| Bratton Capital Management, L.P. |
| 100% | 100% | #1 | $4,081.4万 | 981.1万股 | $4,071.5万 | 981.1万股 | 00.00% | 持仓不变 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #97 | $3,356.9万 | 806.9万股 | $3,116.3万 | 750.9万股 | +56.0万股+7.46% | 加仓 |
| RTW投资RTW INVESTMENTS, LP |
| 0.26% | 0.31% | #10 | $3,089.4万 | 742.6万股 | $3,082.0万 | 742.6万股 | 00.00% | 持仓不变 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | — | #104 | $1,907.2万 | 458.5万股 | $0 | 0股 | +458.5万股 | 新买入 |
| Federated HermesFEDERATED HERMES, INC. |
| 0.02% | 0.02% | #24 | $1,294.8万 | 311.3万股 | $1,220.2万 | 294.0万股 | +17.2万股+5.86% | 加仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #109 | $1,218.1万 | 292.8万股 | $1,056.7万 | 254.6万股 | +38.2万股+15.00% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #94 | $1,091.4万 | 262.3万股 | $999.6万 | 240.8万股 | +21.5万股+8.92% | 加仓 |
| Samsara BioCapital, LLC |
| 0.85% | 1.01% | #5 | $1,040.0万 | 250.0万股 | $1,037.5万 | 250.0万股 | 00.00% | 持仓不变 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #101 | $694.1万 | 166.8万股 | $998.1万 | 240.5万股 | -73.7万股-30.63% | 减仓 |
| Sio Capital Management, LLC |
| 1.02% | 1.14% | #4 | $618.2万 | 148.6万股 | $798.0万 | 192.3万股 | -43.7万股-22.71% | 减仓 |
| Propel Bio Management, LLC |
| 3.14% | 1.86% | #2 | $600.0万 | 144.2万股 | $295.1万 | 71.1万股 | +73.1万股+102.87% | 加仓 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #100 | $577.2万 | 138.8万股 | $670.4万 | 161.5万股 | -22.8万股-14.11% | 减仓 |
| Wasatch顾问WASATCH ADVISORS LP |
| 0.04% | 0.02% | #17 | $576.5万 | 138.6万股 | $364.5万 | 87.8万股 | +50.8万股+57.78% | 加仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #48 | $533.0万 | 128.1万股 | $472.9万 | 113.9万股 | +14.2万股+12.45% | 加仓 |
| 纽文Nuveen, LLC |
| <0.01% | <0.01% | #75 | $505.5万 | 121.5万股 | $105.2万 | 25.3万股 | +96.2万股+379.44% | 加仓 |
| Janney Montgomery Scott LLC |
| 0.01% | 0.01% | #30 | $460.2万 | 110.6万股 | $452.0万 | 108.9万股 | +1.7万股+1.57% | 加仓 |
| 富国银行WELLS FARGO & COMPANY/MN |
| <0.01% | <0.01% | #89 | $453.0万 | 108.9万股 | $429.4万 | 103.5万股 | +5.4万股+5.26% | 加仓 |
| Commonwealth股权服务COMMONWEALTH EQUITY SERVICES, LLC |
| 0.01% | 0.01% | #38 | $435.2万 | 104.6万股 | $449.3万 | 108.3万股 | -3.7万股-3.37% | 减仓 |
| 巴克莱BARCLAYS PLC |
| <0.01% | <0.01% | #86 | $414.6万 | 99.7万股 | $331.7万 | 79.9万股 | +19.8万股+24.71% | 加仓 |
| Blue Owl Capital Holdings LP |
| 0.57% | 1.5% | #7 | $392.3万 | 94.3万股 | $559.4万 | 134.8万股 | -40.5万股-30.05% | 减仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #105 | $345.8万 | 83.1万股 | $304.0万 | 73.3万股 | +9.9万股+13.47% | 加仓 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #71 | $330.6万 | 79.5万股 | $335.7万 | 80.9万股 | -1.4万股-1.77% | 减仓 |
| Balyasny资产管理BALYASNY ASSET MANAGEMENT L.P. |
| <0.01% | 0.02% | #47 | $309.7万 | 74.5万股 | $1,203.7万 | 290.1万股 | -215.6万股-74.33% | 减仓 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | — | #138 | $305.4万 | 73.4万股 | $0 | 0股 | +73.4万股 | 新买入 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #111 | $295.7万 | 71.1万股 | $423.1万 | 102.0万股 | -30.9万股-30.27% | 减仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #136 | $274.0万 | 65.9万股 | $788.3万 | 141.0万股 | -75.1万股-53.29% | 减仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | — | #92 | $270.9万 | 65.1万股 | $0 | 0股 | +65.1万股 | 新买入 |
| DAFNA Capital Management LLC |
| 0.51% | 0.35% | #8 | $268.7万 | 64.6万股 | $152.9万 | 36.8万股 | +27.8万股+75.32% | 加仓 |
| Everstar Asset Management, LLC |
| 1.05% | 1.22% | #3 | $254.6万 | 61.2万股 | $229.6万 | 55.3万股 | +5.9万股+10.62% | 加仓 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #134 | $200.6万 | 48.2万股 | $463.0万 | 111.6万股 | -63.3万股-56.77% | 减仓 |
| AWM Investment Company, Inc. |
| 0.17% | 0.12% | #14 | $197.8万 | 47.5万股 | $112.2万 | 27.0万股 | +20.5万股+75.81% | 加仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #133 | $194.9万 | 46.9万股 | $193.7万 | 46.7万股 | +1,802股+0.39% | 加仓 |
| 布雷克布里奇资本Bracebridge Capital, LLC |
| 0.37% | 0.18% | #9 | $191.0万 | 45.9万股 | $190.6万 | 45.9万股 | 00.00% | 持仓不变 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #122 | $190.7万 | 45.8万股 | $192.6万 | 46.4万股 | -5,793股-1.25% | 减仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | — | #64 | $173.2万 | 41.6万股 | $0 | 0股 | +41.6万股 | 新买入 |
| Stifel金融STIFEL FINANCIAL CORP |
| <0.01% | <0.01% | #74 | $150.6万 | 36.2万股 | $149.4万 | 36.0万股 | +2,000股+0.56% | 加仓 |
| 英仕曼集团Man Group plc |
| <0.01% | — | #65 | $146.3万 | 35.2万股 | $0 | 0股 | +35.2万股 | 新买入 |
| HRT金融HRT FINANCIAL LP |
| <0.01% | — | #61 | $143.4万 | 34.5万股 | $0 | 0股 | +34.5万股 | 新买入 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #132 | $127.5万 | 30.6万股 | $111.0万 | 26.7万股 | +3.9万股+14.57% | 加仓 |
| 惠灵顿管理集团WELLINGTON MANAGEMENT GROUP LLP |
| <0.01% | <0.01% | #126 | $125.5万 | 30.2万股 | $120.4万 | 29.0万股 | +1.2万股+3.99% | 加仓 |
| Group One交易GROUP ONE TRADING LLC |
| <0.01% | 0.01% | #70 | $125.0万 | 30.0万股 | $273.8万 | 66.0万股 | -35.9万股-54.47% | 减仓 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| <0.01% | <0.01% | #81 | $118.8万 | 28.6万股 | $7.6万 | 1.8万股 | +26.7万股+1,459.70% | 加仓 |
| Walleye资本Walleye Capital LLC |
| <0.01% | 0.01% | #44 | $117.5万 | 28.3万股 | $242.8万 | 58.5万股 | -30.2万股-51.70% | 减仓 |
| 简化资产管理Simplify Asset Management Inc. |
| 0.02% | 0.01% | #25 | $115.9万 | 27.9万股 | $97.2万 | 23.4万股 | +4.4万股+18.97% | 加仓 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| <0.01% | <0.01% | #129 | $114.6万 | 27.6万股 | $105.9万 | 25.5万股 | +2.0万股+7.98% | 加仓 |
| 罗素投资集团Russell Investments Group, Ltd. |
| <0.01% | <0.01% | #84 | $108.4万 | 26.0万股 | $93.9万 | 22.6万股 | +3.4万股+15.17% | 加仓 |
| Rosalind Advisors, Inc. |
| 0.25% | 0.42% | #11 | $104.0万 | 25.0万股 | $103.8万 | 25.0万股 | 00.00% | 持仓不变 |
| Latash Investments, LLC |
| 0.74% | 0.78% | #6 | $101.1万 | 24.3万股 | $100.9万 | 24.3万股 | 00.00% | 持仓不变 |
| 哈德逊湾资本管理Hudson Bay Capital Management LP |
| <0.01% | <0.01% | #60 | $97.3万 | 23.4万股 | $97.1万 | 23.4万股 | 00.00% | 持仓不变 |
| Simplex交易SIMPLEX TRADING, LLC |
| <0.01% | <0.01% | #93 | $95.8万 | 23.0万股 | $78.6万 | 18.9万股 | +4.1万股+21.54% | 加仓 |
