| HRTG GPE, LLC |
| 16.26% | — | #1 | $4.03亿 | 1,691.7万股 | $0 | 0股 | +1,691.7万股 | 新买入 |
| 富达投资FMR LLC |
| 0.01% | — | #27 | $2.12亿 | 890.9万股 | $0 | 0股 | +890.9万股 | 新买入 |
| 洞察顾问PERCEPTIVE ADVISORS LLC |
| 2.94% | — | #2 | $1.96亿 | 820.1万股 | $0 | 0股 | +820.1万股 | 新买入 |
| 普信投资管理T. Rowe Price Investment Management, Inc. |
| 0.07% | — | #16 | $1.00亿 | 420.7万股 | $0 | 0股 | +420.7万股 | 新买入 |
| 资本研究全球投资者Capital Research Global Investors |
| 0.01% | — | #25 | $8,583.5万 | 359.9万股 | $0 | 0股 | +359.9万股 | 新买入 |
| 摩根大通JPMORGAN CHASE & CO |
| <0.01% | — | #36 | $4,638.0万 | 179.1万股 | $0 | 0股 | +179.1万股 | 新买入 |
| 联博ALLIANCEBERNSTEIN L.P. |
| 0.01% | — | #24 | $3,660.6万 | 153.5万股 | $0 | 0股 | +153.5万股 | 新买入 |
| Liberty Mutual Group Asset Management Inc. |
| 2.49% | — | #3 | $2,853.4万 | 119.6万股 | $0 | 0股 | +119.6万股 | 新买入 |
| 詹尼森联营JENNISON ASSOCIATES LLC |
| 0.01% | — | #23 | $2,155.0万 | 90.4万股 | $0 | 0股 | +90.4万股 | 新买入 |
| 范式生物资本Paradigm Biocapital Advisors LP |
| 0.4% | — | #6 | $2,146.5万 | 90.0万股 | $0 | 0股 | +90.0万股 | 新买入 |
| 木星资产管理Jupiter Topco LLC |
| 0.01% | — | #28 | $1,771.5万 | 75.0万股 | $0 | 0股 | +75.0万股 | 新买入 |
| 普信集团PRICE T ROWE ASSOCIATES INC /MD/ |
| <0.01% | — | #40 | $1,571.2万 | 65.9万股 | $0 | 0股 | +65.9万股 | 新买入 |
| MFS马萨诸塞金融服务MASSACHUSETTS FINANCIAL SERVICES CO /MA/ |
| 0.01% | — | #31 | $1,550.3万 | 65.0万股 | $0 | 0股 | +65.0万股 | 新买入 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | — | #42 | $1,538.3万 | 64.5万股 | $0 | 0股 | +64.5万股 | 新买入 |
| 深轨资本Deep Track Capital, LP |
| 0.21% | — | #10 | $1,431.0万 | 60.0万股 | $0 | 0股 | +60.0万股 | 新买入 |
| Woodline合伙人Woodline Partners LP |
| 0.03% | — | #19 | $987.3万 | 41.4万股 | $0 | 0股 | +41.4万股 | 新买入 |
| 富兰克林资源FRANKLIN RESOURCES INC |
| <0.01% | — | #37 | $954.1万 | 40.0万股 | $0 | 0股 | +40.0万股 | 新买入 |
| 蒙塔诺瓦资本MONTANOVA CAPITAL, LLC |
| 0.17% | — | #14 | $954.0万 | 40.0万股 | $0 | 0股 | +40.0万股 | 新买入 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| <0.01% | — | #41 | $901.0万 | 37.8万股 | $0 | 0股 | +37.8万股 | 新买入 |
| Catalio Capital Management, LP |
| 1.4% | — | #5 | $745.3万 | 31.3万股 | $0 | 0股 | +31.3万股 | 新买入 |
| 信安金融集团PRINCIPAL FINANCIAL GROUP INC |
| <0.01% | — | #34 | $715.5万 | 30.0万股 | $0 | 0股 | +30.0万股 | 新买入 |
| 暮色资产管理EVENTIDE ASSET MANAGEMENT, LLC |
| 0.1% | — | #15 | $715.5万 | 30.0万股 | $0 | 0股 | +30.0万股 | 新买入 |
| BRAIDWELL LP |
| 0.26% | — | #8 | $715.5万 | 30.0万股 | $0 | 0股 | +30.0万股 | 新买入 |
| 瑞银集团UBS Group AG |
| <0.01% | — | #48 | $638.6万 | 26.8万股 | $0 | 0股 | +26.8万股 | 新买入 |
| PEREGRINE 资本管理PEREGRINE CAPITAL MANAGEMENT LLC |
| 0.18% | — | #13 | $548.0万 | 23.0万股 | $0 | 0股 | +23.0万股 | 新买入 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | — | #39 | $532.0万 | 22.3万股 | $0 | 0股 | +22.3万股 | 新买入 |
| Integral Health 资产管理Integral Health Asset Management, LLC |
| 0.19% | — | #12 | $477.0万 | 20.0万股 | $0 | 0股 | +20.0万股 | 新买入 |
| SEVEN GRAND MANAGERS, LLC |
| 0.19% | — | #11 | $477.0万 | 20.0万股 | $0 | 0股 | +20.0万股 | 新买入 |
| Driehaus资本管理DRIEHAUS CAPITAL MANAGEMENT LLC |
| 0.03% | — | #20 | $476.1万 | 20.0万股 | $0 | 0股 | +20.0万股 | 新买入 |
| HRT金融HRT FINANCIAL LP |
| 0.01% | — | #30 | $372.6万 | 15.6万股 | $0 | 0股 | +15.6万股 | 新买入 |
| 阿默普莱斯金融AMERIPRISE FINANCIAL INC |
| <0.01% | — | #49 | $356.5万 | 14.9万股 | $0 | 0股 | +14.9万股 | 新买入 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | — | #62 | $312.0万 | 13.1万股 | $0 | 0股 | +13.1万股 | 新买入 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | — | #52 | $286.2万 | 12.0万股 | $0 | 0股 | +12.0万股 | 新买入 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | — | #56 | $262.0万 | 11.0万股 | $0 | 0股 | +11.0万股 | 新买入 |
| 雷蒙德詹姆斯金融RAYMOND JAMES FINANCIAL INC |
| <0.01% | — | #50 | $244.5万 | 10.3万股 | $0 | 0股 | +10.3万股 | 新买入 |
| 野村资产管理国际NOMURA ASSET MANAGEMENT INTERNATIONAL INC. |
| <0.01% | — | #35 | $177.0万 | 7.4万股 | $0 | 0股 | +7.4万股 | 新买入 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| <0.01% | — | #43 | $159.4万 | 6.7万股 | $0 | 0股 | +6.7万股 | 新买入 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | — | #60 | $156.0万 | 6.5万股 | $0 | 0股 | +6.5万股 | 新买入 |
| 道明资产管理TD ASSET MANAGEMENT INC |
| <0.01% | — | #45 | $133.1万 | 5.6万股 | $0 | 0股 | +5.6万股 | 新买入 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| <0.01% | — | #61 | $128.3万 | 5.4万股 | $0 | 0股 | +5.4万股 | 新买入 |
| Casdin Capital, LLC |
| 0.06% | — | #17 | $119.3万 | 5.0万股 | $0 | 0股 | +5.0万股 | 新买入 |
| 吉萨洛资本管理Ghisallo Capital Management LLC |
| 0.01% | — | #29 | $119.3万 | 5.0万股 | $0 | 0股 | +5.0万股 | 新买入 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | — | #63 | $106.1万 | 4.4万股 | $0 | 0股 | +4.4万股 | 新买入 |
| Monashee Investment Management LLC |
| 1.71% | — | #4 | $101.8万 | 4.3万股 | $0 | 0股 | +4.3万股 | 新买入 |
| SEI投资SEI INVESTMENTS CO |
| <0.01% | — | #47 | $95.7万 | 4.0万股 | $0 | 0股 | +4.0万股 | 新买入 |
| Shay Capital LLC |
| 0.06% | — | #18 | $91.8万 | 3.9万股 | $0 | 0股 | +3.9万股 | 新买入 |
| Alyeska投资集团Alyeska Investment Group, L.P. |
| <0.01% | — | #38 | $71.6万 | 3.0万股 | $0 | 0股 | +3.0万股 | 新买入 |
| Burkehill Global 管理Burkehill Global Management, LP |
| 0.03% | — | #21 | $71.6万 | 3.0万股 | $0 | 0股 | +3.0万股 | 新买入 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | — | #59 | $47.2万 | 2.0万股 | $0 | 0股 | +2.0万股 | 新买入 |
| 哈德逊湾资本管理Hudson Bay Capital Management LP |
| <0.01% | — | #44 | $45.2万 | 1.9万股 | $0 | 0股 | +1.9万股 | 新买入 |
