| 木星资产管理Jupiter Topco LLC |
| 0.43% | — | #39 | $10.51亿 | 1,411.0万股 | $0 | 0股 | +1,411.0万股 | 新买入 |
| KKR集团Kohlberg Kravis Roberts & Co. L.P. |
| 17.3% | 18.42% | #2 | $9.88亿 | 1,326.1万股 | $9.85亿 | 1,326.1万股 | 00.00% | 持仓不变 |
| 法伦资本FARALLON CAPITAL MANAGEMENT, L.L.C. |
| 3.69% | 3.96% | #6 | $8.00亿 | 1,074.3万股 | $6.95亿 | 936.5万股 | +137.8万股+14.71% | 加仓 |
| 贝莱德BlackRock, Inc. |
| 0.01% | 0.02% | #213 | $7.66亿 | 1,028.7万股 | $10.55亿 | 1,420.8万股 | -392.1万股-27.59% | 减仓 |
| 维京全球投资VIKING GLOBAL INVESTORS LP |
| 2.11% | 2.46% | #14 | $7.41亿 | 994.9万股 | $8.79亿 | 1,184.2万股 | -189.3万股-15.99% | 减仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| 0.01% | 0.01% | #199 | $5.88亿 | 789.9万股 | $5.76亿 | 775.9万股 | +13.9万股+1.80% | 加仓 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| 0.03% | 0.03% | #157 | $5.70亿 | 765.7万股 | $6.00亿 | 808.1万股 | -42.4万股-5.25% | 减仓 |
| 简街集团JANE STREET GROUP, LLC |
| 0.04% | 0.05% | #141 | $4.55亿 | 611.3万股 | $3.66亿 | 493.5万股 | +117.8万股+23.87% | 加仓 |
| 瑞银集团UBS Group AG |
| 0.05% | 0.07% | #123 | $4.21亿 | 564.9万股 | $4.37亿 | 589.0万股 | -24.1万股-4.09% | 减仓 |
| 惠灵顿管理集团WELLINGTON MANAGEMENT GROUP LLP |
| 0.07% | 0.03% | #115 | $3.95亿 | 530.9万股 | $1.84亿 | 248.4万股 | +282.5万股+113.73% | 加仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| 0.26% | 0.19% | #53 | $3.53亿 | 474.5万股 | $2.32亿 | 312.1万股 | +162.5万股+52.06% | 加仓 |
| Aisling Capital Management LP |
| 72.48% | 79.35% | #1 | $3.42亿 | 459.0万股 | $3.78亿 | 509.0万股 | -50.0万股-9.82% | 减仓 |
| 道富集团STATE STREET CORP |
| 0.01% | 0.01% | #230 | $3.30亿 | 443.6万股 | $3.66亿 | 493.4万股 | -49.8万股-10.10% | 减仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| 0.04% | 0.04% | #143 | $3.22亿 | 432.7万股 | $2.52亿 | 339.0万股 | +93.7万股+27.63% | 加仓 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| 0.02% | 0.03% | #160 | $3.17亿 | 425.9万股 | $2.68亿 | 360.7万股 | +65.2万股+18.07% | 加仓 |
| 景顺Invesco Ltd. |
| 0.02% | 0.05% | #166 | $2.76亿 | 370.1万股 | $3.41亿 | 459.3万股 | -89.2万股-19.42% | 减仓 |
| D.E.肖D. E. Shaw & Co., Inc. |
| 0.13% | 0.11% | #80 | $2.73亿 | 366.4万股 | $1.89亿 | 254.5万股 | +111.8万股+43.94% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| 0.01% | 0.02% | #193 | $2.55亿 | 341.8万股 | $3.72亿 | 491.8万股 | -150.0万股-30.49% | 减仓 |
| 摩根大通JPMORGAN CHASE & CO |
| 0.01% | 0.01% | #235 | $1.73亿 | 239.8万股 | $9,101.8万 | 131.2万股 | +108.6万股+82.74% | 加仓 |
| Adage资本合伙人ADAGE CAPITAL PARTNERS GP, L.L.C. |
| 0.24% | 0.07% | #55 | $1.68亿 | 225.2万股 | $4,448.2万 | 59.9万股 | +165.3万股+275.96% | 加仓 |
| 富兰克林资源FRANKLIN RESOURCES INC |
| 0.03% | 0.04% | #147 | $1.61亿 | 216.0万股 | $1.81亿 | 243.9万股 | -27.9万股-11.43% | 减仓 |
| 极地资本控股Polar Capital Holdings Plc |
| 0.36% | 0.66% | #42 | $1.54亿 | 206.4万股 | $1.87亿 | 251.9万股 | -45.6万股-18.09% | 减仓 |
| 富达投资FMR LLC |
| 0.01% | 0.01% | #261 | $1.54亿 | 206.1万股 | $1.74亿 | 234.4万股 | -28.2万股-12.05% | 减仓 |
| 宏利人寿MANUFACTURERS LIFE INSURANCE COMPANY, THE |
| 0.11% | 0.13% | #88 | $1.46亿 | 195.6万股 | $1.47亿 | 197.7万股 | -2.1万股-1.08% | 减仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| 0.01% | 0.02% | #204 | $1.39亿 | 186.8万股 | $1.45亿 | 195.8万股 | -9.0万股-4.57% | 减仓 |
| SC US (TTGP)SC US (TTGP), LTD. |
| 0.43% | 1.49% | #38 | $1.39亿 | 186.0万股 | $1.38亿 | 186.0万股 | 00.00% | 持仓不变 |
| 普信集团PRICE T ROWE ASSOCIATES INC /MD/ |
| 0.01% | 0.03% | #197 | $1.29亿 | 172.6万股 | $2.82亿 | 380.2万股 | -207.5万股-54.59% | 减仓 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| 0.02% | 0.02% | #179 | $1.27亿 | 170.9万股 | $1.47亿 | 197.6万股 | -26.7万股-13.50% | 减仓 |
| 挪威央行投资管理NORGES BANK |
| 0.01% | 0.01% | #198 | $1.26亿 | 169.4万股 | $4,303.8万 | 124.5万股 | +44.9万股+36.05% | 加仓 |
| 摩根士丹利MORGAN STANLEY |
| 0.01% | <0.01% | #260 | $1.26亿 | 169.4万股 | $5,479.0万 | 105.5万股 | +63.9万股+60.56% | 加仓 |
| 阿默普莱斯金融AMERIPRISE FINANCIAL INC |
| 0.02% | 0.02% | #164 | $1.16亿 | 155.2万股 | $9,271.5万 | 124.9万股 | +30.3万股+24.28% | 加仓 |
| Frazier Life Sciences 管理Frazier Life Sciences Management, L.P. |
| 2.51% | 6.59% | #10 | $1.15亿 | 154.8万股 | $2.56亿 | 344.8万股 | -190.0万股-55.10% | 减仓 |
| Point72资产管理Point72 Asset Management, L.P. |
| 0.13% | <0.01% | #81 | $1.14亿 | 153.3万股 | $350.5万 | 4.7万股 | +148.6万股+3,147.42% | 加仓 |
| 联博ALLIANCEBERNSTEIN L.P. |
| 0.04% | 0.05% | #145 | $1.08亿 | 145.4万股 | $1.46亿 | 190.9万股 | -45.5万股-23.86% | 减仓 |
| 百达资产管理Pictet Asset Management Holding SA |
| 0.1% | 0.11% | #94 | $1.07亿 | 144.8万股 | $1.01亿 | 138.1万股 | +6.7万股+4.85% | 加仓 |
| Frontier资本管理FRONTIER CAPITAL MANAGEMENT CO LLC |
| 0.95% | 0.73% | #22 | $1.02亿 | 137.3万股 | $7,114.0万 | 95.8万股 | +41.5万股+43.33% | 加仓 |
| Laurion 资本管理Laurion Capital Management LP |
| 2.58% | 4.09% | #9 | $1.01亿 | 135.2万股 | $9,376.4万 | 126.3万股 | +9.0万股+7.09% | 加仓 |
| Hood River资本管理Hood River Capital Management LLC |
| 0.73% | 0.94% | #28 | $1.00亿 | 134.8万股 | $9,394.5万 | 126.5万股 | +8.2万股+6.52% | 加仓 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| 0.01% | 0.01% | #271 | $9,201.1万 | 123.5万股 | $9,548.0万 | 128.6万股 | -5.0万股-3.92% | 减仓 |
| Balyasny资产管理BALYASNY ASSET MANAGEMENT L.P. |
| 0.11% | 0.03% | #86 | $9,161.4万 | 123.0万股 | $2,599.8万 | 35.0万股 | +88.0万股+251.35% | 加仓 |
| SquarepointSquarepoint Ops LLC |
| 0.1% | 0.05% | #96 | $8,876.0万 | 119.2万股 | $4,131.3万 | 55.6万股 | +63.5万股+114.22% | 加仓 |
| Bellevue 集团Bellevue Group AG |
| 1.86% | 0.04% | #16 | $8,859.4万 | 119.0万股 | $188.4万 | 2.5万股 | +116.4万股+4,587.34% | 加仓 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| 0.04% | 0.05% | #137 | $8,605.7万 | 115.5万股 | $9,707.1万 | 130.7万股 | -15.2万股-11.61% | 减仓 |
| GW&K Investment Management, LLC |
| 0.65% | 0.63% | #31 | $8,380.0万 | 112.5万股 | $7,148.6万 | 96.3万股 | +16.2万股+16.88% | 加仓 |
| 花旗集团CITIGROUP INC |
| 0.03% | 0.03% | #153 | $8,342.5万 | 112.0万股 | $7,221.7万 | 97.2万股 | +14.8万股+15.18% | 加仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| 0.02% | 0.02% | #177 | $8,319.3万 | 111.7万股 | $8,726.6万 | 117.5万股 | -5.8万股-4.95% | 减仓 |
| HRT金融HRT FINANCIAL LP |
| 0.15% | 0.01% | #73 | $8,113.7万 | 108.9万股 | $533.6万 | 7.2万股 | +101.8万股+1,415.86% | 加仓 |
| 信安金融集团PRINCIPAL FINANCIAL GROUP INC |
| 0.04% | 0.05% | #142 | $7,629.9万 | 102.4万股 | $9,879.7万 | 133.0万股 | -30.6万股-23.00% | 减仓 |
| PRIMECAP管理PRIMECAP MANAGEMENT CO/CA/ |
| 0.04% | 0.03% | #133 | $7,567.0万 | 101.6万股 | $4,226.7万 | 56.9万股 | +44.7万股+78.50% | 加仓 |
| FIL(富达国际)FIL Ltd |
| 0.05% | <0.01% | #125 | $7,464.8万 | 100.2万股 | $6,535 | 88股 | +100.2万股+1,138,831.82% | 加仓 |
