| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #108 | $6,286.8万 | 4,911.6万股 | $7,050.6万 | 4,732.0万股 | +179.6万股+3.80% | 加仓 |
| RA资本管理RA CAPITAL MANAGEMENT, L.P. |
| 0.48% | 1.01% | #10 | $5,479.6万 | 4,281.0万股 | $9,501.9万 | 6,377.1万股 | -2,096.2万股-32.87% | 减仓 |
| Soleus 资本管理Soleus Capital Management, L.P. |
| 1.89% | 2.5% | #2 | $5,479.5万 | 4,280.9万股 | $6,184.8万 | 4,150.9万股 | +130.0万股+3.13% | 加仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #97 | $4,589.7万 | 3,585.7万股 | $4,544.1万 | 3,049.7万股 | +535.9万股+17.57% | 加仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | 0.01% | #64 | $3,782.9万 | 2,955.4万股 | $3,294.5万 | 2,211.1万股 | +744.3万股+33.66% | 加仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #119 | $3,488.0万 | 2,725.0万股 | $3,973.7万 | 2,666.9万股 | +58.1万股+2.18% | 加仓 |
| 清水投资Clearbridge Investments, LLC |
| 0.02% | 0.03% | #38 | $2,515.1万 | 1,964.9万股 | $2,923.4万 | 1,962.0万股 | +2.9万股+0.15% | 加仓 |
| Eversept Partners, LP |
| 1.24% | 1.48% | #3 | $2,395.8万 | 1,871.7万股 | $2,806.4万 | 1,883.5万股 | -11.7万股-0.62% | 减仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #88 | $2,129.1万 | 1,663.3万股 | $1,665.3万 | 1,117.7万股 | +545.7万股+48.82% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #106 | $1,863.5万 | 1,455.6万股 | $2,037.4万 | 1,367.1万股 | +88.5万股+6.47% | 加仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #111 | $1,657.0万 | 1,294.5万股 | $1,465.7万 | 1,069.8万股 | +224.7万股+21.00% | 加仓 |
| Nantahala 资本管理Nantahala Capital Management, LLC |
| 0.52% | 0.62% | #6 | $1,564.8万 | 1,222.5万股 | $1,672.5万 | 1,122.5万股 | +100.0万股+8.91% | 加仓 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #131 | $1,384.0万 | 1,081.3万股 | $695.6万 | 466.9万股 | +614.4万股+131.59% | 加仓 |
| Vivo Capital, LLC |
| 1.01% | 1.07% | #4 | $1,110.0万 | 867.2万股 | $1,292.1万 | 867.2万股 | 00.00% | 持仓不变 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #70 | $1,038.4万 | 811.2万股 | $1,090.9万 | 732.2万股 | +79.1万股+10.80% | 加仓 |
| Kynam Capital Management, LP |
| 0.48% | 0.63% | #8 | $875.0万 | 683.6万股 | $1,018.6万 | 683.6万股 | 00.00% | 持仓不变 |
| 康得利安资管Candriam S.C.A. |
| 0.03% | 0.02% | #24 | $714.7万 | 558.9万股 | $374.8万 | 283.9万股 | +275.0万股+96.84% | 加仓 |
| 富达投资FMR LLC |
| <0.01% | <0.01% | #151 | $704.4万 | 550.3万股 | $983.0万 | 659.7万股 | -109.4万股-16.59% | 减仓 |
| Pale Fire Capital SE |
| 0.48% | 0.64% | #9 | $679.3万 | 530.7万股 | $728.4万 | 488.8万股 | +41.9万股+8.57% | 加仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #117 | $644.1万 | 503.2万股 | $724.5万 | 486.2万股 | +17.0万股+3.50% | 加仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #115 | $626.7万 | 489.6万股 | $550.3万 | 369.3万股 | +120.3万股+32.57% | 加仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| 0.01% | <0.01% | #51 | $586.1万 | 457.9万股 | $268.1万 | 180.0万股 | +277.9万股+154.46% | 加仓 |
| 西格尔·布莱恩特·哈米尔SEGALL BRYANT & HAMILL, LLC |
| 0.07% | 0.1% | #16 | $574.2万 | 448.6万股 | $706.3万 | 474.0万股 | -25.4万股-5.37% | 减仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #67 | $551.4万 | 430.8万股 | $281.5万 | 188.9万股 | +241.9万股+128.00% | 加仓 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #121 | $548.4万 | 428.5万股 | $668.0万 | 448.3万股 | -19.9万股-4.43% | 减仓 |
| 多伦多道明银行TORONTO DOMINION BANK |
| 0.01% | <0.01% | #58 | $542.1万 | 423.5万股 | $19.0万 | 12.8万股 | +410.7万股+3,216.08% | 加仓 |
| Point72资产管理Point72 Asset Management, L.P. |
| 0.01% | 0.04% | #60 | $517.8万 | 404.5万股 | $3,048.1万 | 2,045.7万股 | -1,641.2万股-80.23% | 减仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #103 | $507.3万 | 396.4万股 | $571.4万 | 383.5万股 | +12.8万股+3.35% | 加仓 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #154 | $452.4万 | 353.4万股 | $678.9万 | 455.6万股 | -102.2万股-22.43% | 减仓 |
| DEUTSCHE 银行 AG\DEUTSCHE BANK AG\ |
| <0.01% | <0.01% | #98 | $440.3万 | 344.0万股 | $775.3万 | 520.4万股 | -176.4万股-33.89% | 减仓 |
| Qube研究科技Qube Research & Technologies Ltd |
| <0.01% | <0.01% | #66 | $430.3万 | 336.2万股 | $215.4万 | 144.6万股 | +191.6万股+132.50% | 加仓 |
| PanAgora资产管理PANAGORA ASSET MANAGEMENT INC |
| 0.01% | <0.01% | #42 | $376.3万 | 293.9万股 | $53.8万 | 36.1万股 | +257.9万股+714.61% | 加仓 |
| ExodusPoint资本ExodusPoint Capital Management, LP |
| 0.02% | — | #37 | $323.3万 | 252.6万股 | $0 | 0股 | +252.6万股 | 新买入 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #93 | $309.3万 | 241.6万股 | $63.6万 | 42.7万股 | +199.0万股+466.31% | 加仓 |
| 爱德蒙·罗斯柴尔德控股EDMOND DE ROTHSCHILD HOLDING S.A. |
| 0.04% | 0.05% | #21 | $298.2万 | 233.0万股 | $347.2万 | 233.0万股 | 00.00% | 持仓不变 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #171 | $287.7万 | 224.8万股 | $352.3万 | 236.5万股 | -11.7万股-4.93% | 减仓 |
| NAN FUNG TRINITY (HK) Ltd |
| 0.28% | 0.22% | #12 | $284.6万 | 222.4万股 | $204.7万 | 137.4万股 | +85.0万股+61.88% | 加仓 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| <0.01% | <0.01% | #148 | $207.1万 | 161.8万股 | $229.5万 | 154.0万股 | +7.8万股+5.06% | 加仓 |
| 纽文Nuveen, LLC |
| <0.01% | <0.01% | #140 | $197.9万 | 154.6万股 | $436.8万 | 293.1万股 | -138.5万股-47.25% | 减仓 |
| 世界投资顾问World Investment Advisors |
| 0.03% | 0.02% | #29 | $154.0万 | 103.4万股 | $154.0万 | 103.4万股 | 00.00% | 持仓不变 |
| 摩尔资本管理MOORE CAPITAL MANAGEMENT, LP |
| 0.02% | — | #33 | $152.6万 | 119.2万股 | $0 | 0股 | +119.2万股 | 新买入 |
| 景顺Invesco Ltd. |
| <0.01% | <0.01% | #191 | $150.4万 | 117.5万股 | $194.4万 | 130.4万股 | -12.9万股-9.91% | 减仓 |
| Seven Fleet Capital Management LP |
| 0.22% | 0.2% | #13 | $135.3万 | 105.7万股 | $63.2万 | 42.4万股 | +63.3万股+149.24% | 加仓 |
| Virtus Investment Advisers, LLC |
| 0.3% | 0.26% | #11 | $129.4万 | 101.1万股 | $92.5万 | 62.1万股 | +39.0万股+62.89% | 加仓 |
| 沃利昂资本管理Voleon Capital Management LP |
| 0.02% | <0.01% | #32 | $128.6万 | 100.5万股 | $18.3万 | 12.3万股 | +88.2万股+719.65% | 加仓 |
| Hennion & Walsh Asset Management, Inc. |
| 0.04% | 0.02% | #23 | $128.1万 | 100.1万股 | $59.1万 | 39.7万股 | +60.4万股+152.35% | 加仓 |
| 瑞银资产管理(美洲)UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
| <0.01% | <0.01% | #167 | $125.9万 | 98.4万股 | $189.4万 | 127.1万股 | -28.7万股-22.61% | 减仓 |
| 瑞士央行Swiss National Bank |
| <0.01% | <0.01% | #126 | $123.4万 | 96.4万股 | $141.2万 | 94.8万股 | +1.7万股+1.74% | 加仓 |
| 花旗集团CITIGROUP INC |
| <0.01% | <0.01% | #147 | $105.8万 | 82.6万股 | $94.4万 | 63.4万股 | +19.3万股+30.42% | 加仓 |
| RhumbLine顾问RHUMBLINE ADVISERS |
| <0.01% | <0.01% | #123 | $93.7万 | 73.2万股 | $104.3万 | 70.0万股 | +3.2万股+4.57% | 加仓 |
