| GILEAD SCIENCES, INC. |
| 8.3% | 5.9% | #1 | $1.37亿 | 497.7万股 | $1.25亿 | 450.5万股 | +47.2万股+10.47% | 加仓 |
| 法伦资本FARALLON CAPITAL MANAGEMENT, L.L.C. |
| 0.2% | 0.19% | #15 | $4,409.4万 | 160.5万股 | $3,406.6万 | 122.8万股 | +37.7万股+30.71% | 加仓 |
| 范式生物资本Paradigm Biocapital Advisors LP |
| 0.8% | 0.38% | #9 | $4,269.7万 | 155.4万股 | $1,846.1万 | 66.5万股 | +88.8万股+133.56% | 加仓 |
| Commodore Capital LP |
| 2.32% | 1.61% | #3 | $3,888.4万 | 141.5万股 | $2,775.0万 | 100.0万股 | +41.5万股+41.50% | 加仓 |
| RA资本管理RA CAPITAL MANAGEMENT, L.P. |
| 0.24% | 0.3% | #13 | $2,804.1万 | 102.0万股 | $2,831.6万 | 102.0万股 | 00.00% | 持仓不变 |
| 木星资产管理Jupiter Topco LLC |
| 0.01% | — | #29 | $2,336.9万 | 84.9万股 | $0 | 0股 | +84.9万股 | 新买入 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #58 | $2,107.2万 | 76.7万股 | $562.6万 | 20.3万股 | +56.4万股+278.22% | 加仓 |
| Parkman Healthcare Partners LLC |
| 2.03% | 1.18% | #5 | $1,981.8万 | 72.1万股 | $1,141.2万 | 41.1万股 | +31.0万股+75.37% | 加仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #56 | $1,536.0万 | 55.9万股 | $1,361.0万 | 49.0万股 | +6.8万股+13.97% | 加仓 |
| Point72资产管理Point72 Asset Management, L.P. |
| 0.01% | 0.01% | #27 | $1,265.7万 | 46.1万股 | $954.9万 | 34.4万股 | +11.6万股+33.85% | 加仓 |
| Seven Fleet Capital Management LP |
| 1.96% | 0.49% | #6 | $1,190.3万 | 43.3万股 | $155.8万 | 5.6万股 | +37.7万股+671.45% | 加仓 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #35 | $821.1万 | 29.9万股 | $648.4万 | 23.4万股 | +6.5万股+27.89% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #49 | $770.8万 | 28.0万股 | $369.2万 | 13.3万股 | +14.7万股+110.89% | 加仓 |
| Schonfeld战略顾问Schonfeld Strategic Advisors LLC |
| 0.02% | 0.02% | #24 | $665.4万 | 24.2万股 | $334.4万 | 12.1万股 | +12.2万股+100.96% | 加仓 |
| 阿默普莱斯金融AMERIPRISE FINANCIAL INC |
| <0.01% | — | #40 | $632.0万 | 23.0万股 | $0 | 0股 | +23.0万股 | 新买入 |
| DV EQUITIES, LLC |
| 0.89% | — | #8 | $622.2万 | 22.6万股 | $0 | 0股 | +22.6万股 | 新买入 |
| 安本标准投资Aberdeen Group plc |
| 0.01% | — | #30 | $569.0万 | 20.7万股 | $0 | 0股 | +20.7万股 | 新买入 |
| Affinity Asset Advisors, LLC |
| 0.24% | — | #14 | $522.1万 | 19.0万股 | $0 | 0股 | +19.0万股 | 新买入 |
| B Group, Inc. |
| 2.27% | 3.61% | #4 | $482.8万 | 17.6万股 | $487.6万 | 17.6万股 | 00.00% | 持仓不变 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #67 | $472.5万 | 17.2万股 | $157.3万 | 5.7万股 | +11.5万股+203.29% | 加仓 |
| STEMPOINT CAPITAL LP |
| 0.67% | 0.95% | #10 | $468.2万 | 17.0万股 | $514.6万 | 18.5万股 | -1.5万股-8.12% | 减仓 |
| Squadron Capital Management LLC |
| 1.36% | — | #7 | $439.7万 | 16.0万股 | $0 | 0股 | +16.0万股 | 新买入 |
| Woodline合伙人Woodline Partners LP |
| 0.01% | — | #28 | $414.3万 | 15.1万股 | $0 | 0股 | +15.1万股 | 新买入 |
| Driehaus资本管理DRIEHAUS CAPITAL MANAGEMENT LLC |
| 0.02% | — | #23 | $412.2万 | 15.0万股 | $0 | 0股 | +15.0万股 | 新买入 |
| Ally Bridge Group (NY) LLC |
| 3.4% | — | #2 | $384.7万 | 14.0万股 | $0 | 0股 | +14.0万股 | 新买入 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #55 | $378.8万 | 13.8万股 | $100.5万 | 3.6万股 | +10.2万股+280.70% | 加仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #50 | $338.1万 | 12.3万股 | $113.8万 | 4.1万股 | +8.2万股+199.97% | 加仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #52 | $314.4万 | 11.4万股 | $70.6万 | 2.5万股 | +8.9万股+349.77% | 加仓 |
| 富兰克林资源FRANKLIN RESOURCES INC |
| <0.01% | — | #46 | $311.1万 | 11.3万股 | $0 | 0股 | +11.3万股 | 新买入 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #69 | $250.5万 | 9.1万股 | $49.2万 | 1.8万股 | +7.3万股+414.32% | 加仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #48 | $203.3万 | 7.4万股 | $198.7万 | 7.2万股 | +2,364股+3.30% | 加仓 |
| HighVista Strategies LLC |
| 0.46% | 0.57% | #11 | $201.7万 | 7.3万股 | $207.4万 | 7.5万股 | -1,330股-1.78% | 减仓 |
| Qube研究科技Qube Research & Technologies Ltd |
| <0.01% | <0.01% | #38 | $141.5万 | 5.1万股 | $192.2万 | 6.9万股 | -1.8万股-25.66% | 减仓 |
| MONIMUS CAPITAL MANAGEMENT, LP |
| 0.3% | 0.37% | #12 | $130.7万 | 4.8万股 | $134.3万 | 4.8万股 | -810股-1.67% | 减仓 |
| Trexquant投资Trexquant Investment LP |
| 0.01% | <0.01% | #31 | $125.5万 | 4.6万股 | $63.1万 | 2.3万股 | +2.3万股+100.79% | 加仓 |
| 摩根大通JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #75 | $125.1万 | 4.6万股 | $143.8万 | 5.4万股 | -7,577股-14.04% | 减仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #76 | $124.3万 | 4.5万股 | $9.0万 | 3,527股 | +4.2万股+1,182.08% | 加仓 |
| GSA CAPITAL PARTNERS LLP |
| 0.07% | 0.08% | #18 | $118.0万 | 4.3万股 | $125.0万 | 4.5万股 | -2,118股-4.70% | 减仓 |
| XTX资本XTX Topco Ltd |
| 0.02% | 0.01% | #26 | $117.9万 | 4.3万股 | $29.9万 | 1.1万股 | +3.2万股+297.94% | 加仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #65 | $114.9万 | 4.2万股 | $1.0万 | 364股 | +4.1万股+11,385.16% | 加仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #37 | $108.4万 | 3.9万股 | $43.4万 | 1.6万股 | +2.4万股+152.00% | 加仓 |
| SquarepointSquarepoint Ops LLC |
| <0.01% | <0.01% | #42 | $94.0万 | 3.4万股 | $66.1万 | 2.4万股 | +1.0万股+43.73% | 加仓 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | — | #72 | $80.0万 | 2.9万股 | $0 | 0股 | +2.9万股 | 新买入 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #78 | $74.2万 | 2.7万股 | $91.4万 | 3.3万股 | -5,949股-18.06% | 减仓 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #57 | $66.5万 | 2.4万股 | $4,135 | 149股 | +2.4万股+16,143.62% | 加仓 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| <0.01% | — | #71 | $66.0万 | 2.4万股 | $0 | 0股 | +2.4万股 | 新买入 |
| Connor Clark & Lunn投资管理Connor, Clark & Lunn Investment Management Ltd. |
| <0.01% | <0.01% | #41 | $65.3万 | 2.4万股 | $60.4万 | 2.2万股 | +2,004股+9.21% | 加仓 |
| Caption管理Caption Management, LLC |
| <0.01% | 0.01% | #34 | $62.7万 | 2.3万股 | $227.1万 | 8.2万股 | -5.9万股-72.11% | 减仓 |
| ADAR1 Capital Management, LLC |
| 0.03% | 0.03% | #22 | $56.2万 | 2.0万股 | $55.4万 | 2.0万股 | +500股+2.51% | 加仓 |
| Palumbo Wealth Management LLC |
| 0.12% | 0.13% | #16 | $54.6万 | 2.0万股 | $54.5万 | 2.0万股 | +222股+1.13% | 加仓 |
