| 富达投资FMR LLC |
| <0.01% | <0.01% | #34 | $4,842.6万 | 970.5万股 | $5,110.8万 | 969.8万股 | +6,672股+0.07% | 加仓 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #56 | $2,182.6万 | 437.4万股 | $794.3万 | 150.7万股 | +286.7万股+190.20% | 加仓 |
| Sanofi |
| 2.53% | 4.25% | #1 | $1,351.6万 | 270.9万股 | $1,427.4万 | 270.9万股 | 00.00% | 持仓不变 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | — | #65 | $1,140.9万 | 228.6万股 | $0 | 0股 | +228.6万股 | 新买入 |
| 普信集团PRICE T ROWE ASSOCIATES INC /MD/ |
| <0.01% | <0.01% | #43 | $966.1万 | 193.6万股 | $964.0万 | 182.9万股 | +10.7万股+5.84% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #54 | $684.2万 | 137.1万股 | $336.4万 | 63.8万股 | +73.3万股+114.87% | 加仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #70 | $500.0万 | 100.2万股 | $141.5万 | 26.9万股 | +73.3万股+273.15% | 加仓 |
| DCF Advisers, LLC |
| 0.7% | 0.2% | #3 | $394.2万 | 79.0万股 | $74.6万 | 14.1万股 | +64.9万股+458.45% | 加仓 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| <0.01% | 0.01% | #30 | $365.2万 | 73.2万股 | $1,052.2万 | 199.7万股 | -126.5万股-63.34% | 减仓 |
| Connor Clark & Lunn投资管理Connor, Clark & Lunn Investment Management Ltd. |
| 0.01% | <0.01% | #25 | $300.0万 | 60.1万股 | $211.0万 | 40.0万股 | +20.1万股+50.18% | 加仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #59 | $260.2万 | 52.1万股 | $278.8万 | 52.9万股 | -7,667股-1.45% | 减仓 |
| ALETHEA CAPITAL MANAGEMENT, LLC |
| 0.98% | 0.06% | #2 | $236.0万 | 47.3万股 | $12.1万 | 2.3万股 | +45.0万股+1,962.07% | 加仓 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #68 | $229.9万 | 46.1万股 | $171.8万 | 32.6万股 | +13.5万股+41.34% | 加仓 |
| 顶峰金融Summit Financial, LLC |
| 0.02% | 0.03% | #17 | $225.7万 | 45.2万股 | $198.5万 | 37.7万股 | +7.6万股+20.04% | 加仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #61 | $224.0万 | 44.9万股 | $198.3万 | 37.6万股 | +7.3万股+19.29% | 加仓 |
| 纽文Nuveen, LLC |
| <0.01% | — | #49 | $218.7万 | 43.8万股 | $0 | 0股 | +43.8万股 | 新买入 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #63 | $218.1万 | 43.7万股 | $62.0万 | 11.8万股 | +31.9万股+271.38% | 加仓 |
| LEVIN CAPITAL STRATEGIES, L.P. |
| 0.14% | <0.01% | #6 | $206.6万 | 41.4万股 | $5.3万 | 1.0万股 | +40.4万股+4,040.00% | 加仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | — | #53 | $180.0万 | 36.1万股 | $0 | 0股 | +36.1万股 | 新买入 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | — | #84 | $179.2万 | 35.9万股 | $0 | 0股 | +35.9万股 | 新买入 |
| GSA CAPITAL PARTNERS LLP |
| 0.11% | 0.03% | #9 | $171.3万 | 34.3万股 | $40.4万 | 7.7万股 | +26.7万股+347.29% | 加仓 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #48 | $164.9万 | 33.0万股 | $581.1万 | 110.3万股 | -77.2万股-70.04% | 减仓 |
| Burkehill Global 管理Burkehill Global Management, LP |
| 0.05% | 0.08% | #12 | $149.7万 | 30.0万股 | $158.1万 | 30.0万股 | 00.00% | 持仓不变 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #42 | $143.9万 | 28.8万股 | $129.0万 | 24.5万股 | +4.4万股+17.83% | 加仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #91 | $113.0万 | 22.6万股 | $206.4万 | 29.5万股 | -6.8万股-23.19% | 减仓 |
| Occam Crest Management LP |
| 0.62% | 1.74% | #4 | $112.9万 | 27.8万股 | $287.3万 | 54.5万股 | -26.7万股-48.91% | 减仓 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #83 | $106.1万 | 21.3万股 | $70.8万 | 13.4万股 | +7.8万股+58.29% | 加仓 |
| D.E.肖D. E. Shaw & Co., Inc. |
| <0.01% | — | #52 | $101.6万 | 20.4万股 | $0 | 0股 | +20.4万股 | 新买入 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #77 | $83.8万 | 16.8万股 | $19.7万 | 3.7万股 | +13.1万股+349.61% | 加仓 |
| Permanent Capital Management, LP |
| 0.1% | — | #10 | $74.9万 | 15.0万股 | $0 | 0股 | +15.0万股 | 新买入 |
| PVG ASSET MANAGEMENT CORP |
| 0.42% | 0.36% | #5 | $73.1万 | 14.6万股 | $61.5万 | 14.7万股 | -210股-0.14% | 减仓 |
| HighTower顾问HighTower Advisors, LLC |
| <0.01% | <0.01% | #45 | $71.6万 | 14.3万股 | $69.2万 | 13.1万股 | +1.2万股+9.29% | 加仓 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| <0.01% | — | #78 | $65.9万 | 13.2万股 | $0 | 0股 | +13.2万股 | 新买入 |
| Kingsview Wealth Management, LLC |
| 0.01% | 0.01% | #21 | $64.4万 | 12.2万股 | $64.4万 | 12.2万股 | 00.00% | 持仓不变 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #101 | $57.8万 | 11.6万股 | $79.5万 | 15.1万股 | -3.5万股-23.20% | 减仓 |
| 桥道资本管理BRIDGEWAY CAPITAL MANAGEMENT, LLC |
| 0.01% | 0.01% | #23 | $54.0万 | 10.8万股 | $62.3万 | 11.8万股 | -1.0万股-8.46% | 减仓 |
| Envestnet资产管理ENVESTNET ASSET MANAGEMENT INC |
| <0.01% | <0.01% | #76 | $52.8万 | 10.6万股 | $11.5万 | 2.2万股 | +8.4万股+383.96% | 加仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #98 | $48.0万 | 9.6万股 | $172.7万 | 32.8万股 | -23.1万股-70.63% | 减仓 |
| 费雪资产管理Fisher Asset Management, LLC |
| <0.01% | — | #75 | $44.1万 | 8.8万股 | $0 | 0股 | +8.8万股 | 新买入 |
| Corient私人财富Corient Private Wealth LLC |
| <0.01% | — | #60 | $38.5万 | 7.7万股 | $0 | 0股 | +7.7万股 | 新买入 |
| 阿默普莱斯金融AMERIPRISE FINANCIAL INC |
| <0.01% | — | #88 | $35.7万 | 7.1万股 | $0 | 0股 | +7.1万股 | 新买入 |
| Simplex交易SIMPLEX TRADING, LLC |
| <0.01% | <0.01% | #67 | $34.9万 | 7.0万股 | $4.7万 | 8,942股 | +6.1万股+682.82% | 加仓 |
| RhumbLine顾问RHUMBLINE ADVISERS |
| <0.01% | — | #64 | $32.9万 | 6.6万股 | $0 | 0股 | +6.6万股 | 新买入 |
| ALPS顾问ALPS ADVISORS INC |
| <0.01% | — | #40 | $32.8万 | 6.6万股 | $0 | 0股 | +6.6万股 | 新买入 |
| 道明资产管理TD ASSET MANAGEMENT INC |
| <0.01% | <0.01% | #62 | $32.5万 | 6.5万股 | $49.7万 | 9.4万股 | -2.9万股-30.89% | 减仓 |
| XTX资本XTX Topco Ltd |
| <0.01% | — | #26 | $32.1万 | 6.4万股 | $0 | 0股 | +6.4万股 | 新买入 |
| 宏利人寿MANUFACTURERS LIFE INSURANCE COMPANY, THE |
| <0.01% | <0.01% | #66 | $31.0万 | 6.2万股 | $36.8万 | 7.0万股 | -7,597股-10.89% | 减仓 |
| Clearstead顾问Clearstead Advisors, LLC |
| <0.01% | <0.01% | #31 | $30.4万 | 6.1万股 | $32.1万 | 6.1万股 | 00.00% | 持仓不变 |
| 美国世纪投资AMERICAN CENTURY COMPANIES INC |
| <0.01% | <0.01% | #74 | $29.7万 | 6.0万股 | $18.0万 | 3.4万股 | +2.5万股+74.02% | 加仓 |
| SquarepointSquarepoint Ops LLC |
| <0.01% | <0.01% | #57 | $28.8万 | 5.8万股 | $119.1万 | 22.6万股 | -16.8万股-74.48% | 减仓 |
