| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #87 | $6,323.2万 | 760.9万股 | $7,205.4万 | 679.8万股 | +81.2万股+11.94% | 加仓 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #72 | $3,426.5万 | 412.3万股 | $4,123.0万 | 389.0万股 | +23.4万股+6.01% | 加仓 |
| D.E.肖D. E. Shaw & Co., Inc. |
| 0.01% | 0.02% | #38 | $2,904.5万 | 349.5万股 | $3,856.9万 | 363.9万股 | -14.3万股-3.94% | 减仓 |
| PFIZER INC |
| 16.24% | 14.63% | #1 | $2,766.3万 | 345.8万股 | $3,492.4万 | 345.8万股 | 00.00% | 持仓不变 |
| 停战资本ARMISTICE CAPITAL, LLC |
| 0.28% | 0.37% | #7 | $2,323.5万 | 279.6万股 | $2,096.7万 | 197.8万股 | +81.8万股+41.35% | 加仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #107 | $2,255.5万 | 271.4万股 | $2,850.7万 | 268.9万股 | +2.5万股+0.92% | 加仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| 0.02% | 0.02% | #37 | $2,138.5万 | 257.3万股 | $1,942.0万 | 183.2万股 | +74.1万股+40.46% | 加仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #104 | $1,825.6万 | 219.7万股 | $1,938.2万 | 182.8万股 | +36.8万股+20.15% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #92 | $1,385.8万 | 166.7万股 | $1,650.9万 | 155.7万股 | +11.0万股+7.07% | 加仓 |
| Qube研究科技Qube Research & Technologies Ltd |
| 0.01% | 0.01% | #42 | $1,323.2万 | 159.2万股 | $1,273.7万 | 120.2万股 | +39.1万股+32.51% | 加仓 |
| Jacobs Levy股票管理JACOBS LEVY EQUITY MANAGEMENT, INC |
| 0.04% | 0.06% | #25 | $1,173.9万 | 141.3万股 | $1,528.0万 | 144.2万股 | -2.9万股-2.00% | 减仓 |
| Federated HermesFEDERATED HERMES, INC. |
| 0.02% | 0.02% | #35 | $1,126.9万 | 135.6万股 | $1,209.2万 | 114.1万股 | +21.5万股+18.88% | 加仓 |
| Nextech Invest Ltd. |
| 0.43% | 0.4% | #5 | $898.2万 | 112.3万股 | $571.8万 | 53.9万股 | +58.3万股+108.14% | 加仓 |
| ACADIAN ASSET MANAGEMENT LLC |
| 0.01% | 0.01% | #46 | $705.0万 | 84.8万股 | $1,006.2万 | 95.0万股 | -10.1万股-10.68% | 减仓 |
| Hillsdale Investment Management Inc. |
| 0.14% | — | #9 | $624.0万 | 75.1万股 | $0 | 0股 | +75.1万股 | 新买入 |
| 普信集团PRICE T ROWE ASSOCIATES INC /MD/ |
| <0.01% | <0.01% | #100 | $605.1万 | 72.8万股 | $452.8万 | 42.7万股 | +30.1万股+70.49% | 加仓 |
| TCG Crossover 管理TCG Crossover Management, LLC |
| 0.14% | 0.72% | #10 | $587.6万 | 70.7万股 | $2,530.7万 | 238.7万股 | -168.0万股-70.38% | 减仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #96 | $563.2万 | 67.8万股 | $1,301.1万 | 122.7万股 | -55.0万股-44.78% | 减仓 |
| 维度基金顾问DIMENSIONAL FUND ADVISORS LP |
| <0.01% | <0.01% | #85 | $544.2万 | 65.5万股 | $514.7万 | 48.6万股 | +16.9万股+34.82% | 加仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #111 | $532.5万 | 64.1万股 | $802.3万 | 75.7万股 | -11.6万股-15.33% | 减仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #102 | $511.3万 | 61.5万股 | $552.2万 | 52.1万股 | +9.4万股+18.11% | 加仓 |
| AQR资本管理AQR CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #68 | $500.2万 | 60.2万股 | $302.2万 | 28.5万股 | +31.7万股+111.10% | 加仓 |
| 肯尼迪资本管理KENNEDY CAPITAL MANAGEMENT LLC |
| 0.09% | 0.12% | #13 | $489.7万 | 58.9万股 | $585.8万 | 55.3万股 | +3.7万股+6.62% | 加仓 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #69 | $477.0万 | 57.4万股 | $610.9万 | 57.6万股 | -2,341股-0.41% | 减仓 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #99 | $450.5万 | 54.2万股 | $556.7万 | 52.5万股 | +1.7万股+3.24% | 加仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #133 | $417.8万 | 50.3万股 | $1,416.2万 | 166.2万股 | -115.9万股-69.75% | 减仓 |
| 北欧投资管理NORDEA INVESTMENT MANAGEMENT AB |
| <0.01% | <0.01% | #56 | $398.6万 | 47.6万股 | $505.3万 | 47.5万股 | +1,693股+0.36% | 加仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #109 | $369.5万 | 44.5万股 | $72.3万 | 6.8万股 | +37.6万股+551.58% | 加仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #91 | $355.0万 | 42.7万股 | $437.4万 | 41.3万股 | +1.5万股+3.55% | 加仓 |
| Algert全球ALGERT GLOBAL LLC |
| 0.04% | 0.03% | #26 | $354.4万 | 42.6万股 | $190.3万 | 17.9万股 | +24.7万股+137.56% | 加仓 |
| 富兰克林资源FRANKLIN RESOURCES INC |
| <0.01% | <0.01% | #98 | $304.5万 | 36.6万股 | $229.8万 | 21.7万股 | +15.0万股+69.02% | 加仓 |
| 富达投资FMR LLC |
| <0.01% | <0.01% | #153 | $303.5万 | 36.5万股 | $93.5万 | 8.8万股 | +27.7万股+313.92% | 加仓 |
| Brummer Multi-Strategy AB |
| 11.43% | 12.58% | #2 | $302.2万 | 28.5万股 | $302.2万 | 28.5万股 | 00.00% | 持仓不变 |
| Ikarian Capital, LLC |
| 0.32% | 0.31% | #6 | $297.7万 | 35.8万股 | $379.8万 | 35.8万股 | 00.00% | 持仓不变 |
| Nantahala 资本管理Nantahala Capital Management, LLC |
| 0.08% | 0.12% | #15 | $249.3万 | 30.0万股 | $318.0万 | 30.0万股 | 00.00% | 持仓不变 |
| 跳跃金融Jump Financial, LLC |
| 0.02% | 0.02% | #33 | $246.1万 | 29.6万股 | $141.8万 | 13.4万股 | +16.2万股+121.32% | 加仓 |
| Arbiter Partners Capital Management LLC |
| 1.29% | — | #4 | $244.8万 | 29.5万股 | $0 | 0股 | +29.5万股 | 新买入 |
| 英仕曼集团Man Group plc |
| <0.01% | <0.01% | #54 | $212.8万 | 25.6万股 | $96.4万 | 9.1万股 | +16.5万股+181.53% | 加仓 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| <0.01% | <0.01% | #120 | $211.9万 | 25.5万股 | $250.9万 | 23.7万股 | +1.8万股+7.72% | 加仓 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #152 | $210.2万 | 25.3万股 | $123.8万 | 11.7万股 | +13.6万股+116.56% | 加仓 |
| 景顺Invesco Ltd. |
| <0.01% | <0.01% | #145 | $206.0万 | 24.8万股 | $335.7万 | 31.7万股 | -6.9万股-21.71% | 减仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | — | #63 | $179.0万 | 21.5万股 | $0 | 0股 | +21.5万股 | 新买入 |
| SquarepointSquarepoint Ops LLC |
| <0.01% | <0.01% | #66 | $167.7万 | 20.2万股 | $24.9万 | 2.3万股 | +17.8万股+760.28% | 加仓 |
| 阿默普莱斯金融AMERIPRISE FINANCIAL INC |
| <0.01% | <0.01% | #122 | $154.0万 | 18.5万股 | $196.6万 | 18.5万股 | -148股-0.08% | 减仓 |
| 野村资产管理国际NOMURA ASSET MANAGEMENT INTERNATIONAL INC. |
| <0.01% | <0.01% | #65 | $149.6万 | 18.0万股 | $190.8万 | 18.0万股 | 00.00% | 持仓不变 |
| Rangeley Capital, LLC |
| 1.39% | 2.31% | #3 | $145.9万 | 17.6万股 | $237.4万 | 22.4万股 | -4.8万股-21.61% | 减仓 |
| Connor Clark & Lunn投资管理Connor, Clark & Lunn Investment Management Ltd. |
| <0.01% | <0.01% | #60 | $138.8万 | 16.7万股 | $139.9万 | 13.2万股 | +3.5万股+26.58% | 加仓 |
| 罗素投资集团Russell Investments Group, Ltd. |
| <0.01% | <0.01% | #83 | $138.1万 | 16.6万股 | $145.4万 | 13.7万股 | +2.9万股+21.17% | 加仓 |
| 萨斯奎汉纳组合策略Susquehanna Portfolio Strategies, LLC |
| 0.02% | 0.05% | #32 | $131.5万 | 15.8万股 | $319.3万 | 30.1万股 | -14.3万股-47.46% | 减仓 |
| DEUTSCHE 银行 AG\DEUTSCHE BANK AG\ |
| <0.01% | <0.01% | #118 | $125.6万 | 15.1万股 | $156.4万 | 14.8万股 | +3,645股+2.47% | 加仓 |
