| Deerfield管理DEERFIELD MANAGEMENT COMPANY, L.P. |
| 1.13% | 1.89% | #4 | $1.09亿 | 3,560.7万股 | $1.60亿 | 3,560.7万股 | 00.00% | 持仓不变 |
| Blue Owl Capital Holdings LP |
| 4.07% | 8.61% | #1 | $2,794.8万 | 916.3万股 | $3,204.0万 | 712.0万股 | +204.3万股+28.70% | 加仓 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #84 | $1,731.8万 | 567.8万股 | $1,688.5万 | 375.2万股 | +192.6万股+51.33% | 加仓 |
| Defilade Capital Management, L.P. |
| 1.5% | — | #2 | $1,119.4万 | 367.0万股 | $0 | 0股 | +367.0万股 | 新买入 |
| Driehaus资本管理DRIEHAUS CAPITAL MANAGEMENT LLC |
| 0.06% | 0.1% | #11 | $964.8万 | 316.3万股 | $1,320.5万 | 293.4万股 | +22.9万股+7.80% | 加仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #93 | $907.3万 | 297.5万股 | $1,289.9万 | 286.6万股 | +10.9万股+3.79% | 加仓 |
| RTW投资RTW INVESTMENTS, LP |
| 0.07% | 0.07% | #9 | $782.6万 | 256.6万股 | $675.0万 | 150.0万股 | +106.6万股+71.07% | 加仓 |
| AQR资本管理AQR CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #37 | $723.3万 | 237.1万股 | $367.9万 | 81.8万股 | +155.4万股+190.08% | 加仓 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| <0.01% | <0.01% | #27 | $613.8万 | 201.2万股 | $420.1万 | 93.3万股 | +107.9万股+115.59% | 加仓 |
| DAFNA Capital Management LLC |
| 1.17% | 2.08% | #3 | $612.5万 | 200.8万股 | $913.1万 | 202.9万股 | -2.1万股-1.03% | 减仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #62 | $562.1万 | 184.3万股 | $743.2万 | 165.2万股 | +19.1万股+11.58% | 加仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #57 | $523.7万 | 171.7万股 | $270.1万 | 60.0万股 | +111.7万股+186.09% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #82 | $512.2万 | 167.9万股 | $499.1万 | 110.9万股 | +57.0万股+51.43% | 加仓 |
| Qube研究科技Qube Research & Technologies Ltd |
| <0.01% | <0.01% | #29 | $500.5万 | 164.1万股 | $381.4万 | 84.8万股 | +79.3万股+93.60% | 加仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #103 | $430.6万 | 141.2万股 | $410.1万 | 91.1万股 | +50.0万股+54.92% | 加仓 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #94 | $428.0万 | 140.3万股 | $183.0万 | 40.7万股 | +99.7万股+245.13% | 加仓 |
| Woodline合伙人Woodline Partners LP |
| 0.01% | 0.02% | #20 | $427.3万 | 140.1万股 | $630.4万 | 140.1万股 | 00.00% | 持仓不变 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | 0.01% | #46 | $406.6万 | 133.3万股 | $1,631.4万 | 362.5万股 | -229.2万股-63.23% | 减仓 |
| 维度基金顾问DIMENSIONAL FUND ADVISORS LP |
| <0.01% | <0.01% | #60 | $293.2万 | 96.1万股 | $359.2万 | 79.8万股 | +16.3万股+20.37% | 加仓 |
| 富达投资FMR LLC |
| <0.01% | <0.01% | #104 | $285.9万 | 93.7万股 | $28.6万 | 6.4万股 | +87.4万股+1,374.54% | 加仓 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #88 | $284.3万 | 93.2万股 | $219.4万 | 48.8万股 | +44.5万股+91.16% | 加仓 |
| SPHERA FUNDS MANAGEMENT LTD. |
| 0.37% | — | #6 | $282.4万 | 92.6万股 | $0 | 0股 | +92.6万股 | 新买入 |
| 纽文Nuveen, LLC |
| <0.01% | <0.01% | #56 | $273.1万 | 89.5万股 | $303.7万 | 67.5万股 | +22.0万股+32.65% | 加仓 |
| Alyeska投资集团Alyeska Investment Group, L.P. |
| <0.01% | 0.01% | #28 | $188.2万 | 61.7万股 | $277.7万 | 61.7万股 | 00.00% | 持仓不变 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #92 | $167.8万 | 55.0万股 | $169.4万 | 37.7万股 | +17.4万股+46.15% | 加仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #80 | $136.7万 | 44.8万股 | $130.3万 | 29.0万股 | +15.9万股+54.74% | 加仓 |
| Fi3 FINANCIAL ADVISORS, LLC |
| 0.3% | 0.04% | #7 | $126.4万 | 2,915股 | $13.3万 | 2.9万股 | -2.7万股-90.12% | 减仓 |
| 洛杉矶资本管理LOS ANGELES CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #31 | $121.9万 | 40.0万股 | $8.1万 | 1.8万股 | +38.2万股+2,116.97% | 加仓 |
| Hennion & Walsh Asset Management, Inc. |
| 0.03% | — | #15 | $121.0万 | 39.7万股 | $0 | 0股 | +39.7万股 | 新买入 |
| SummitTX 资本SummitTX Capital, L.P. |
| 0.03% | 0.05% | #17 | $107.4万 | 35.2万股 | $170.9万 | 38.0万股 | -2.7万股-7.24% | 减仓 |
| 摩根大通JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #125 | $105.0万 | 32.8万股 | $143.0万 | 33.2万股 | -3,803股-1.15% | 减仓 |
| Gem Investment Advisors, LLC |
| 0.6% | 1.01% | #5 | $97.5万 | 32.0万股 | $107.0万 | 28.1万股 | +3.9万股+13.76% | 加仓 |
| Burkehill Global 管理Burkehill Global Management, LP |
| 0.03% | 0.07% | #16 | $91.5万 | 30.0万股 | $135.0万 | 30.0万股 | 00.00% | 持仓不变 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | 0.01% | #47 | $90.7万 | 29.7万股 | $333.0万 | 74.0万股 | -44.2万股-59.80% | 减仓 |
| ADAR1 Capital Management, LLC |
| 0.04% | 0.01% | #13 | $83.2万 | 27.3万股 | $23.7万 | 5.3万股 | +22.0万股+417.10% | 加仓 |
| Cerity合伙人Cerity Partners LLC |
| <0.01% | <0.01% | #50 | $82.8万 | 27.2万股 | $111.6万 | 24.8万股 | +2.4万股+9.55% | 加仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #61 | $72.0万 | 23.6万股 | $214.0万 | 47.6万股 | -23.9万股-50.35% | 减仓 |
| Seven Fleet Capital Management LP |
| 0.12% | 0.37% | #8 | $70.4万 | 23.1万股 | $115.5万 | 25.7万股 | -2.6万股-10.00% | 减仓 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #117 | $63.1万 | 20.7万股 | $65.4万 | 14.5万股 | +6.2万股+42.40% | 加仓 |
| IEQ资本IEQ CAPITAL, LLC |
| <0.01% | <0.01% | #35 | $62.0万 | 20.3万股 | $51.3万 | 11.4万股 | +8.9万股+78.33% | 加仓 |
| Caption管理Caption Management, LLC |
| <0.01% | 0.02% | #36 | $58.9万 | 19.3万股 | $359.7万 | 79.9万股 | -60.6万股-75.85% | 减仓 |
| Soleus 资本管理Soleus Capital Management, L.P. |
| 0.02% | 0.19% | #19 | $57.4万 | 18.8万股 | $480.1万 | 106.7万股 | -87.9万股-82.37% | 减仓 |
| Jacobs Levy股票管理JACOBS LEVY EQUITY MANAGEMENT, INC |
| <0.01% | <0.01% | #43 | $52.0万 | 17.1万股 | $76.1万 | 16.9万股 | +1,431股+0.85% | 加仓 |
| 萨斯奎汉纳组合策略Susquehanna Portfolio Strategies, LLC |
| 0.01% | — | #24 | $50.4万 | 16.5万股 | $0 | 0股 | +16.5万股 | 新买入 |
| 联博ALLIANCEBERNSTEIN L.P. |
| <0.01% | <0.01% | #98 | $48.7万 | 10.8万股 | $28.4万 | 7.5万股 | +3.4万股+45.20% | 加仓 |
| DIADEMA PARTNERS LP |
| 0.06% | 0.13% | #12 | $44.7万 | 14.7万股 | $75.0万 | 16.7万股 | -2.0万股-12.00% | 减仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #127 | $44.0万 | 14.4万股 | $13.4万 | 3.0万股 | +11.5万股+385.96% | 加仓 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| <0.01% | <0.01% | #120 | $42.3万 | 13.9万股 | $48.3万 | 10.7万股 | +3.2万股+29.35% | 加仓 |
| 威斯康星州投资委员会STATE OF WISCONSIN INVESTMENT BOARD |
| <0.01% | <0.01% | #53 | $42.1万 | 13.8万股 | $13.0万 | 2.9万股 | +10.9万股+379.91% | 加仓 |
| 跳跃金融Jump Financial, LLC |
| <0.01% | 0.02% | #33 | $41.4万 | 13.6万股 | $134.9万 | 30.0万股 | -16.4万股-54.75% | 减仓 |
