| Casdin Capital, LLC |
| 3.66% | 6.18% | #1 | $7,304.2万 | 8,878.4万股 | $8,161.9万 | 8,878.4万股 | 00.00% | 持仓不变 |
| 维京全球投资VIKING GLOBAL INVESTORS LP |
| 0.14% | 0.15% | #9 | $4,825.2万 | 5,865.1万股 | $5,391.8万 | 5,865.1万股 | 00.00% | 持仓不变 |
| MAK CAPITAL ONE LLC |
| 3.32% | 3.55% | #2 | $2,370.5万 | 2,881.4万股 | $2,406.0万 | 2,617.3万股 | +264.1万股+10.09% | 加仓 |
| Long Focus 资本管理Long Focus Capital Management, LLC |
| 0.5% | 0.39% | #7 | $1,933.3万 | 2,350.0万股 | $1,472.3万 | 1,601.6万股 | +748.4万股+46.73% | 加仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #60 | $1,008.4万 | 1,225.3万股 | $1,177.8万 | 1,281.6万股 | -56.3万股-4.39% | 减仓 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #72 | $679.1万 | 825.4万股 | $2,275.8万 | 2,475.6万股 | -1,650.2万股-66.66% | 减仓 |
| Hollow Brook Wealth Management LLC |
| 0.9% | 1.33% | #4 | $452.8万 | 550.3万股 | $519.7万 | 565.3万股 | -15.0万股-2.65% | 减仓 |
| 纽伯格伯曼集团Neuberger Berman Group LLC |
| <0.01% | <0.01% | #29 | $403.9万 | 495.9万股 | $428.1万 | 465.8万股 | +30.1万股+6.46% | 加仓 |
| Qube研究科技Qube Research & Technologies Ltd |
| <0.01% | <0.01% | #25 | $396.6万 | 482.0万股 | $64.8万 | 70.4万股 | +411.6万股+584.33% | 加仓 |
| Royce联营ROYCE & ASSOCIATES LP |
| 0.03% | 0.03% | #15 | $372.3万 | 452.5万股 | $276.3万 | 300.6万股 | +152.0万股+50.57% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #64 | $320.7万 | 389.7万股 | $670.3万 | 728.9万股 | -339.3万股-46.54% | 减仓 |
| Tikvah Management LLC |
| 0.89% | 1.01% | #5 | $292.1万 | 355.1万股 | $326.5万 | 355.1万股 | -94股-0.00% | 减仓 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #39 | $289.0万 | 351.3万股 | $193.2万 | 210.2万股 | +141.1万股+67.11% | 加仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #68 | $233.0万 | 283.2万股 | $826.2万 | 635.5万股 | -352.3万股-55.44% | 减仓 |
| D.E.肖D. E. Shaw & Co., Inc. |
| <0.01% | <0.01% | #37 | $231.8万 | 281.8万股 | $18.3万 | 19.9万股 | +261.9万股+1,315.50% | 加仓 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | — | #63 | $208.0万 | 252.8万股 | $0 | 0股 | +252.8万股 | 新买入 |
| Peapod Lane Capital LLC |
| 1.34% | 1.53% | #3 | $198.4万 | 241.1万股 | $186.2万 | 202.9万股 | +38.3万股+18.88% | 加仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #59 | $195.6万 | 237.7万股 | $116.6万 | 126.9万股 | +110.8万股+87.38% | 加仓 |
| Mink Brook Asset Management LLC |
| 0.8% | — | #6 | $180.3万 | 219.1万股 | $0 | 0股 | +219.1万股 | 新买入 |
| Sone Capital Management, LLC |
| 0.13% | 0.14% | #10 | $175.5万 | 213.4万股 | $162.4万 | 176.7万股 | +36.7万股+20.76% | 加仓 |
| 箭街资本ARROWSTREET CAPITAL, LIMITED PARTNERSHIP |
| <0.01% | — | #46 | $163.8万 | 199.1万股 | $0 | 0股 | +199.1万股 | 新买入 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #53 | $155.5万 | 189.0万股 | $176.2万 | 191.7万股 | -2.8万股-1.44% | 减仓 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #62 | $144.7万 | 175.9万股 | $222.0万 | 241.5万股 | -65.6万股-27.15% | 减仓 |
| Jacobs Levy股票管理JACOBS LEVY EQUITY MANAGEMENT, INC |
| <0.01% | — | #21 | $134.4万 | 163.3万股 | $0 | 0股 | +163.3万股 | 新买入 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #94 | $126.9万 | 154.2万股 | $602.7万 | 655.7万股 | -501.4万股-76.47% | 减仓 |
| AQR资本管理AQR CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #51 | $111.8万 | 135.9万股 | $85.8万 | 93.3万股 | +42.6万股+45.65% | 加仓 |
| Loews集团LOEWS CORP |
| 0.01% | — | #18 | $102.8万 | 125.0万股 | $0 | 0股 | +125.0万股 | 新买入 |
| GSA CAPITAL PARTNERS LLP |
| 0.06% | 0.02% | #11 | $97.7万 | 118.8万股 | $32.5万 | 35.3万股 | +83.4万股+236.01% | 加仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | — | #36 | $81.6万 | 99.2万股 | $0 | 0股 | +99.2万股 | 新买入 |
| STALEY CAPITAL ADVISERS INC |
| 0.03% | 0.03% | #16 | $65.8万 | 80.0万股 | $58.1万 | 63.2万股 | +16.8万股+26.50% | 加仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #77 | $65.1万 | 79.2万股 | $225.6万 | 245.4万股 | -166.3万股-67.75% | 减仓 |
| 英仕曼集团Man Group plc |
| <0.01% | — | #40 | $61.1万 | 74.3万股 | $0 | 0股 | +74.3万股 | 新买入 |
| Point72资产管理Point72 Asset Management, L.P. |
| <0.01% | <0.01% | #47 | $58.2万 | 70.8万股 | $4.1万 | 4.5万股 | +66.3万股+1,483.13% | 加仓 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #101 | $55.5万 | 67.5万股 | $220.0万 | 239.4万股 | -172.0万股-71.82% | 减仓 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #98 | $40.3万 | 49.0万股 | $14.1万 | 15.3万股 | +33.7万股+219.74% | 加仓 |
| Jain GlobalJain Global LLC |
| <0.01% | — | #32 | $38.4万 | 46.7万股 | $0 | 0股 | +46.7万股 | 新买入 |
| 洛克菲勒资本管理Rockefeller Capital Management L.P. |
| <0.01% | <0.01% | #48 | $35.3万 | 42.9万股 | $48.5万 | 52.7万股 | -9.9万股-18.75% | 减仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #90 | $35.1万 | 42.6万股 | $28.0万 | 30.5万股 | +12.1万股+39.61% | 加仓 |
| 三井住友信托集团Sumitomo Mitsui Trust Group, Inc. |
| <0.01% | <0.01% | #61 | $33.9万 | 41.2万股 | $40.7万 | 44.3万股 | -3.0万股-6.89% | 减仓 |
| Amova资产管理Amova Asset Management Americas, Inc. |
| <0.01% | 0.01% | #22 | $33.8万 | 41.2万股 | $40.7万 | 44.3万股 | -3.0万股-6.89% | 减仓 |
| Intellectus Partners, LLC |
| 0.06% | 0.08% | #12 | $33.3万 | 40.5万股 | $37.2万 | 40.5万股 | 00.00% | 持仓不变 |
| HighTower顾问HighTower Advisors, LLC |
| <0.01% | <0.01% | #57 | $29.3万 | 35.6万股 | $5.0万 | 5.4万股 | +30.1万股+552.55% | 加仓 |
| 未来资产环球ETFMIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
| <0.01% | <0.01% | #55 | $27.0万 | 32.9万股 | $28.9万 | 31.4万股 | +1.4万股+4.59% | 加仓 |
| 奥本海默公司OPPENHEIMER & CO INC |
| <0.01% | <0.01% | #28 | $26.9万 | 32.7万股 | $32.3万 | 35.1万股 | -2.4万股-6.92% | 减仓 |
| Marquette Asset Management, LLC |
| 0.03% | — | #13 | $26.8万 | 32.5万股 | $0 | 0股 | +32.5万股 | 新买入 |
| JOHNSON & JOHNSON |
| 0.03% | 0.04% | #14 | $25.7万 | 31.2万股 | $28.7万 | 31.2万股 | 00.00% | 持仓不变 |
| 萨斯奎汉纳组合策略Susquehanna Portfolio Strategies, LLC |
| <0.01% | — | #24 | $24.0万 | 29.2万股 | $0 | 0股 | +29.2万股 | 新买入 |
| XTX资本XTX Topco Ltd |
| <0.01% | 0.01% | #27 | $22.9万 | 27.8万股 | $30.2万 | 32.9万股 | -5.1万股-15.54% | 减仓 |
| SquarepointSquarepoint Ops LLC |
| <0.01% | — | #58 | $22.8万 | 27.7万股 | $0 | 0股 | +27.7万股 | 新买入 |
| 汇丰控股HSBC HOLDINGS PLC |
| <0.01% | — | #74 | $21.9万 | 27.2万股 | $0 | 0股 | +27.2万股 | 新买入 |
