| DAFNA Capital Management LLC |
| 4.49% | 5.73% | #1 | $2,353.1万 | 1,368.1万股 | $2,517.2万 | 1,368.1万股 | 00.00% | 持仓不变 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #48 | $756.3万 | 439.7万股 | $727.9万 | 395.6万股 | +44.1万股+11.14% | 加仓 |
| Lagoda Investment Management, L.P. |
| 3.9% | 4.94% | #2 | $709.1万 | 412.3万股 | $800.5万 | 435.0万股 | -22.8万股-5.24% | 减仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #47 | $523.7万 | 304.5万股 | $551.6万 | 299.8万股 | +4.7万股+1.56% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #41 | $326.1万 | 189.5万股 | $308.4万 | 167.5万股 | +22.0万股+13.12% | 加仓 |
| ESSEX INVESTMENT MANAGEMENT CO LLC |
| 0.34% | 0.46% | #6 | $261.8万 | 152.2万股 | $292.6万 | 159.0万股 | -6.8万股-4.28% | 减仓 |
| Archon Capital Management LLC |
| 0.86% | 1.27% | #4 | $210.9万 | 122.6万股 | $225.6万 | 122.6万股 | 00.00% | 持仓不变 |
| Warberg Asset Management LLC |
| 0.35% | 0.34% | #5 | $190.7万 | 110.9万股 | $201.3万 | 109.4万股 | +1.5万股+1.35% | 加仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #58 | $157.7万 | 91.7万股 | $176.2万 | 95.8万股 | -4.1万股-4.28% | 减仓 |
| AlphaCentric Advisors LLC |
| 0.87% | 1.1% | #3 | $103.2万 | 60.0万股 | $110.4万 | 60.0万股 | 00.00% | 持仓不变 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #39 | $101.3万 | 58.9万股 | $97.5万 | 53.0万股 | +5.9万股+11.18% | 加仓 |
| 瑞士宝盛银行Bank Julius Baer & Co. Ltd, Zurich |
| <0.01% | <0.01% | #26 | $93.0万 | 54.1万股 | $99.5万 | 54.1万股 | +1股+0.00% | 加仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #49 | $91.1万 | 53.0万股 | $91.4万 | 49.7万股 | +3.3万股+6.59% | 加仓 |
| Legato Capital Management LLC |
| 0.07% | — | #7 | $88.2万 | 51.3万股 | $0 | 0股 | +51.3万股 | 新买入 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #63 | $79.7万 | 46.4万股 | $67.8万 | 36.9万股 | +9.5万股+25.76% | 加仓 |
| 红杉金融顾问Sequoia Financial Advisors, LLC |
| <0.01% | <0.01% | #25 | $65.6万 | 38.1万股 | $70.0万 | 38.1万股 | +703股+0.18% | 加仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #68 | $57.1万 | 33.2万股 | $36.6万 | 11.8万股 | +21.4万股+182.10% | 加仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #56 | $43.2万 | 25.1万股 | $43.7万 | 23.7万股 | +1.4万股+5.92% | 加仓 |
| PRESCOTT GROUP CAPITAL MANAGEMENT, L.L.C. |
| 0.04% | 0.04% | #9 | $40.8万 | 23.7万股 | $43.7万 | 23.7万股 | 00.00% | 持仓不变 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #64 | $40.4万 | 23.5万股 | $49.5万 | 26.9万股 | -3.4万股-12.67% | 减仓 |
| SEI投资SEI INVESTMENTS CO |
| <0.01% | <0.01% | #32 | $40.4万 | 23.5万股 | $95.5万 | 51.9万股 | -28.4万股-54.79% | 减仓 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| <0.01% | <0.01% | #54 | $36.4万 | 21.2万股 | $36.1万 | 19.6万股 | +1.6万股+7.99% | 加仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #60 | $36.1万 | 21.0万股 | $4.3万 | 2.4万股 | +18.6万股+792.29% | 加仓 |
| Independent Advisor Alliance |
| 0.01% | <0.01% | #18 | $35.9万 | 20.8万股 | $37.0万 | 20.1万股 | +7,500股+3.73% | 加仓 |
| AQR资本管理AQR CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #46 | $33.8万 | 19.7万股 | $12.0万 | 6.5万股 | +13.1万股+201.24% | 加仓 |
| 桥道资本管理BRIDGEWAY CAPITAL MANAGEMENT, LLC |
| 0.01% | 0.01% | #20 | $29.9万 | 17.4万股 | $40.8万 | 22.1万股 | -4.8万股-21.54% | 减仓 |
| 加拿大皇家银行ROYAL BANK OF CANADA |
| <0.01% | <0.01% | #59 | $28.4万 | 16.5万股 | $29.7万 | 16.1万股 | +4,180股+2.59% | 加仓 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #66 | $24.8万 | 14.4万股 | $31.8万 | 17.3万股 | -2.9万股-16.55% | 减仓 |
| 普信集团PRICE T ROWE ASSOCIATES INC /MD/ |
| <0.01% | <0.01% | #72 | $24.2万 | 14.1万股 | $21.6万 | 11.7万股 | +2.4万股+20.34% | 加仓 |
| RhumbLine顾问RHUMBLINE ADVISERS |
| <0.01% | <0.01% | #42 | $22.4万 | 13.0万股 | $24.4万 | 13.2万股 | -2,311股-1.75% | 减仓 |
| GMT CAPITAL CORP |
| 0.01% | 0.01% | #15 | $21.8万 | 12.7万股 | $23.3万 | 12.7万股 | 00.00% | 持仓不变 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #86 | $20.2万 | 11.7万股 | $9.2万 | 5.0万股 | +6.8万股+135.83% | 加仓 |
| Kovack Advisors, Inc. |
| 0.01% | 0.01% | #17 | $17.9万 | 10.1万股 | $20.1万 | 10.9万股 | -7,791股-7.15% | 减仓 |
| Envestnet资产管理ENVESTNET ASSET MANAGEMENT INC |
| <0.01% | <0.01% | #61 | $15.8万 | 9.2万股 | $25.0万 | 13.6万股 | -4.4万股-32.55% | 减仓 |
| Leonteq Securities AG |
| <0.01% | 0.01% | #23 | $12.9万 | 7.5万股 | $13.8万 | 7.5万股 | 00.00% | 持仓不变 |
| 纽文Nuveen, LLC |
| <0.01% | <0.01% | #67 | $12.7万 | 7.4万股 | $13.6万 | 7.4万股 | 00.00% | 持仓不变 |
| TCFG Investment Advisors, LLC |
| 0.04% | 0.04% | #8 | $11.9万 | 6.9万股 | $11.8万 | 6.4万股 | +5,000股+7.81% | 加仓 |
| WEALTH EFFECTS LLC |
| 0.03% | 0.04% | #10 | $11.8万 | 6.9万股 | $12.6万 | 6.9万股 | 00.00% | 持仓不变 |
| 汇丰控股HSBC HOLDINGS PLC |
| <0.01% | <0.01% | #57 | $11.7万 | 6.9万股 | $12.5万 | 6.9万股 | 00.00% | 持仓不变 |
| DEUTSCHE 银行 AG\DEUTSCHE BANK AG\ |
| <0.01% | <0.01% | #65 | $11.6万 | 6.8万股 | $1,869 | 1,016股 | +6.7万股+6,547.34% | 加仓 |
| 巴克莱BARCLAYS PLC |
| <0.01% | <0.01% | #74 | $11.5万 | 6.7万股 | $12.5万 | 6.8万股 | -886股-1.31% | 减仓 |
| 富国银行WELLS FARGO & COMPANY/MN |
| <0.01% | <0.01% | #77 | $10.7万 | 6.2万股 | $4.2万 | 2.3万股 | +4.0万股+174.85% | 加仓 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #90 | $8.7万 | 5.1万股 | $19.9万 | 10.8万股 | -5.8万股-53.27% | 减仓 |
| Cherry Creek Investment Advisors, Inc. |
| 0.03% | 0.03% | #11 | $7.3万 | 4.3万股 | $6.7万 | 3.6万股 | +6,386股+17.63% | 加仓 |
| Wellington Shields & Co., LLC |
| 0.02% | 0.02% | #13 | $6.9万 | 4.0万股 | $7.4万 | 4.0万股 | 00.00% | 持仓不变 |
| 景顺Invesco Ltd. |
| <0.01% | <0.01% | #95 | $6.6万 | 3.9万股 | $4.9万 | 2.6万股 | +1.2万股+46.00% | 加仓 |
| Verition基金管理Verition Fund Management LLC |
| <0.01% | <0.01% | #52 | $6.0万 | 3.5万股 | $4.0万 | 2.2万股 | +1.3万股+59.09% | 加仓 |
| 先锋环球顾问Vanguard Global Advisers, LLC |
| <0.01% | <0.01% | #71 | $5.9万 | 3.4万股 | $6.3万 | 3.4万股 | 00.00% | 持仓不变 |
| 花旗集团CITIGROUP INC |
| <0.01% | <0.01% | #76 | $5.5万 | 3.2万股 | $6,143 | 3,339股 | +2.9万股+858.31% | 加仓 |
| 未来资产环球ETFMIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
| <0.01% | <0.01% | #53 | $5.4万 | 3.1万股 | $5.3万 | 2.9万股 | +2,492股+8.62% | 加仓 |
