| Adage资本合伙人ADAGE CAPITAL PARTNERS GP, L.L.C. |
| 0.02% | 0.02% | #23 | $1,677.0万 | 901.6万股 | $1,013.1万 | 625.3万股 | +276.2万股+44.17% | 加仓 |
| 安本标准投资Aberdeen Group plc |
| 0.02% | 0.01% | #24 | $1,661.4万 | 893.3万股 | $537.3万 | 331.7万股 | +561.6万股+169.30% | 加仓 |
| Affinity Asset Advisors, LLC |
| 0.47% | 0.21% | #8 | $1,031.2万 | 554.4万股 | $397.6万 | 245.4万股 | +309.0万股+125.89% | 加仓 |
| Privium Fund Management B.V. |
| 1.89% | 1.84% | #2 | $1,026.7万 | 552.0万股 | $885.7万 | 546.7万股 | +5.3万股+0.97% | 加仓 |
| Ikarian Capital, LLC |
| 0.68% | 0.2% | #5 | $637.2万 | 342.6万股 | $241.7万 | 149.2万股 | +193.4万股+129.58% | 加仓 |
| Woodline合伙人Woodline Partners LP |
| 0.02% | — | #26 | $609.5万 | 327.7万股 | $0 | 0股 | +327.7万股 | 新买入 |
| HEIGHTS CAPITAL MANAGEMENT, INC |
| 1.19% | — | #3 | $513.8万 | 276.2万股 | $0 | 0股 | +276.2万股 | 新买入 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #50 | $328.7万 | 176.7万股 | $618.0万 | 290.1万股 | -113.4万股-39.09% | 减仓 |
| SPHERA FUNDS MANAGEMENT LTD. |
| 0.43% | — | #9 | $326.9万 | 175.7万股 | $0 | 0股 | +175.7万股 | 新买入 |
| Kynam Capital Management, LP |
| 0.16% | 0.16% | #11 | $291.3万 | 156.6万股 | $253.7万 | 156.6万股 | 00.00% | 持仓不变 |
| DAFNA Capital Management LLC |
| 0.54% | 0.58% | #6 | $284.6万 | 153.0万股 | $253.9万 | 156.8万股 | -3.7万股-2.37% | 减仓 |
| Squadron Capital Management LLC |
| 0.87% | — | #4 | $281.1万 | 151.1万股 | $0 | 0股 | +151.1万股 | 新买入 |
| 683 Capital Management, LLC |
| 0.13% | — | #13 | $259.1万 | 139.3万股 | $0 | 0股 | +139.3万股 | 新买入 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #48 | $220.3万 | 118.4万股 | $113.9万 | 70.3万股 | +48.1万股+68.39% | 加仓 |
| PLATINUM INVESTMENT MANAGEMENT LTD |
| 0.53% | 0.5% | #7 | $215.7万 | 115.9万股 | $200.2万 | 123.6万股 | -7.6万股-6.16% | 减仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #36 | $211.8万 | 113.9万股 | $148.9万 | 91.9万股 | +22.0万股+23.93% | 加仓 |
| Eversept Partners, LP |
| 0.1% | — | #15 | $190.1万 | 102.2万股 | $0 | 0股 | +102.2万股 | 新买入 |
| 布斯湾基金管理BOOTHBAY FUND MANAGEMENT, LLC |
| 0.02% | 0.01% | #22 | $176.5万 | 94.9万股 | $57.6万 | 35.5万股 | +59.3万股+167.04% | 加仓 |
| DIADEMA PARTNERS LP |
| 0.21% | 0.05% | #10 | $172.2万 | 92.6万股 | $29.2万 | 18.0万股 | +74.6万股+414.22% | 加仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #51 | $118.9万 | 63.9万股 | $49.5万 | 30.5万股 | +33.4万股+109.41% | 加仓 |
| 野村资产管理国际NOMURA ASSET MANAGEMENT INTERNATIONAL INC. |
| <0.01% | <0.01% | #35 | $115.3万 | 62.0万股 | $100.4万 | 62.0万股 | 00.00% | 持仓不变 |
| M28 Capital Management LP |
| 2.37% | 1.81% | #1 | $111.6万 | 60.0万股 | $97.2万 | 60.0万股 | 00.00% | 持仓不变 |
| 雷蒙德詹姆斯金融RAYMOND JAMES FINANCIAL INC |
| <0.01% | <0.01% | #47 | $106.2万 | 57.1万股 | $88.5万 | 54.6万股 | +2.5万股+4.58% | 加仓 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #54 | $84.6万 | 45.5万股 | $5.4万 | 3.3万股 | +42.2万股+1,267.13% | 加仓 |
| STEMPOINT CAPITAL LP |
| 0.11% | — | #14 | $80.2万 | 43.1万股 | $0 | 0股 | +43.1万股 | 新买入 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #49 | $51.3万 | 27.6万股 | $27.9万 | 17.2万股 | +10.3万股+59.93% | 加仓 |
| Monaco Asset Management SAM |
| 0.04% | 0.13% | #19 | $45.5万 | 24.4万股 | $67.8万 | 41.9万股 | -17.4万股-41.62% | 减仓 |
| Persistent Asset Partners Ltd |
| 0.14% | 0.03% | #12 | $44.0万 | 23.6万股 | $7.5万 | 4.6万股 | +19.0万股+413.28% | 加仓 |
| Palo Alto Investors LP |
| 0.05% | 0.05% | #16 | $35.1万 | 18.9万股 | $30.6万 | 18.9万股 | 00.00% | 持仓不变 |
| Burkehill Global 管理Burkehill Global Management, LP |
| 0.01% | — | #28 | $32.8万 | 17.6万股 | $0 | 0股 | +17.6万股 | 新买入 |
| GSA CAPITAL PARTNERS LLP |
| 0.02% | 0.01% | #25 | $32.3万 | 17.4万股 | $18.5万 | 11.4万股 | +6.0万股+52.15% | 加仓 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #53 | $29.9万 | 16.1万股 | $31.5万 | 19.4万股 | -3.3万股-17.11% | 减仓 |
| FRANKLIN STREET ADVISORS INC /NC |
| 0.02% | — | #27 | $27.9万 | 15.0万股 | $0 | 0股 | +15.0万股 | 新买入 |
| DEUTSCHE 银行 AG\DEUTSCHE BANK AG\ |
| <0.01% | <0.01% | #55 | $20.2万 | 10.9万股 | $17.6万 | 10.9万股 | 00.00% | 持仓不变 |
| OneDigital投资顾问OneDigital Investment Advisors LLC |
| <0.01% | <0.01% | #39 | $15.8万 | 8.5万股 | $13.8万 | 8.5万股 | 00.00% | 持仓不变 |
| 正交资本Quadrature Capital Ltd |
| <0.01% | <0.01% | #38 | $15.8万 | 8.5万股 | $1.9万 | 1.2万股 | +7.3万股+604.66% | 加仓 |
| RFG顾问RFG Advisory, LLC |
| <0.01% | <0.01% | #34 | $11.9万 | 6.4万股 | $3.1万 | 1.9万股 | +4.5万股+236.84% | 加仓 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #60 | $10.8万 | 5.8万股 | $30.0万 | 18.5万股 | -12.7万股-68.65% | 减仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #62 | $10.8万 | 5.8万股 | $13.8万 | 8.5万股 | -2.7万股-31.70% | 减仓 |
| Point72资产管理Point72 Asset Management, L.P. |
| <0.01% | <0.01% | #52 | $9.4万 | 5.1万股 | $122.4万 | 75.6万股 | -70.5万股-93.30% | 减仓 |
| Keating Financial Advisory Services, Inc. |
| 0.01% | 0.01% | #29 | $8.8万 | 4.8万股 | $3.3万 | 2.1万股 | +2.7万股+131.37% | 加仓 |
| Velan Capital Investment Management LP |
| 0.05% | 0.05% | #17 | $8.4万 | 4.5万股 | $7.3万 | 4.5万股 | 00.00% | 持仓不变 |
| 古根海姆资本GUGGENHEIM CAPITAL LLC |
| <0.01% | <0.01% | #44 | $7.4万 | 4.0万股 | $4.5万 | 2.8万股 | +1.2万股+44.53% | 加仓 |
| Steward合伙人投资顾问Steward Partners Investment Advisory, LLC |
| <0.01% | <0.01% | #46 | $6.6万 | 3.5万股 | $2,106 | 1,300股 | +3.4万股+2,610.85% | 加仓 |
| Axiom Investment Management LLC |
| 0.04% | 0.04% | #18 | $5.8万 | 3.1万股 | $5.3万 | 3.3万股 | -2,000股-6.06% | 减仓 |
| MOODY LYNN LIEBERSON & WALKER, LLC |
| <0.01% | <0.01% | #32 | $4.7万 | 2.5万股 | $4.1万 | 2.5万股 | 00.00% | 持仓不变 |
| 先锋领航个性化指数管理Vanguard Personalized Indexing Management, LLC |
| <0.01% | <0.01% | #45 | $4.1万 | 2.2万股 | $3.1万 | 1.9万股 | +2,685股+13.83% | 加仓 |
| MarinerMariner, LLC |
| <0.01% | <0.01% | #56 | $3.8万 | 2.0万股 | $3.3万 | 2.0万股 | 00.00% | 持仓不变 |
| Verdad Advisers, LP |
| 0.03% | — | #20 | $3.6万 | 1.9万股 | $0 | 0股 | +1.9万股 | 新买入 |
| NANO CAP NEW MILLENNIUM GROWTH FUND L P |
| 0.03% | 0.02% | #21 | $3.3万 | 1.8万股 | $1.6万 | 1.0万股 | +7,500股+75.00% | 加仓 |
