| RA资本管理RA CAPITAL MANAGEMENT, L.P. |
| 0.16% | 0.11% | #10 | $1,873.3万 | 191.7万股 | $1,068.0万 | 191.7万股 | 00.00% | 持仓不变 |
| Adage资本合伙人ADAGE CAPITAL PARTNERS GP, L.L.C. |
| 0.02% | 0.02% | #21 | $1,486.3万 | 152.1万股 | $1,006.1万 | 180.6万股 | -28.5万股-15.78% | 减仓 |
| ACORN CAPITAL ADVISORS, LLC |
| 4.05% | 0.46% | #2 | $1,483.2万 | 151.8万股 | $160.3万 | 28.8万股 | +123.0万股+427.44% | 加仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #42 | $1,391.9万 | 142.5万股 | $527.8万 | 94.8万股 | +47.7万股+50.35% | 加仓 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #61 | $1,386.2万 | 141.9万股 | $136.4万 | 24.5万股 | +117.4万股+479.34% | 加仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #62 | $936.9万 | 95.9万股 | $412.0万 | 74.0万股 | +21.9万股+29.64% | 加仓 |
| Catalio Capital Management, LP |
| 1.73% | 1.04% | #3 | $919.2万 | 94.1万股 | $500.0万 | 89.8万股 | +4.3万股+4.81% | 加仓 |
| Avidity Partners Management LP |
| 1.45% | 0.52% | #4 | $903.2万 | 92.4万股 | $258.3万 | 46.4万股 | +46.1万股+99.35% | 加仓 |
| 普信投资管理T. Rowe Price Investment Management, Inc. |
| 0.01% | 0.01% | #31 | $768.2万 | 78.6万股 | $859.0万 | 154.2万股 | -75.6万股-49.01% | 减仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #32 | $679.3万 | 69.5万股 | $84.2万 | 15.1万股 | +54.4万股+359.73% | 加仓 |
| Kalehua Capital Management LLC |
| 4.8% | — | #1 | $669.9万 | 68.6万股 | $0 | 0股 | +68.6万股 | 新买入 |
| NEA Management Company, LLC |
| 0.35% | — | #6 | $563.5万 | 57.7万股 | $0 | 0股 | +57.7万股 | 新买入 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #53 | $533.1万 | 54.6万股 | $732.5万 | 131.5万股 | -76.9万股-58.50% | 减仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #60 | $519.1万 | 53.1万股 | $114.9万 | 20.6万股 | +32.5万股+157.71% | 加仓 |
| 吉萨洛资本管理Ghisallo Capital Management LLC |
| 0.03% | — | #19 | $488.5万 | 50.0万股 | $0 | 0股 | +50.0万股 | 新买入 |
| Soleus 资本管理Soleus Capital Management, L.P. |
| 0.15% | 0.1% | #11 | $429.9万 | 44.0万股 | $245.1万 | 44.0万股 | 00.00% | 持仓不变 |
| Caption管理Caption Management, LLC |
| 0.02% | 0.04% | #23 | $369.5万 | 37.8万股 | $658.3万 | 118.2万股 | -80.4万股-68.00% | 减仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #51 | $345.4万 | 35.4万股 | $108.1万 | 19.4万股 | +16.0万股+82.22% | 加仓 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #43 | $333.8万 | 34.2万股 | $284.9万 | 51.2万股 | -17.0万股-33.21% | 减仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #75 | $318.5万 | 32.6万股 | $45.0万 | 8.1万股 | +24.5万股+303.74% | 加仓 |
| Affinity Asset Advisors, LLC |
| 0.14% | 0.14% | #13 | $305.3万 | 31.3万股 | $278.5万 | 50.0万股 | -18.8万股-37.50% | 减仓 |
| Brevan Howard资本管理Brevan Howard Capital Management LP |
| 0.02% | 0.01% | #22 | $302.7万 | 31.0万股 | $118.3万 | 21.2万股 | +9.7万股+45.89% | 加仓 |
| Boxer Capital Management, LLC |
| 0.22% | 0.22% | #8 | $295.6万 | 30.3万股 | $168.5万 | 30.3万股 | 00.00% | 持仓不变 |
| 戴维森·肯普纳资本DAVIDSON KEMPNER CAPITAL MANAGEMENT LP |
| 0.03% | 0.02% | #17 | $293.1万 | 30.0万股 | $167.1万 | 30.0万股 | 00.00% | 持仓不变 |
| ACADIAN ASSET MANAGEMENT LLC |
| <0.01% | <0.01% | #35 | $292.1万 | 29.9万股 | $138.2万 | 24.9万股 | +5.0万股+20.10% | 加仓 |
| SILVERARC CAPITAL MANAGEMENT, LLC |
| 0.3% | — | #7 | $290.6万 | 29.7万股 | $0 | 0股 | +29.7万股 | 新买入 |
| Eversept Partners, LP |
| 0.14% | 0.09% | #12 | $269.8万 | 27.6万股 | $167.1万 | 30.0万股 | -2.4万股-7.93% | 减仓 |
| Tetragon Partners GP Ltd |
| 0.39% | 0.11% | #5 | $244.5万 | 25.0万股 | $57.4万 | 10.3万股 | +14.7万股+143.05% | 加仓 |
| 摩根大通JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #71 | $209.4万 | 20.8万股 | $2,496 | 471股 | +20.7万股+43,978.34% | 加仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #73 | $197.8万 | 20.3万股 | $16.9万 | 2.6万股 | +17.7万股+685.94% | 加仓 |
| Trexquant投资Trexquant Investment LP |
| 0.01% | 0.01% | #27 | $184.0万 | 18.8万股 | $143.7万 | 25.8万股 | -7.0万股-26.96% | 减仓 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #45 | $183.7万 | 18.8万股 | $468 | 84股 | +18.8万股+223,754.76% | 加仓 |
| DLD Asset Management, LP |
| 0.12% | — | #16 | $177.1万 | 18.2万股 | $0 | 0股 | +18.2万股 | 新买入 |
| 巴克莱BARCLAYS PLC |
| <0.01% | <0.01% | #58 | $162.1万 | 16.6万股 | $4.1万 | 7,424股 | +15.8万股+2,134.70% | 加仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #63 | $156.3万 | 16.0万股 | $21.5万 | 3.9万股 | +12.1万股+315.00% | 加仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #57 | $142.1万 | 14.5万股 | $64.0万 | 11.5万股 | +3.0万股+26.51% | 加仓 |
| J. Goldman & Co LP |
| 0.03% | — | #18 | $132.0万 | 13.5万股 | $0 | 0股 | +13.5万股 | 新买入 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | — | #83 | $131.7万 | 13.5万股 | $0 | 0股 | +13.5万股 | 新买入 |
| SILVERBACK ASSET MANAGEMENT LLC |
| 0.14% | 0.13% | #14 | $127.0万 | 13.0万股 | $91.9万 | 16.5万股 | -3.5万股-21.21% | 减仓 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| <0.01% | <0.01% | #44 | $125.5万 | 12.8万股 | $71.5万 | 12.8万股 | 00.00% | 持仓不变 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #67 | $115.3万 | 11.8万股 | $282.7万 | 50.8万股 | -39.0万股-76.75% | 减仓 |
| Group One交易GROUP ONE TRADING LLC |
| <0.01% | <0.01% | #39 | $114.9万 | 11.8万股 | $106.7万 | 19.2万股 | -7.4万股-38.60% | 减仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #40 | $105.7万 | 10.8万股 | $58.7万 | 10.5万股 | +2,800股+2.66% | 加仓 |
| C WorldWide Group Holding A/S |
| 0.02% | 0.01% | #20 | $97.7万 | 10.0万股 | $55.7万 | 10.0万股 | 00.00% | 持仓不变 |
| 跳跃金融Jump Financial, LLC |
| 0.01% | 0.02% | #29 | $91.8万 | 9.4万股 | $146.0万 | 26.2万股 | -16.8万股-64.14% | 减仓 |
| 景顺Invesco Ltd. |
| <0.01% | <0.01% | #81 | $88.2万 | 9.0万股 | $9.3万 | 1.7万股 | +7.4万股+439.51% | 加仓 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #80 | $84.3万 | 8.6万股 | $330.7万 | 59.4万股 | -50.7万股-85.47% | 减仓 |
| Connor Clark & Lunn投资管理Connor, Clark & Lunn Investment Management Ltd. |
| <0.01% | <0.01% | #41 | $74.6万 | 7.6万股 | $44.0万 | 7.9万股 | -2,684股-3.39% | 减仓 |
| 桥道资本管理BRIDGEWAY CAPITAL MANAGEMENT, LLC |
| 0.01% | 0.01% | #26 | $70.2万 | 7.2万股 | $40.0万 | 7.2万股 | 00.00% | 持仓不变 |
| SquarepointSquarepoint Ops LLC |
| <0.01% | — | #47 | $62.3万 | 6.4万股 | $0 | 0股 | +6.4万股 | 新买入 |
