| Nantahala 资本管理Nantahala Capital Management, LLC |
| 1.27% | 1% | #4 | $3,804.7万 | 615.6万股 | $2,702.8万 | 603.3万股 | +12.3万股+2.05% | 加仓 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #68 | $2,071.8万 | 335.2万股 | $1,431.6万 | 319.6万股 | +15.7万股+4.91% | 加仓 |
| AIGH Capital Management LLC |
| 1.16% | 1.89% | #5 | $1,846.0万 | 298.7万股 | $1,388.8万 | 310.0万股 | -11.3万股-3.65% | 减仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #69 | $1,366.7万 | 221.1万股 | $969.9万 | 216.5万股 | +4.7万股+2.15% | 加仓 |
| Cable Car 资本Cable Car Capital, LP |
| 4.39% | 4.47% | #1 | $1,347.3万 | 300.7万股 | $1,347.3万 | 300.7万股 | 00.00% | 持仓不变 |
| OneDigital投资顾问OneDigital Investment Advisors LLC |
| 0.09% | — | #16 | $1,021.6万 | 165.3万股 | $0 | 0股 | +165.3万股 | 新买入 |
| AWM Investment Company, Inc. |
| 0.8% | 0.4% | #6 | $918.4万 | 148.6万股 | $359.8万 | 80.3万股 | +68.3万股+85.04% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #61 | $779.5万 | 126.1万股 | $542.2万 | 121.0万股 | +5.1万股+4.24% | 加仓 |
| 肯尼迪资本管理KENNEDY CAPITAL MANAGEMENT LLC |
| 0.14% | 0.12% | #13 | $766.4万 | 124.0万股 | $566.1万 | 126.4万股 | -2.3万股-1.86% | 减仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #52 | $756.9万 | 122.5万股 | $506.5万 | 113.1万股 | +9.4万股+8.33% | 加仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #73 | $642.9万 | 104.0万股 | $428.9万 | 95.7万股 | +8.3万股+8.66% | 加仓 |
| Propel Bio Management, LLC |
| 3.18% | 3.79% | #2 | $607.5万 | 98.3万股 | $600.8万 | 133.0万股 | -34.7万股-26.08% | 减仓 |
| NAN FUNG TRINITY (HK) Ltd |
| 0.58% | 0.47% | #7 | $591.3万 | 95.7万股 | $428.6万 | 95.7万股 | 00.00% | 持仓不变 |
| Diametric Capital, LP |
| 0.49% | 0.71% | #9 | $466.6万 | 75.5万股 | $274.0万 | 61.2万股 | +14.4万股+23.47% | 加仓 |
| J. Goldman & Co LP |
| 0.11% | 0.08% | #14 | $419.1万 | 67.8万股 | $287.0万 | 64.1万股 | +3.8万股+5.88% | 加仓 |
| SILVERARC CAPITAL MANAGEMENT, LLC |
| 0.39% | 0.3% | #10 | $377.2万 | 61.0万股 | $290.7万 | 64.9万股 | -3.9万股-5.94% | 减仓 |
| Rubric资本管理Rubric Capital Management LP |
| 0.03% | — | #23 | $376.2万 | 60.9万股 | $0 | 0股 | +60.9万股 | 新买入 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #70 | $372.9万 | 60.3万股 | $496.7万 | 110.9万股 | -50.5万股-45.58% | 减仓 |
| Stonepine Capital Management, LLC |
| 0.53% | 1.52% | #8 | $344.4万 | 55.7万股 | $379.3万 | 84.7万股 | -28.9万股-34.17% | 减仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #64 | $341.5万 | 55.3万股 | $195.3万 | 43.6万股 | +11.7万股+26.76% | 加仓 |
| 花旗集团CITIGROUP INC |
| <0.01% | <0.01% | #45 | $338.8万 | 54.8万股 | $234.1万 | 52.2万股 | +2.6万股+4.95% | 加仓 |
| 加拿大国家银行NATIONAL BANK OF CANADA /FI/ |
| <0.01% | <0.01% | #42 | $309.0万 | 50.0万股 | $224.0万 | 50.0万股 | 00.00% | 持仓不变 |
| 蒙塔诺瓦资本MONTANOVA CAPITAL, LLC |
| 0.06% | 0.31% | #18 | $309.0万 | 50.0万股 | $1,198.8万 | 267.6万股 | -217.6万股-81.32% | 减仓 |
| Knoll Capital Management, LLC |
| 1.72% | 1.15% | #3 | $300.0万 | 48.6万股 | $217.5万 | 48.6万股 | 00.00% | 持仓不变 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #67 | $280.8万 | 45.4万股 | $129.0万 | 28.8万股 | +16.6万股+57.76% | 加仓 |
| PanAgora资产管理PANAGORA ASSET MANAGEMENT INC |
| 0.01% | <0.01% | #35 | $252.8万 | 40.9万股 | $89.2万 | 19.9万股 | +21.0万股+105.42% | 加仓 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #78 | $230.1万 | 37.2万股 | $176.6万 | 39.4万股 | -2.2万股-5.55% | 减仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #86 | $225.9万 | 36.6万股 | $320.8万 | 60.8万股 | -24.2万股-39.84% | 减仓 |
| 都铎投资TUDOR INVESTMENT CORP ET AL |
| <0.01% | — | #40 | $223.0万 | 36.1万股 | $0 | 0股 | +36.1万股 | 新买入 |
| 巴克莱BARCLAYS PLC |
| <0.01% | <0.01% | #62 | $220.3万 | 35.6万股 | $12.2万 | 2.7万股 | +32.9万股+1,208.08% | 加仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #57 | $215.1万 | 34.8万股 | $152.1万 | 34.0万股 | +8,503股+2.50% | 加仓 |
| 简化资产管理Simplify Asset Management Inc. |
| 0.03% | 0.03% | #24 | $213.5万 | 34.5万股 | $227.6万 | 50.8万股 | -16.3万股-32.00% | 减仓 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #93 | $180.2万 | 29.2万股 | $121.4万 | 27.1万股 | +2.1万股+7.63% | 加仓 |
| Group One交易GROUP ONE TRADING LLC |
| <0.01% | <0.01% | #43 | $151.4万 | 24.5万股 | $93.9万 | 21.0万股 | +3.5万股+16.91% | 加仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #74 | $138.0万 | 22.3万股 | $104.8万 | 23.4万股 | -1.1万股-4.55% | 减仓 |
| ExodusPoint资本ExodusPoint Capital Management, LP |
| 0.01% | — | #33 | $131.2万 | 21.2万股 | $0 | 0股 | +21.2万股 | 新买入 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #59 | $130.6万 | 21.1万股 | $190.6万 | 42.5万股 | -21.4万股-50.32% | 减仓 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| <0.01% | <0.01% | #72 | $126.2万 | 20.4万股 | $86.7万 | 19.4万股 | +1.1万股+5.48% | 加仓 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| <0.01% | <0.01% | #46 | $120.4万 | 19.5万股 | $96.9万 | 21.6万股 | -2.1万股-9.93% | 减仓 |
| 富达投资FMR LLC |
| <0.01% | <0.01% | #107 | $85.6万 | 13.8万股 | $87.3万 | 19.5万股 | -5.6万股-28.91% | 减仓 |
| Headlands Technologies LLC |
| 0.08% | 0.03% | #17 | $77.3万 | 12.5万股 | $28.4万 | 6.3万股 | +6.2万股+97.47% | 加仓 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #87 | $74.5万 | 12.1万股 | $56.9万 | 12.7万股 | -6,595股-5.19% | 减仓 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #98 | $67.4万 | 10.9万股 | $63.7万 | 14.2万股 | -3.3万股-23.29% | 减仓 |
| Palo Alto Investors LP |
| 0.1% | 0.07% | #15 | $67.3万 | 10.9万股 | $48.8万 | 10.9万股 | 00.00% | 持仓不变 |
| SEI投资SEI INVESTMENTS CO |
| <0.01% | <0.01% | #55 | $65.2万 | 10.6万股 | $77.3万 | 17.2万股 | -6.7万股-38.79% | 减仓 |
| Gem Investment Advisors, LLC |
| 0.38% | — | #11 | $61.2万 | 9.9万股 | $0 | 0股 | +9.9万股 | 新买入 |
| Corient私人财富Corient Private Wealth LLC |
| <0.01% | — | #60 | $55.6万 | 9.0万股 | $0 | 0股 | +9.0万股 | 新买入 |
| 纽文Nuveen, LLC |
| <0.01% | <0.01% | #85 | $51.1万 | 8.3万股 | $25.4万 | 5.7万股 | +2.6万股+45.68% | 加仓 |
| Pale Fire Capital SE |
| 0.04% | 0.03% | #22 | $50.6万 | 8.2万股 | $31.3万 | 7.0万股 | +1.2万股+17.32% | 加仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| <0.01% | — | #66 | $49.9万 | 8.1万股 | $0 | 0股 | +8.1万股 | 新买入 |
