | 5股 | 00.00% | 持仓不变 |
| Caitong International Asset Management Co., Ltd |
| <0.01% | — | #22 | $39 | 3股 | $0 | 0股 | +3股 | 新买入 |
