| Knoll Capital Management, LLC |
| 6.69% | 4.9% | #1 | $1,166.3万 | 547.6万股 | $925.4万 | 547.6万股 | 00.00% | 持仓不变 |
| AQR资本管理AQR CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #20 | $799.1万 | 375.2万股 | $478.2万 | 283.0万股 | +92.2万股+32.57% | 加仓 |
| KINGDON CAPITAL MANAGEMENT, L.L.C. |
| 0.58% | 0.4% | #2 | $564.9万 | 265.2万股 | $363.7万 | 215.2万股 | +50.0万股+23.23% | 加仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #69 | $503.1万 | 236.2万股 | $399.5万 | 236.4万股 | -1,946股-0.08% | 减仓 |
| D.E.肖D. E. Shaw & Co., Inc. |
| <0.01% | <0.01% | #29 | $413.3万 | 194.0万股 | $237.3万 | 140.4万股 | +53.6万股+38.20% | 加仓 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| <0.01% | <0.01% | #25 | $321.0万 | 150.7万股 | $21.9万 | 13.0万股 | +137.7万股+1,061.95% | 加仓 |
| 683 Capital Management, LLC |
| 0.15% | 0.13% | #4 | $308.9万 | 145.0万股 | $253.5万 | 150.0万股 | -5.0万股-3.33% | 减仓 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #49 | $297.4万 | 139.6万股 | $192.8万 | 114.1万股 | +25.5万股+22.39% | 加仓 |
| ARDSLEY ADVISORY PARTNERS LP |
| 0.28% | 0.27% | #3 | $271.6万 | 127.5万股 | $211.3万 | 125.0万股 | +2.5万股+2.00% | 加仓 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #85 | $267.8万 | 125.7万股 | $636.1万 | 376.4万股 | -250.7万股-66.60% | 减仓 |
| Qube研究科技Qube Research & Technologies Ltd |
| <0.01% | <0.01% | #26 | $240.4万 | 112.9万股 | $14.7万 | 8.7万股 | +104.2万股+1,196.31% | 加仓 |
| ACADIAN ASSET MANAGEMENT LLC |
| <0.01% | <0.01% | #22 | $226.6万 | 106.4万股 | $144.6万 | 85.8万股 | +20.6万股+23.94% | 加仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #24 | $187.9万 | 88.2万股 | $145.9万 | 86.3万股 | +1.9万股+2.18% | 加仓 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #74 | $169.3万 | 79.5万股 | $136.5万 | 80.8万股 | -1.3万股-1.60% | 减仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #63 | $154.5万 | 72.5万股 | $91.8万 | 54.3万股 | +18.2万股+33.56% | 加仓 |
| Jacobs Levy股票管理JACOBS LEVY EQUITY MANAGEMENT, INC |
| <0.01% | 0.01% | #14 | $137.8万 | 64.7万股 | $134.7万 | 79.7万股 | -15.0万股-18.82% | 减仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #77 | $129.6万 | 60.8万股 | $565.5万 | 108.3万股 | -47.5万股-43.85% | 减仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #78 | $127.0万 | 59.6万股 | $211.6万 | 125.2万股 | -65.6万股-52.38% | 减仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #64 | $115.6万 | 54.3万股 | $70.4万 | 41.7万股 | +12.6万股+30.20% | 加仓 |
| 维度基金顾问DIMENSIONAL FUND ADVISORS LP |
| <0.01% | <0.01% | #52 | $112.7万 | 52.9万股 | $105.5万 | 62.4万股 | -9.5万股-15.23% | 减仓 |
| GSA CAPITAL PARTNERS LLP |
| 0.06% | 0.03% | #6 | $100.7万 | 47.3万股 | $41.8万 | 24.7万股 | +22.5万股+91.17% | 加仓 |
| 箭街资本ARROWSTREET CAPITAL, LIMITED PARTNERSHIP |
| <0.01% | — | #43 | $89.7万 | 42.1万股 | $0 | 0股 | +42.1万股 | 新买入 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #48 | $76.8万 | 36.0万股 | $168.2万 | 99.5万股 | -63.5万股-63.79% | 减仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #73 | $64.3万 | 30.2万股 | $90.8万 | 53.8万股 | -23.6万股-43.83% | 减仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #62 | $63.5万 | 29.8万股 | $57.2万 | 33.9万股 | -4.0万股-11.92% | 减仓 |
| XTX资本XTX Topco Ltd |
| 0.01% | <0.01% | #10 | $54.3万 | 25.5万股 | $12.7万 | 7.5万股 | +18.0万股+238.95% | 加仓 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #84 | $51.6万 | 24.2万股 | $105.2万 | 62.2万股 | -38.0万股-61.10% | 减仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #97 | $49.8万 | 23.4万股 | $190.1万 | 112.5万股 | -89.1万股-79.21% | 减仓 |
| WOODSTOCK CORP |
| 0.04% | 0.04% | #8 | $45.1万 | 26.7万股 | $45.1万 | 26.7万股 | 00.00% | 持仓不变 |
| IEQ资本IEQ CAPITAL, LLC |
| <0.01% | <0.01% | #28 | $44.0万 | 20.7万股 | $45.0万 | 26.7万股 | -6.0万股-22.48% | 减仓 |
| 康托·菲茨杰拉德CANTOR FITZGERALD, L. P. |
| <0.01% | — | #15 | $42.6万 | 20.0万股 | $0 | 0股 | +20.0万股 | 新买入 |
| Caption管理Caption Management, LLC |
| <0.01% | <0.01% | #31 | $35.1万 | 16.5万股 | $27.9万 | 16.5万股 | 00.00% | 持仓不变 |
| 富国银行WELLS FARGO & COMPANY/MN |
| <0.01% | <0.01% | #79 | $34.6万 | 16.2万股 | $32.1万 | 19.0万股 | -2.7万股-14.44% | 减仓 |
| 景顺Invesco Ltd. |
| <0.01% | <0.01% | #92 | $34.0万 | 16.0万股 | $28.7万 | 17.0万股 | -1.0万股-5.99% | 减仓 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #58 | $33.5万 | 15.7万股 | $5.0万 | 3.0万股 | +12.7万股+427.41% | 加仓 |
| Palo Alto Investors LP |
| 0.05% | 0.04% | #7 | $33.2万 | 15.6万股 | $26.3万 | 15.6万股 | 00.00% | 持仓不变 |
| Point72资产管理Point72 Asset Management, L.P. |
| <0.01% | — | #44 | $32.9万 | 15.4万股 | $0 | 0股 | +15.4万股 | 新买入 |
| Connor Clark & Lunn投资管理Connor, Clark & Lunn Investment Management Ltd. |
| <0.01% | — | #38 | $32.9万 | 15.4万股 | $0 | 0股 | +15.4万股 | 新买入 |
| 英仕曼集团Man Group plc |
| <0.01% | — | #40 | $32.5万 | 15.3万股 | $0 | 0股 | +15.3万股 | 新买入 |
| Jain GlobalJain Global LLC |
| <0.01% | — | #33 | $28.0万 | 13.2万股 | $0 | 0股 | +13.2万股 | 新买入 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #54 | $27.2万 | 12.8万股 | $37.8万 | 22.4万股 | -9.6万股-42.81% | 减仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #91 | $23.2万 | 10.9万股 | $63.3万 | 37.5万股 | -26.6万股-70.95% | 减仓 |
| 摩根大通JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #98 | $22.5万 | 11.0万股 | $3.9万 | 2.3万股 | +8.6万股+373.18% | 加仓 |
| 肯尼迪资本管理KENNEDY CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #16 | $20.8万 | 9.8万股 | $16.2万 | 9.6万股 | +1,864股+1.94% | 加仓 |
| 加拿大养老金计划投资委员会(CPPIB)CANADA PENSION PLAN INVESTMENT BOARD |
| <0.01% | <0.01% | #67 | $20.1万 | 9.4万股 | $8.0万 | 4.7万股 | +4.7万股+98.95% | 加仓 |
| SquarepointSquarepoint Ops LLC |
| <0.01% | — | #50 | $20.0万 | 9.4万股 | $0 | 0股 | +9.4万股 | 新买入 |
| Group One交易GROUP ONE TRADING LLC |
| <0.01% | <0.01% | #47 | $19.4万 | 9.1万股 | $19.7万 | 11.7万股 | -2.6万股-21.85% | 减仓 |
| 罗素投资集团Russell Investments Group, Ltd. |
| <0.01% | <0.01% | #61 | $19.2万 | 9.0万股 | $14.2万 | 8.4万股 | +6,053股+7.18% | 加仓 |
| MarinerMariner, LLC |
| <0.01% | <0.01% | #53 | $19.2万 | 9.0万股 | $15.5万 | 9.2万股 | -1,531股-1.67% | 减仓 |
| 加拿大皇家银行ROYAL BANK OF CANADA |
| <0.01% | <0.01% | #94 | $17.0万 | 8.0万股 | $2,000 | 1,368股 | +7.8万股+5,732.09% | 加仓 |
