| 蒙塔诺瓦资本MONTANOVA CAPITAL, LLC |
| 0.92% | 0.03% | #6 | $5,050.3万 | 202.0万股 | $108.9万 | 3.5万股 | +198.6万股+5,747.07% | 加仓 |
| Avoro资本顾问Avoro Capital Advisors LLC |
| 0.32% | — | #14 | $3,610.1万 | 144.4万股 | $0 | 0股 | +144.4万股 | 新买入 |
| 贝克兄弟顾问BAKER BROS. ADVISORS LP |
| 0.16% | — | #18 | $3,216.0万 | 128.6万股 | $0 | 0股 | +128.6万股 | 新买入 |
| Balyasny资产管理BALYASNY ASSET MANAGEMENT L.P. |
| 0.03% | <0.01% | #23 | $2,605.5万 | 104.2万股 | $51.1万 | 1.6万股 | +102.6万股+6,331.34% | 加仓 |
| Cormorant Asset Management, LP |
| 1.31% | 0.48% | #4 | $2,570.6万 | 102.8万股 | $965.2万 | 30.6万股 | +72.2万股+235.78% | 加仓 |
| RA资本管理RA CAPITAL MANAGEMENT, L.P. |
| 0.16% | — | #19 | $1,805.1万 | 72.2万股 | $0 | 0股 | +72.2万股 | 新买入 |
| Vivo Capital, LLC |
| 1.65% | 1.89% | #3 | $1,805.1万 | 72.2万股 | $2,275.8万 | 72.2万股 | 00.00% | 持仓不变 |
| Logos Global Management LP |
| 0.78% | 0.05% | #8 | $1,805.1万 | 72.2万股 | $94.6万 | 3.0万股 | +69.2万股+2,306.73% | 加仓 |
| Fairmount Funds Management LLC |
| 1.19% | — | #5 | $1,805.1万 | 72.2万股 | $0 | 0股 | +72.2万股 | 新买入 |
| Caligan Partners LP |
| 0.74% | 0.26% | #9 | $1,573.7万 | 62.9万股 | $397.2万 | 12.6万股 | +50.3万股+399.57% | 加仓 |
| B Group, Inc. |
| 7.16% | — | #1 | $1,525.4万 | 61.0万股 | $0 | 0股 | +61.0万股 | 新买入 |
| Trails Edge Capital Partners, LP |
| 2.05% | 0.9% | #2 | $1,288.3万 | 51.5万股 | $394.0万 | 12.5万股 | +39.0万股+312.27% | 加仓 |
| 富兰克林资源FRANKLIN RESOURCES INC |
| <0.01% | <0.01% | #28 | $1,236.3万 | 49.5万股 | $420.8万 | 13.4万股 | +36.1万股+270.41% | 加仓 |
| Octagon Capital Advisors LP |
| 0.81% | — | #7 | $902.5万 | 36.1万股 | $0 | 0股 | +36.1万股 | 新买入 |
| ADAR1 Capital Management, LLC |
| 0.42% | — | #12 | $902.5万 | 36.1万股 | $0 | 0股 | +36.1万股 | 新买入 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| <0.01% | <0.01% | #26 | $516.3万 | 20.7万股 | $207.2万 | 6.6万股 | +14.1万股+214.18% | 加仓 |
| Boxer Capital Management, LLC |
| 0.34% | — | #13 | $451.3万 | 18.1万股 | $0 | 0股 | +18.1万股 | 新买入 |
| Patient Square Capital LP |
| 0.68% | — | #10 | $437.6万 | 17.5万股 | $0 | 0股 | +17.5万股 | 新买入 |
| Alyeska投资集团Alyeska Investment Group, L.P. |
| 0.01% | — | #24 | $361.0万 | 14.4万股 | $0 | 0股 | +14.4万股 | 新买入 |
| Affinity Asset Advisors, LLC |
| 0.16% | — | #17 | $361.0万 | 14.4万股 | $0 | 0股 | +14.4万股 | 新买入 |
| 布斯湾基金管理BOOTHBAY FUND MANAGEMENT, LLC |
| 0.04% | 0.01% | #22 | $334.1万 | 13.4万股 | $82.3万 | 2.6万股 | +10.8万股+411.57% | 加仓 |
| AWM Investment Company, Inc. |
| 0.24% | — | #15 | $278.4万 | 11.1万股 | $0 | 0股 | +11.1万股 | 新买入 |
| Richmond Investment Services, LLC |
| 0.63% | — | #11 | $199.3万 | 8.0万股 | $0 | 0股 | +8.0万股 | 新买入 |
| Ikarian Capital, LLC |
| 0.09% | 0.02% | #20 | $88.5万 | 3.5万股 | $20.0万 | 6,351股 | +2.9万股+457.17% | 加仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #32 | $53.9万 | 2.2万股 | $14.3万 | 4,529股 | +1.7万股+375.62% | 加仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #29 | $51.0万 | 2.0万股 | $101.0万 | 3.2万股 | -1.2万股-36.28% | 减仓 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #35 | $50.3万 | 2.0万股 | $28.0万 | 8,872股 | +1.1万股+126.75% | 加仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #38 | $43.3万 | 1.7万股 | $95 | 10股 | +1.7万股+173,190.00% | 加仓 |
| Catalio Capital Management, LP |
| 0.07% | 0.1% | #21 | $36.8万 | 1.5万股 | $46.4万 | 1.5万股 | 00.00% | 持仓不变 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #39 | $36.5万 | 1.5万股 | $30.0万 | 9,501股 | +5,115股+53.84% | 加仓 |
| SUPERSTRING CAPITAL MANAGEMENT LP |
| 0.22% | — | #16 | $35.4万 | 1.4万股 | $0 | 0股 | +1.4万股 | 新买入 |
| 巴克莱BARCLAYS PLC |
| <0.01% | — | #34 | $31.0万 | 1.2万股 | $0 | 0股 | +1.2万股 | 新买入 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | — | #36 | $30.7万 | 1.2万股 | $0 | 0股 | +1.2万股 | 新买入 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #40 | $25.3万 | 1.0万股 | $24.4万 | 7,750股 | +2,365股+30.52% | 加仓 |
| XTX资本XTX Topco Ltd |
| <0.01% | — | #27 | $24.0万 | 9,608股 | $0 | 0股 | +9,608股 | 新买入 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #37 | $15.8万 | 6,307股 | $19.9万 | 6,307股 | 00.00% | 持仓不变 |
| China Universal Asset Management Co., Ltd. |
| 0.01% | — | #25 | $9.0万 | 3,600股 | $0 | 0股 | +3,600股 | 新买入 |
| 贝莱德BlackRock, Inc. |
| <0.01% | — | #44 | $8.5万 | 3,402股 | $0 | 0股 | +3,402股 | 新买入 |
| Tower Research Capital LLC (TRC) |
| <0.01% | <0.01% | #30 | $1.6万 | 650股 | $4.7万 | 1,496股 | -846股-56.55% | 减仓 |
| 加拿大皇家银行ROYAL BANK OF CANADA |
| <0.01% | — | #42 | $1.3万 | 509股 | $0 | 0股 | +509股 | 新买入 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #43 | $2,825 | 113股 | $284 | 9股 | +104股+1,155.56% | 加仓 |
| 摩根大通JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #45 | $929 | 40股 | $804 | 32股 | +8股+25.00% | 加仓 |
| Quarry LP |
| <0.01% | — | #33 | $800 | 32股 | $0 | 0股 | +32股 | 新买入 |
| Physician Wealth Advisors, Inc. |
| <0.01% | — | #31 | $700 | 28股 | $0 | 0股 | +28股 | 新买入 |
| SBI Securities Co., Ltd. |
| <0.01% | <0.01% | #41 | $100 | 4股 | $126 | 4股 | 00.00% | 持仓不变 |
