| Sands Capital Alternatives, LLC |
| 18.68% | — | #2 | $1.15亿 | 423.1万股 | $0 | 0股 | +423.1万股 | 新买入 |
| Samsara BioCapital, LLC |
| 5.52% | — | #3 | $6,719.2万 | 248.0万股 | $0 | 0股 | +248.0万股 | 新买入 |
| 普信投资管理T. Rowe Price Investment Management, Inc. |
| 0.04% | — | #18 | $5,966.8万 | 220.3万股 | $0 | 0股 | +220.3万股 | 新买入 |
| ARK投资管理ARK Investment Management LLC |
| 0.24% | — | #9 | $3,722.1万 | 137.4万股 | $0 | 0股 | +137.4万股 | 新买入 |
| BRAIDWELL LP |
| 1.09% | — | #5 | $2,936.5万 | 108.4万股 | $0 | 0股 | +108.4万股 | 新买入 |
| 联博ALLIANCEBERNSTEIN L.P. |
| 0.01% | — | #30 | $2,717.3万 | 100.3万股 | $0 | 0股 | +100.3万股 | 新买入 |
| 高瓴资本Hillhouse Capital Advisors, Ltd. |
| 3.11% | — | #4 | $2,591.1万 | 95.6万股 | $0 | 0股 | +95.6万股 | 新买入 |
| 贝莱德BlackRock, Inc. |
| <0.01% | — | #53 | $2,469.1万 | 91.1万股 | $0 | 0股 | +91.1万股 | 新买入 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| 0.01% | — | #31 | $2,345.4万 | 86.6万股 | $0 | 0股 | +86.6万股 | 新买入 |
| 富达投资FMR LLC |
| <0.01% | — | #43 | $2,246.9万 | 82.9万股 | $0 | 0股 | +82.9万股 | 新买入 |
| PURA VIDA INVESTMENTS, LLC |
| 55.35% | — | #1 | $2,047.8万 | 75.6万股 | $0 | 0股 | +75.6万股 | 新买入 |
| EMERALD ADVISERS, LLC |
| 0.41% | — | #7 | $1,753.2万 | 64.7万股 | $0 | 0股 | +64.7万股 | 新买入 |
| 工匠合伙人Artisan Partners Limited Partnership |
| 0.03% | — | #20 | $1,662.6万 | 61.4万股 | $0 | 0股 | +61.4万股 | 新买入 |
| Deerfield管理DEERFIELD MANAGEMENT COMPANY, L.P. |
| 0.17% | — | #10 | $1,625.4万 | 60.0万股 | $0 | 0股 | +60.0万股 | 新买入 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | — | #58 | $1,255.3万 | 46.3万股 | $0 | 0股 | +46.3万股 | 新买入 |
| 法伦资本FARALLON CAPITAL MANAGEMENT, L.L.C. |
| 0.06% | — | #17 | $1,254.0万 | 46.3万股 | $0 | 0股 | +46.3万股 | 新买入 |
| 惠灵顿管理集团WELLINGTON MANAGEMENT GROUP LLP |
| <0.01% | — | #39 | $1,240.7万 | 45.8万股 | $0 | 0股 | +45.8万股 | 新买入 |
| EMERALD MUTUAL FUND ADVISERS 信托EMERALD MUTUAL FUND ADVISERS TRUST |
| 0.4% | — | #8 | $1,143.5万 | 42.2万股 | $0 | 0股 | +42.2万股 | 新买入 |
| 阿默普莱斯金融AMERIPRISE FINANCIAL INC |
| <0.01% | — | #38 | $1,135.0万 | 41.9万股 | $0 | 0股 | +41.9万股 | 新买入 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | — | #50 | $894.5万 | 33.0万股 | $0 | 0股 | +33.0万股 | 新买入 |
| Woodline合伙人Woodline Partners LP |
| 0.02% | — | #22 | $659.2万 | 24.3万股 | $0 | 0股 | +24.3万股 | 新买入 |
| 纽约州共同退休基金NEW YORK STATE COMMON RETIREMENT FUND |
| 0.01% | — | #37 | $543.9万 | 20.1万股 | $0 | 0股 | +20.1万股 | 新买入 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | — | #48 | $487.6万 | 18.0万股 | $0 | 0股 | +18.0万股 | 新买入 |
| LORD, ABBETT & CO. LLC |
| 0.01% | — | #28 | $481.0万 | 17.8万股 | $0 | 0股 | +17.8万股 | 新买入 |
| LMR合伙人LMR Partners LLP |
| 0.02% | — | #26 | $474.1万 | 17.5万股 | $0 | 0股 | +17.5万股 | 新买入 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | — | #52 | $433.5万 | 16.0万股 | $0 | 0股 | +16.0万股 | 新买入 |
| 吉萨洛资本管理Ghisallo Capital Management LLC |
| 0.02% | — | #21 | $406.4万 | 15.0万股 | $0 | 0股 | +15.0万股 | 新买入 |
| SEVEN GRAND MANAGERS, LLC |
| 0.16% | — | #12 | $406.4万 | 15.0万股 | $0 | 0股 | +15.0万股 | 新买入 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | — | #51 | $311.4万 | 11.5万股 | $0 | 0股 | +11.5万股 | 新买入 |
| Alyeska投资集团Alyeska Investment Group, L.P. |
| 0.01% | — | #32 | $307.2万 | 11.3万股 | $0 | 0股 | +11.3万股 | 新买入 |
| Avidity Partners Management LP |
| 0.48% | — | #6 | $298.0万 | 11.0万股 | $0 | 0股 | +11.0万股 | 新买入 |
| ExodusPoint资本ExodusPoint Capital Management, LP |
| 0.02% | — | #27 | $272.8万 | 10.1万股 | $0 | 0股 | +10.1万股 | 新买入 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | — | #54 | $271.2万 | 10.0万股 | $0 | 0股 | +10.0万股 | 新买入 |
| Burkehill Global 管理Burkehill Global Management, LP |
| 0.1% | — | #13 | $270.9万 | 10.0万股 | $0 | 0股 | +10.0万股 | 新买入 |
| 摩根大通JPMORGAN CHASE & CO |
| <0.01% | — | #67 | $257.3万 | 9.3万股 | $0 | 0股 | +9.3万股 | 新买入 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | — | #69 | $246.7万 | 9.1万股 | $0 | 0股 | +9.1万股 | 新买入 |
| 瑞银集团UBS Group AG |
| <0.01% | — | #56 | $235.0万 | 8.7万股 | $0 | 0股 | +8.7万股 | 新买入 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | — | #49 | $222.9万 | 8.2万股 | $0 | 0股 | +8.2万股 | 新买入 |
| Freestone Grove合伙人Freestone Grove Partners LP |
| 0.01% | — | #29 | $162.5万 | 6.0万股 | $0 | 0股 | +6.0万股 | 新买入 |
| 索罗斯基金管理SOROS FUND MANAGEMENT LLC |
| 0.02% | — | #23 | $162.5万 | 6.0万股 | $0 | 0股 | +6.0万股 | 新买入 |
| IEQ资本IEQ CAPITAL, LLC |
| 0.01% | — | #34 | $159.3万 | 5.9万股 | $0 | 0股 | +5.9万股 | 新买入 |
| 三井住友信托集团Sumitomo Mitsui Trust Group, Inc. |
| <0.01% | — | #44 | $152.9万 | 5.6万股 | $0 | 0股 | +5.6万股 | 新买入 |
| Amova资产管理Amova Asset Management Americas, Inc. |
| 0.02% | — | #24 | $151.1万 | 5.6万股 | $0 | 0股 | +5.6万股 | 新买入 |
| Bellevue 集团Bellevue Group AG |
| 0.03% | — | #19 | $151.0万 | 5.6万股 | $0 | 0股 | +5.6万股 | 新买入 |
| Point72资产管理Point72 Asset Management, L.P. |
| <0.01% | — | #40 | $140.3万 | 5.2万股 | $0 | 0股 | +5.2万股 | 新买入 |
| Shay Capital LLC |
| 0.07% | — | #15 | $108.4万 | 4.0万股 | $0 | 0股 | +4.0万股 | 新买入 |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd |
| 0.06% | — | #16 | $94.1万 | 3.5万股 | $0 | 0股 | +3.5万股 | 新买入 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| <0.01% | — | #66 | $88.1万 | 3.3万股 | $0 | 0股 | +3.3万股 | 新买入 |
| 道明资产管理TD ASSET MANAGEMENT INC |
| <0.01% | — | #47 | $72.4万 | 2.7万股 | $0 | 0股 | +2.7万股 | 新买入 |
| 韦斯资产管理Weiss Asset Management LP |
| 0.01% | — | #36 | $67.7万 | 2.5万股 | $0 | 0股 | +2.5万股 | 新买入 |
