| 贝克兄弟顾问BAKER BROS. ADVISORS LP |
| 0.23% | 0.29% | #10 | $4,615.4万 | 1,088.5万股 | $5,050.8万 | 1,088.5万股 | 00.00% | 持仓不变 |
| FCPM III SERVICES B.V. |
| 1.96% | 2.23% | #1 | $1,470.6万 | 346.8万股 | $1,609.4万 | 346.8万股 | 00.00% | 持仓不变 |
| 停战资本ARMISTICE CAPITAL, LLC |
| 0.18% | 0.28% | #12 | $1,440.8万 | 339.8万股 | $1,576.7万 | 339.8万股 | 00.00% | 持仓不变 |
| Long Focus 资本管理Long Focus Capital Management, LLC |
| 0.36% | 0.4% | #7 | $1,403.7万 | 331.1万股 | $1,536.2万 | 331.1万股 | 00.00% | 持仓不变 |
| ACADIAN ASSET MANAGEMENT LLC |
| 0.01% | 0.01% | #27 | $834.4万 | 196.8万股 | $911.1万 | 196.8万股 | 00.00% | 持仓不变 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| 0.01% | 0.01% | #29 | $650.2万 | 153.3万股 | $454.4万 | 97.9万股 | +55.4万股+56.58% | 加仓 |
| GSK plc |
| 1.08% | 1.18% | #3 | $648.5万 | 153.0万股 | $709.7万 | 153.0万股 | 00.00% | 持仓不变 |
| 普信集团PRICE T ROWE ASSOCIATES INC /MD/ |
| <0.01% | <0.01% | #58 | $382.5万 | 90.2万股 | $477.2万 | 102.8万股 | -12.6万股-12.26% | 减仓 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| <0.01% | <0.01% | #39 | $338.3万 | 79.8万股 | $175.1万 | 37.7万股 | +42.1万股+111.47% | 加仓 |
| Qube研究科技Qube Research & Technologies Ltd |
| <0.01% | <0.01% | #37 | $328.8万 | 77.6万股 | $143.2万 | 30.9万股 | +46.7万股+151.30% | 加仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #72 | $282.9万 | 66.7万股 | $636.8万 | 82.3万股 | -15.5万股-18.89% | 减仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #61 | $266.2万 | 62.8万股 | $190.6万 | 41.1万股 | +21.7万股+52.85% | 加仓 |
| 施罗德投资管理SCHRODER INVESTMENT MANAGEMENT GROUP |
| <0.01% | <0.01% | #41 | $255.6万 | 61.6万股 | $267.3万 | 61.6万股 | 00.00% | 持仓不变 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #47 | $234.9万 | 55.4万股 | $131.8万 | 28.4万股 | +27.0万股+95.07% | 加仓 |
| Peapod Lane Capital LLC |
| 1.54% | 0.45% | #2 | $228.1万 | 53.8万股 | $55.0万 | 12.1万股 | +41.7万股+344.22% | 加仓 |
| DIADEMA PARTNERS LP |
| 0.24% | 0.38% | #9 | $196.2万 | 46.3万股 | $221.1万 | 47.6万股 | -1.4万股-2.88% | 减仓 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #70 | $192.8万 | 45.5万股 | $140.6万 | 30.3万股 | +15.2万股+50.08% | 加仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #44 | $184.3万 | 43.5万股 | $76.5万 | 16.5万股 | +27.0万股+163.70% | 加仓 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #73 | $149.4万 | 35.2万股 | $137.7万 | 29.7万股 | +5.6万股+18.72% | 加仓 |
| Birchview Capital, LP |
| 0.6% | 1.22% | #6 | $133.0万 | 31.4万股 | $215.1万 | 46.4万股 | -15.0万股-32.35% | 减仓 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #84 | $118.9万 | 28.0万股 | $129.5万 | 27.9万股 | +1,394股+0.50% | 加仓 |
| 摩尔资本管理MOORE CAPITAL MANAGEMENT, LP |
| 0.02% | 0.03% | #24 | $116.6万 | 27.5万股 | $127.6万 | 27.5万股 | 00.00% | 持仓不变 |
| Rangeley Capital, LLC |
| 1.03% | 1.05% | #4 | $107.5万 | 25.4万股 | $107.8万 | 23.2万股 | +2.1万股+9.14% | 加仓 |
| FLAX POND CAPITAL, LLC |
| 0.69% | 0.66% | #5 | $91.0万 | 19.6万股 | $81.7万 | 17.6万股 | +2.0万股+11.35% | 加仓 |
| Palo Alto Investors LP |
| 0.13% | 0.14% | #14 | $85.6万 | 20.2万股 | $93.7万 | 20.2万股 | 00.00% | 持仓不变 |
| 雕塑家资本Sculptor Capital LP |
| 0.01% | — | #32 | $83.9万 | 19.8万股 | $0 | 0股 | +19.8万股 | 新买入 |
| Eversept Partners, LP |
| 0.04% | 0.05% | #19 | $80.9万 | 19.1万股 | $88.5万 | 19.1万股 | 00.00% | 持仓不变 |
| 巅峰联合PINNACLE ASSOCIATES LTD |
| 0.01% | 0.01% | #30 | $80.6万 | 19.0万股 | $86.0万 | 18.5万股 | +4,580股+2.47% | 加仓 |
| 跳跃金融Jump Financial, LLC |
| 0.01% | <0.01% | #34 | $70.9万 | 16.7万股 | $24.4万 | 5.3万股 | +11.5万股+218.02% | 加仓 |
| Point72资产管理Point72 Asset Management, L.P. |
| <0.01% | <0.01% | #50 | $63.6万 | 15.0万股 | $60.5万 | 13.0万股 | +2.0万股+14.96% | 加仓 |
| 宏利人寿MANUFACTURERS LIFE INSURANCE COMPANY, THE |
| <0.01% | <0.01% | #56 | $54.2万 | 12.8万股 | $59.3万 | 12.8万股 | 00.00% | 持仓不变 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #82 | $51.4万 | 12.1万股 | $51.1万 | 11.0万股 | +1.1万股+10.11% | 加仓 |
| Persistent Asset Partners Ltd |
| 0.15% | 0.21% | #13 | $49.7万 | 11.7万股 | $55.9万 | 12.0万股 | -3,183股-2.64% | 减仓 |
| XTX资本XTX Topco Ltd |
| 0.01% | 0.01% | #33 | $46.6万 | 11.0万股 | $49.4万 | 10.6万股 | +3,409股+3.20% | 加仓 |
| 正交资本Quadrature Capital Ltd |
| <0.01% | — | #36 | $44.1万 | 10.4万股 | $0 | 0股 | +10.4万股 | 新买入 |
| 道明资产管理TD ASSET MANAGEMENT INC |
| <0.01% | <0.01% | #59 | $39.0万 | 9.2万股 | $42.7万 | 9.2万股 | 00.00% | 持仓不变 |
| Virtus Investment Advisers, LLC |
| 0.08% | 0.05% | #17 | $34.3万 | 8.1万股 | $17.0万 | 3.7万股 | +4.4万股+120.73% | 加仓 |
| NANO CAP NEW MILLENNIUM GROWTH FUND L P |
| 0.26% | — | #8 | $33.9万 | 8.0万股 | $0 | 0股 | +8.0万股 | 新买入 |
| EntryPoint Capital, LLC |
| 0.08% | 0.09% | #16 | $33.0万 | 7.8万股 | $29.7万 | 6.4万股 | +1.4万股+21.65% | 加仓 |
| Marquette Asset Management, LLC |
| 0.04% | — | #21 | $30.9万 | 7.3万股 | $0 | 0股 | +7.3万股 | 新买入 |
| HRT金融HRT FINANCIAL LP |
| <0.01% | <0.01% | #54 | $28.1万 | 6.6万股 | $21.3万 | 4.6万股 | +2.0万股+44.26% | 加仓 |
| DAFNA Capital Management LLC |
| 0.05% | 0.07% | #18 | $27.3万 | 6.4万股 | $29.9万 | 6.4万股 | 00.00% | 持仓不变 |
| 田纳西州财政部State of Tennessee, Department of Treasury |
| <0.01% | <0.01% | #49 | $25.9万 | 6.1万股 | $28.4万 | 6.1万股 | 00.00% | 持仓不变 |
| SEI投资SEI INVESTMENTS CO |
| <0.01% | <0.01% | #67 | $22.4万 | 5.3万股 | $24.5万 | 5.3万股 | 00.00% | 持仓不变 |
| ALPS顾问ALPS ADVISORS INC |
| <0.01% | <0.01% | #46 | $21.7万 | 5.1万股 | $18.9万 | 4.1万股 | +1.0万股+25.76% | 加仓 |
| Verdad Advisers, LP |
| 0.21% | — | #11 | $21.7万 | 5.1万股 | $0 | 0股 | +5.1万股 | 新买入 |
| ADAR1 Capital Management, LLC |
| 0.01% | 0.02% | #28 | $21.5万 | 5.1万股 | $33.1万 | 7.1万股 | -2.1万股-28.98% | 减仓 |
| Simplex交易SIMPLEX TRADING, LLC |
| <0.01% | <0.01% | #74 | $14.9万 | 3.5万股 | $85.4万 | 18.4万股 | -14.9万股-80.85% | 减仓 |
| WOODSTOCK CORP |
| 0.01% | 0.01% | #26 | $13.5万 | 2.9万股 | $13.5万 | 2.9万股 | 00.00% | 持仓不变 |
| Trexquant投资Trexquant Investment LP |
| <0.01% | — | #48 | $13.2万 | 3.1万股 | $0 | 0股 | +3.1万股 | 新买入 |
