| Cormorant Asset Management, LP |
| 1.12% | 1.11% | #2 | $2,199.6万 | 234.5万股 | $2,201.9万 | 234.5万股 | 00.00% | 持仓不变 |
| 奥比梅德顾问ORBIMED ADVISORS LLC |
| 0.31% | 0.32% | #9 | $1,629.6万 | 173.7万股 | $1,631.3万 | 173.7万股 | 00.00% | 持仓不变 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #54 | $1,248.6万 | 133.1万股 | $255.1万 | 27.2万股 | +105.9万股+390.04% | 加仓 |
| 安本标准投资Aberdeen Group plc |
| 0.02% | 0.02% | #18 | $1,239.8万 | 132.2万股 | $1,241.1万 | 132.2万股 | 00.00% | 持仓不变 |
| DIADEMA PARTNERS LP |
| 1.08% | 0.89% | #3 | $877.1万 | 93.5万股 | $521.4万 | 55.5万股 | +38.0万股+68.40% | 加仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #55 | $713.8万 | 76.1万股 | $689.3万 | 73.4万股 | +2.7万股+3.66% | 加仓 |
| Jones Hill Capital LP |
| 1.3% | — | #1 | $613.1万 | 65.4万股 | $0 | 0股 | +65.4万股 | 新买入 |
| Prosight Management, LP |
| 1.05% | 1.07% | #5 | $609.7万 | 65.0万股 | $654.6万 | 69.7万股 | -4.7万股-6.76% | 减仓 |
| Caption管理Caption Management, LLC |
| 0.03% | <0.01% | #16 | $562.9万 | 60.0万股 | $6.1万 | 6,470股 | +59.4万股+9,175.92% | 加仓 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #42 | $551.3万 | 58.8万股 | $392.8万 | 41.8万股 | +16.9万股+40.49% | 加仓 |
| ADAR1 Capital Management, LLC |
| 0.21% | 0.2% | #11 | $451.9万 | 48.2万股 | $344.4万 | 36.7万股 | +11.5万股+31.36% | 加仓 |
| Stonepine Capital Management, LLC |
| 0.61% | 1.44% | #6 | $398.7万 | 42.5万股 | $360.1万 | 38.3万股 | +4.2万股+10.83% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #52 | $397.2万 | 42.3万股 | $175.7万 | 18.7万股 | +23.6万股+126.37% | 加仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #66 | $238.9万 | 25.5万股 | $64.7万 | 6.9万股 | +18.6万股+269.78% | 加仓 |
| Group One交易GROUP ONE TRADING LLC |
| <0.01% | <0.01% | #27 | $225.2万 | 24.0万股 | $6.8万 | 7,198股 | +23.3万股+3,235.65% | 加仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #49 | $210.8万 | 22.5万股 | $757.4万 | 80.7万股 | -58.2万股-72.13% | 减仓 |
| 维度基金顾问DIMENSIONAL FUND ADVISORS LP |
| <0.01% | <0.01% | #47 | $178.4万 | 19.0万股 | $128.1万 | 13.7万股 | +5.4万股+39.25% | 加仓 |
| Exome Asset Management LLC |
| 1.07% | 1.14% | #4 | $173.4万 | 18.5万股 | $219.9万 | 23.4万股 | -4.9万股-21.02% | 减仓 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #58 | $159.8万 | 17.0万股 | $95.6万 | 10.2万股 | +6.9万股+67.33% | 加仓 |
| 未来资产环球ETFMIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
| <0.01% | <0.01% | #31 | $142.2万 | 15.2万股 | $150.7万 | 16.0万股 | -8,822股-5.50% | 减仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #57 | $117.2万 | 12.5万股 | $39.0万 | 4.2万股 | +8.3万股+200.95% | 加仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #50 | $105.4万 | 11.2万股 | $90.4万 | 9.6万股 | +1.6万股+16.79% | 加仓 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #76 | $104.4万 | 11.1万股 | $22.9万 | 2.4万股 | +8.7万股+356.81% | 加仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | 0.01% | #32 | $104.0万 | 11.1万股 | $325.8万 | 34.7万股 | -23.6万股-68.06% | 减仓 |
| Simplex交易SIMPLEX TRADING, LLC |
| <0.01% | <0.01% | #38 | $101.5万 | 10.8万股 | $49.6万 | 5.3万股 | +5.5万股+104.78% | 加仓 |
| DAFNA Capital Management LLC |
| 0.19% | — | #12 | $101.1万 | 10.8万股 | $0 | 0股 | +10.8万股 | 新买入 |
| Persistent Asset Partners Ltd |
| 0.29% | 0.42% | #10 | $95.7万 | 7.9万股 | $113.0万 | 11.2万股 | -3.3万股-29.58% | 减仓 |
| 咨询服务网络Advisory Services Network, LLC |
| 0.01% | <0.01% | #21 | $84.4万 | 9.0万股 | $131 | 14股 | +9.0万股+642,407.14% | 加仓 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| <0.01% | <0.01% | #39 | $74.4万 | 7.9万股 | $137.7万 | 14.7万股 | -6.7万股-45.88% | 减仓 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #46 | $73.3万 | 7.8万股 | $9.8万 | 1.0万股 | +6.8万股+644.78% | 加仓 |
| 萨斯奎汉纳组合策略Susquehanna Portfolio Strategies, LLC |
| 0.01% | — | #20 | $71.3万 | 7.6万股 | $0 | 0股 | +7.6万股 | 新买入 |
| XTX资本XTX Topco Ltd |
| 0.01% | 0.01% | #22 | $63.5万 | 6.8万股 | $35.7万 | 3.8万股 | +3.0万股+77.93% | 加仓 |
| Verdad Advisers, LP |
| 0.57% | 0.53% | #7 | $59.7万 | 6.4万股 | $47.2万 | 5.0万股 | +1.3万股+26.57% | 加仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #74 | $59.0万 | 6.3万股 | $87.4万 | 9.3万股 | -3.0万股-32.49% | 减仓 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | — | #68 | $52.0万 | 5.5万股 | $0 | 0股 | +5.5万股 | 新买入 |
| 汇丰控股HSBC HOLDINGS PLC |
| <0.01% | — | #53 | $50.5万 | 5.5万股 | $0 | 0股 | +5.5万股 | 新买入 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #71 | $45.8万 | 4.9万股 | $36.3万 | 3.9万股 | +1.0万股+26.29% | 加仓 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| <0.01% | — | #67 | $42.5万 | 4.5万股 | $0 | 0股 | +4.5万股 | 新买入 |
| Rangeley Capital, LLC |
| 0.39% | 0.41% | #8 | $41.3万 | 4.4万股 | $42.1万 | 4.5万股 | -840股-1.87% | 减仓 |
| 康托·菲茨杰拉德CANTOR FITZGERALD, L. P. |
| <0.01% | 0.01% | #24 | $37.6万 | 4.0万股 | $37.7万 | 4.0万股 | 00.00% | 持仓不变 |
| Driehaus资本管理DRIEHAUS CAPITAL MANAGEMENT LLC |
| <0.01% | — | #29 | $36.6万 | 3.9万股 | $0 | 0股 | +3.9万股 | 新买入 |
| ACADIAN ASSET MANAGEMENT LLC |
| <0.01% | <0.01% | #43 | $35.1万 | 3.7万股 | $101.6万 | 10.9万股 | -7.1万股-65.63% | 减仓 |
| LMR合伙人LMR Partners LLP |
| <0.01% | — | #34 | $33.3万 | 3.6万股 | $0 | 0股 | +3.6万股 | 新买入 |
| 工程师之门Engineers Gate Manager LP |
| <0.01% | <0.01% | #25 | $28.0万 | 3.0万股 | $13.3万 | 1.4万股 | +1.6万股+109.86% | 加仓 |
| 普信集团PRICE T ROWE ASSOCIATES INC /MD/ |
| <0.01% | <0.01% | #80 | $24.6万 | 2.6万股 | $11.9万 | 1.3万股 | +1.4万股+108.96% | 加仓 |
| Velan Capital Investment Management LP |
| 0.15% | 0.15% | #13 | $24.4万 | 2.6万股 | $24.4万 | 2.6万股 | 00.00% | 持仓不变 |
| 跳跃金融Jump Financial, LLC |
| <0.01% | <0.01% | #30 | $24.2万 | 2.6万股 | $28.7万 | 3.1万股 | -4,800股-15.69% | 减仓 |
| Pale Fire Capital SE |
| 0.02% | 0.02% | #19 | $22.8万 | 2.4万股 | $20.0万 | 2.1万股 | +2,951股+13.82% | 加仓 |
| Y截距(香港)Y-Intercept (Hong Kong) Ltd |
| <0.01% | — | #23 | $21.2万 | 2.3万股 | $0 | 0股 | +2.3万股 | 新买入 |
| 美国世纪投资AMERICAN CENTURY COMPANIES INC |
| <0.01% | <0.01% | #64 | $21.1万 | 2.3万股 | $14.2万 | 1.5万股 | +7,368股+48.67% | 加仓 |
