| 富达投资FMR LLC |
| <0.01% | <0.01% | #25 | $1,184.9万 | 274.3万股 | $1,052.8万 | 274.2万股 | +1,214股+0.04% | 加仓 |
| BML Capital Management, LLC |
| 6.21% | 4.69% | #1 | $1,088.5万 | 252.0万股 | $730.4万 | 190.2万股 | +61.8万股+32.46% | 加仓 |
| AQR资本管理AQR CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #18 | $431.6万 | 99.9万股 | $310.4万 | 80.8万股 | +19.1万股+23.59% | 加仓 |
| 洞察顾问PERCEPTIVE ADVISORS LLC |
| 0.05% | 0.06% | #7 | $360.0万 | 83.3万股 | $320.0万 | 83.3万股 | 00.00% | 持仓不变 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #43 | $337.0万 | 78.0万股 | $293.3万 | 76.4万股 | +1.6万股+2.14% | 加仓 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #32 | $287.6万 | 66.6万股 | $364.6万 | 94.9万股 | -28.4万股-29.87% | 减仓 |
| PFM Health Sciences, LP |
| 0.22% | 0.21% | #4 | $251.5万 | 58.2万股 | $228.3万 | 59.5万股 | -1.3万股-2.10% | 减仓 |
| Ensign Peak顾问Ensign Peak Advisors, Inc |
| <0.01% | <0.01% | #15 | $187.6万 | 43.4万股 | $202.2万 | 52.7万股 | -9.2万股-17.52% | 减仓 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #67 | $180.7万 | 41.8万股 | $485.1万 | 126.3万股 | -84.5万股-66.89% | 减仓 |
| Assenagon资产管理Assenagon Asset Management S.A. |
| <0.01% | <0.01% | #17 | $146.6万 | 33.9万股 | $193.6万 | 50.4万股 | -16.5万股-32.66% | 减仓 |
| Peapod Lane Capital LLC |
| 0.97% | — | #3 | $143.4万 | 33.2万股 | $0 | 0股 | +33.2万股 | 新买入 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| <0.01% | — | #23 | $91.6万 | 21.2万股 | $0 | 0股 | +21.2万股 | 新买入 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #54 | $88.5万 | 20.5万股 | $161.8万 | 42.1万股 | -21.7万股-51.43% | 减仓 |
| Stratos财富合伙人Stratos Wealth Partners, LTD. |
| 0.01% | 0.01% | #11 | $86.6万 | 20.1万股 | $77.0万 | 20.1万股 | 00.00% | 持仓不变 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #39 | $82.2万 | 19.0万股 | $97.0万 | 25.2万股 | -6.2万股-24.64% | 减仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #57 | $78.6万 | 18.2万股 | $611.6万 | 43.3万股 | -25.1万股-57.99% | 减仓 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | — | #28 | $78.5万 | 18.2万股 | $0 | 0股 | +18.2万股 | 新买入 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #45 | $74.9万 | 17.3万股 | $35.9万 | 9.3万股 | +8.0万股+85.80% | 加仓 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #53 | $60.1万 | 13.9万股 | $66.9万 | 17.4万股 | -3.5万股-20.05% | 减仓 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #55 | $55.5万 | 12.9万股 | $115.5万 | 30.1万股 | -17.2万股-57.27% | 减仓 |
| XTX资本XTX Topco Ltd |
| 0.01% | 0.01% | #12 | $53.9万 | 12.5万股 | $54.7万 | 14.2万股 | -1.8万股-12.47% | 减仓 |
| Catalio Capital Management, LP |
| 0.1% | 0.09% | #6 | $51.1万 | 11.8万股 | $45.4万 | 11.8万股 | 00.00% | 持仓不变 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #37 | $49.6万 | 11.5万股 | $42.9万 | 11.2万股 | +3,273股+2.93% | 加仓 |
| GMT CAPITAL CORP |
| 0.02% | 0.01% | #10 | $42.4万 | 9.8万股 | $16.3万 | 4.2万股 | +5.6万股+131.27% | 加仓 |
| 维度基金顾问DIMENSIONAL FUND ADVISORS LP |
| <0.01% | <0.01% | #44 | $39.2万 | 9.1万股 | $43.5万 | 11.3万股 | -2.3万股-19.99% | 减仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #58 | $36.1万 | 8.4万股 | $135.6万 | 35.3万股 | -27.0万股-76.34% | 减仓 |
| PURA VIDA INVESTMENTS, LLC |
| 0.97% | 2.15% | #2 | $36.0万 | 8.3万股 | $32.0万 | 8.3万股 | 00.00% | 持仓不变 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #77 | $35.1万 | 8.1万股 | $128.6万 | 33.5万股 | -25.4万股-75.76% | 减仓 |
| C WorldWide Group Holding A/S |
| 0.01% | 0.01% | #13 | $28.8万 | 6.7万股 | $25.6万 | 6.7万股 | 00.00% | 持仓不变 |
| IEQ资本IEQ CAPITAL, LLC |
| <0.01% | <0.01% | #20 | $22.5万 | 5.2万股 | $15.3万 | 4.0万股 | +1.2万股+31.18% | 加仓 |
| Marquette Asset Management, LLC |
| 0.03% | — | #9 | $21.2万 | 4.9万股 | $0 | 0股 | +4.9万股 | 新买入 |
| 加拿大国家银行NATIONAL BANK OF CANADA /FI/ |
| <0.01% | <0.01% | #34 | $19.7万 | 4.6万股 | $17.7万 | 4.6万股 | -542股-1.17% | 减仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #69 | $18.8万 | 4.4万股 | $48.2万 | 12.5万股 | -8.2万股-65.26% | 减仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #29 | $18.8万 | 4.3万股 | $85.3万 | 22.2万股 | -17.9万股-80.44% | 减仓 |
| 巴克莱BARCLAYS PLC |
| <0.01% | <0.01% | #61 | $18.5万 | 4.3万股 | $4.1万 | 1.1万股 | +3.2万股+296.32% | 加仓 |
| Centiva资本Centiva Capital, LP |
| <0.01% | <0.01% | #19 | $17.2万 | 4.0万股 | $19.5万 | 5.1万股 | -1.1万股-21.56% | 减仓 |
| Clayton Partners LLC |
| 0.11% | — | #5 | $16.2万 | 3.8万股 | $0 | 0股 | +3.8万股 | 新买入 |
| 普信集团PRICE T ROWE ASSOCIATES INC /MD/ |
| <0.01% | <0.01% | #74 | $15.4万 | 3.6万股 | $15.2万 | 3.9万股 | -3,805股-9.65% | 减仓 |
| ACADIAN ASSET MANAGEMENT LLC |
| <0.01% | <0.01% | #33 | $15.1万 | 3.5万股 | $14.9万 | 4.0万股 | -4,705股-11.83% | 减仓 |
| Jain GlobalJain Global LLC |
| <0.01% | — | #24 | $14.3万 | 3.3万股 | $0 | 0股 | +3.3万股 | 新买入 |
| HRT金融HRT FINANCIAL LP |
| <0.01% | — | #30 | $14.2万 | 3.3万股 | $0 | 0股 | +3.3万股 | 新买入 |
| MarinerMariner, LLC |
| <0.01% | <0.01% | #36 | $14.0万 | 3.2万股 | $7.1万 | 1.8万股 | +1.4万股+75.49% | 加仓 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #47 | $12.4万 | 2.9万股 | $16.5万 | 4.3万股 | -1.4万股-33.35% | 减仓 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| <0.01% | <0.01% | #71 | $12.1万 | 2.8万股 | $23.9万 | 6.2万股 | -3.4万股-55.26% | 减仓 |
| 美国世纪投资AMERICAN CENTURY COMPANIES INC |
| <0.01% | <0.01% | #52 | $11.6万 | 2.7万股 | $10.3万 | 2.7万股 | 00.00% | 持仓不变 |
| 桥道资本管理BRIDGEWAY CAPITAL MANAGEMENT, LLC |
| <0.01% | — | #16 | $10.8万 | 2.5万股 | $0 | 0股 | +2.5万股 | 新买入 |
| 蒙特利尔银行BANK OF MONTREAL /CAN/ |
| <0.01% | <0.01% | #60 | $10.7万 | 2.5万股 | $26.5万 | 1.8万股 | +6,666股+37.01% | 加仓 |
| SquarepointSquarepoint Ops LLC |
| <0.01% | — | #38 | $9.8万 | 2.3万股 | $0 | 0股 | +2.3万股 | 新买入 |
| Simplex交易SIMPLEX TRADING, LLC |
| <0.01% | <0.01% | #51 | $8.8万 | 2.0万股 | $2.7万 | 7,017股 | +1.3万股+189.30% | 加仓 |
| Catalyst Funds Management Pty Ltd |
| <0.01% | — | #14 | $8.3万 | 1.9万股 | $0 | 0股 | +1.9万股 | 新买入 |
