| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #61 | $1,375.6万 | 781.6万股 | $407.2万 | 214.3万股 | +567.3万股+264.70% | 加仓 |
| PFIZER INC |
| 4.63% | 3.5% | #1 | $788.0万 | 469.0万股 | $834.9万 | 469.0万股 | 00.00% | 持仓不变 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #65 | $740.7万 | 420.9万股 | $715.8万 | 376.7万股 | +44.1万股+11.72% | 加仓 |
| 麦肯齐金融MACKENZIE FINANCIAL CORP |
| 0.01% | <0.01% | #18 | $642.5万 | 365.1万股 | $179.1万 | 94.3万股 | +270.8万股+287.23% | 加仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| 0.01% | 0.01% | #17 | $488.1万 | 277.4万股 | $492.2万 | 259.0万股 | +18.3万股+7.07% | 加仓 |
| Kynam Capital Management, LP |
| 0.24% | 0.29% | #4 | $440.6万 | 250.3万股 | $475.6万 | 250.3万股 | 00.00% | 持仓不变 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #59 | $418.1万 | 237.5万股 | $193.5万 | 101.8万股 | +135.7万股+133.30% | 加仓 |
| ACADIAN ASSET MANAGEMENT LLC |
| <0.01% | <0.01% | #24 | $312.3万 | 177.4万股 | $175.2万 | 92.5万股 | +84.9万股+91.83% | 加仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #74 | $287.4万 | 163.3万股 | $80.4万 | 42.3万股 | +121.0万股+285.79% | 加仓 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #64 | $248.3万 | 141.1万股 | $246.5万 | 129.7万股 | +11.4万股+8.77% | 加仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #37 | $184.1万 | 104.6万股 | $334.4万 | 176.0万股 | -71.4万股-40.55% | 减仓 |
| 维度基金顾问DIMENSIONAL FUND ADVISORS LP |
| <0.01% | <0.01% | #53 | $171.7万 | 97.5万股 | $127.8万 | 67.3万股 | +30.2万股+44.88% | 加仓 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #63 | $136.5万 | 77.6万股 | $106.3万 | 56.0万股 | +21.6万股+38.63% | 加仓 |
| 富达投资FMR LLC |
| <0.01% | <0.01% | #88 | $128.0万 | 72.7万股 | $137.6万 | 72.4万股 | +3,156股+0.44% | 加仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #66 | $125.5万 | 71.3万股 | $41.4万 | 21.8万股 | +49.5万股+227.45% | 加仓 |
| Maverick资本MAVERICK CAPITAL LTD |
| 0.01% | 0.01% | #13 | $114.8万 | 65.3万股 | $124.0万 | 65.3万股 | 00.00% | 持仓不变 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | — | #93 | $108.0万 | 61.4万股 | $0 | 0股 | +61.4万股 | 新买入 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #57 | $106.7万 | 60.6万股 | $98.8万 | 52.0万股 | +8.6万股+16.59% | 加仓 |
| Qube研究科技Qube Research & Technologies Ltd |
| <0.01% | <0.01% | #38 | $96.1万 | 54.6万股 | $33.6万 | 17.7万股 | +36.9万股+208.86% | 加仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #68 | $91.1万 | 51.7万股 | $49.2万 | 25.9万股 | +25.8万股+99.63% | 加仓 |
| 72 Investment Holdings, LLC |
| 1.67% | 1.82% | #2 | $83.4万 | 47.4万股 | $90.1万 | 47.4万股 | 00.00% | 持仓不变 |
| GSA CAPITAL PARTNERS LLP |
| 0.05% | 0.06% | #10 | $81.6万 | 46.3万股 | $91.3万 | 48.1万股 | -1.7万股-3.60% | 减仓 |
| Jacobs Levy股票管理JACOBS LEVY EQUITY MANAGEMENT, INC |
| <0.01% | <0.01% | #28 | $72.3万 | 41.1万股 | $68.2万 | 35.9万股 | +5.2万股+14.50% | 加仓 |
| Cambridge Investment Research Advisors, Inc. |
| <0.01% | <0.01% | #33 | $67.3万 | 38.2万股 | $103.9万 | 54.7万股 | -16.5万股-30.09% | 减仓 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| <0.01% | <0.01% | #41 | $66.1万 | 37.6万股 | $229.1万 | 120.6万股 | -83.0万股-68.84% | 减仓 |
| Green Alpha Advisors, LLC |
| 0.43% | 0.7% | #3 | $64.1万 | 36.4万股 | $71.0万 | 37.4万股 | -9,326股-2.50% | 减仓 |
| PFM Health Sciences, LP |
| 0.05% | 0.17% | #9 | $62.4万 | 35.5万股 | $182.0万 | 95.8万股 | -60.3万股-62.97% | 减仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #92 | $56.8万 | 32.3万股 | $71.6万 | 37.7万股 | -5.4万股-14.26% | 减仓 |
| 景顺Invesco Ltd. |
| <0.01% | <0.01% | #97 | $53.0万 | 30.1万股 | $15.9万 | 8.4万股 | +21.8万股+260.61% | 加仓 |
| 富国银行WELLS FARGO & COMPANY/MN |
| <0.01% | <0.01% | #75 | $52.5万 | 29.8万股 | $57.7万 | 30.4万股 | -5,340股-1.76% | 减仓 |
| XTX资本XTX Topco Ltd |
| 0.01% | 0.01% | #19 | $47.4万 | 26.9万股 | $61.5万 | 32.3万股 | -5.4万股-16.79% | 减仓 |
| Bruce & Co., Inc. |
| 0.12% | 0.14% | #6 | $44.0万 | 25.0万股 | $47.5万 | 25.0万股 | 00.00% | 持仓不变 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #105 | $43.2万 | 24.5万股 | $199.0万 | 104.7万股 | -80.2万股-76.57% | 减仓 |
| 英仕曼集团Man Group plc |
| <0.01% | <0.01% | #39 | $42.3万 | 24.0万股 | $14.7万 | 7.7万股 | +16.3万股+210.93% | 加仓 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| <0.01% | <0.01% | #83 | $39.2万 | 22.3万股 | $2.4万 | 1.3万股 | +21.0万股+1,678.91% | 加仓 |
| MILESTONE ASSET MANAGEMENT, LLC |
| 0.06% | 0.06% | #8 | $35.2万 | 20.0万股 | $30.8万 | 16.2万股 | +3.8万股+23.45% | 加仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #99 | $34.8万 | 19.8万股 | $56.6万 | 29.8万股 | -10.0万股-33.60% | 减仓 |
| 未来资产环球ETFMIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
| <0.01% | <0.01% | #48 | $30.5万 | 17.3万股 | $16.8万 | 8.8万股 | +8.5万股+95.93% | 加仓 |
| 萨斯奎汉纳组合策略Susquehanna Portfolio Strategies, LLC |
| <0.01% | — | #22 | $27.9万 | 15.9万股 | $0 | 0股 | +15.9万股 | 新买入 |
| 格雷厄姆资本管理Graham Capital Management, L.P. |
| <0.01% | <0.01% | #20 | $27.4万 | 15.6万股 | $7.4万 | 3.9万股 | +11.7万股+302.35% | 加仓 |
| 美国世纪投资AMERICAN CENTURY COMPANIES INC |
| <0.01% | <0.01% | #69 | $24.7万 | 14.1万股 | $21.4万 | 11.2万股 | +2.8万股+25.01% | 加仓 |
| 桥道资本管理BRIDGEWAY CAPITAL MANAGEMENT, LLC |
| <0.01% | 0.01% | #23 | $23.2万 | 13.2万股 | $25.1万 | 13.2万股 | 00.00% | 持仓不变 |
| 纽文Nuveen, LLC |
| <0.01% | — | #90 | $21.7万 | 12.4万股 | $0 | 0股 | +12.4万股 | 新买入 |
| LPL金融LPL Financial LLC |
| <0.01% | <0.01% | #94 | $21.6万 | 12.3万股 | $6.7万 | 3.5万股 | +8.8万股+248.06% | 加仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #122 | $21.4万 | 12.1万股 | $83.5万 | 35.8万股 | -23.7万股-66.13% | 减仓 |
| NANO CAP NEW MILLENNIUM GROWTH FUND L P |
| 0.16% | 0.21% | #5 | $20.7万 | 11.8万股 | $22.3万 | 11.8万股 | 00.00% | 持仓不变 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #118 | $20.1万 | 11.4万股 | $21.2万 | 11.1万股 | +2,456股+2.20% | 加仓 |
| DEUTSCHE 银行 AG\DEUTSCHE BANK AG\ |
| <0.01% | — | #95 | $15.8万 | 9.0万股 | $0 | 0股 | +9.0万股 | 新买入 |
| 正交资本Quadrature Capital Ltd |
| <0.01% | <0.01% | #36 | $15.7万 | 8.9万股 | $7.5万 | 4.0万股 | +4.9万股+124.94% | 加仓 |
| 加拿大养老金计划投资委员会(CPPIB)CANADA PENSION PLAN INVESTMENT BOARD |
| <0.01% | <0.01% | #77 | $14.3万 | 8.1万股 | $11.0万 | 5.8万股 | +2.3万股+40.07% | 加仓 |
