| BAIN CAPITAL INVESTORS LLC |
| 12.01% | — | #4 | $5.78亿 | 2,625.6万股 | $0 | 0股 | +2,625.6万股 | 新买入 |
| Bain Capital Life Sciences Investors, LLC |
| 29.58% | — | #1 | $4.98亿 | 2,258.3万股 | $0 | 0股 | +2,258.3万股 | 新买入 |
| RTW投资RTW INVESTMENTS, LP |
| 2.03% | — | #6 | $2.37亿 | 1,077.7万股 | $0 | 0股 | +1,077.7万股 | 新买入 |
| 加拿大养老金计划投资委员会(CPPIB)CANADA PENSION PLAN INVESTMENT BOARD |
| 0.09% | — | #20 | $1.61亿 | 730.5万股 | $0 | 0股 | +730.5万股 | 新买入 |
| Atlas Venture Life Science Advisors, LLC |
| 12.93% | — | #3 | $1.14亿 | 517.1万股 | $0 | 0股 | +517.1万股 | 新买入 |
| 富达投资FMR LLC |
| <0.01% | — | #38 | $8,747.8万 | 397.1万股 | $0 | 0股 | +397.1万股 | 新买入 |
| 贝莱德BlackRock, Inc. |
| <0.01% | — | #55 | $8,654.7万 | 392.9万股 | $0 | 0股 | +392.9万股 | 新买入 |
| 普信集团PRICE T ROWE ASSOCIATES INC /MD/ |
| 0.01% | — | #34 | $7,786.3万 | 353.4万股 | $0 | 0股 | +353.4万股 | 新买入 |
| 城堡顾问CITADEL ADVISORS LLC |
| 0.01% | — | #33 | $7,139.5万 | 324.1万股 | $0 | 0股 | +324.1万股 | 新买入 |
| Adage资本合伙人ADAGE CAPITAL PARTNERS GP, L.L.C. |
| 0.1% | — | #19 | $7,067.9万 | 320.8万股 | $0 | 0股 | +320.8万股 | 新买入 |
| 惠灵顿管理集团WELLINGTON MANAGEMENT GROUP LLP |
| 0.01% | — | #28 | $6,430.8万 | 291.9万股 | $0 | 0股 | +291.9万股 | 新买入 |
| Royalty Pharma Sub-Manager, LLC |
| 22.36% | — | #2 | $5,409.2万 | 245.5万股 | $0 | 0股 | +245.5万股 | 新买入 |
| Siren, L.L.C. |
| 0.99% | — | #8 | $4,878.1万 | 221.4万股 | $0 | 0股 | +221.4万股 | 新买入 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | — | #64 | $3,731.8万 | 169.4万股 | $0 | 0股 | +169.4万股 | 新买入 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | — | #49 | $3,640.5万 | 165.3万股 | $0 | 0股 | +165.3万股 | 新买入 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | — | #54 | $2,496.8万 | 113.3万股 | $0 | 0股 | +113.3万股 | 新买入 |
| 法伦资本FARALLON CAPITAL MANAGEMENT, L.L.C. |
| 0.11% | — | #17 | $2,423.3万 | 110.0万股 | $0 | 0股 | +110.0万股 | 新买入 |
| Frazier Life Sciences 管理Frazier Life Sciences Management, L.P. |
| 0.53% | — | #10 | $2,423.3万 | 110.0万股 | $0 | 0股 | +110.0万股 | 新买入 |
| Trails Edge Capital Partners, LP |
| 3.44% | — | #5 | $2,169.5万 | 98.5万股 | $0 | 0股 | +98.5万股 | 新买入 |
| 瑞银集团UBS Group AG |
| <0.01% | — | #43 | $2,142.8万 | 97.3万股 | $0 | 0股 | +97.3万股 | 新买入 |
| 木星资产管理Jupiter Topco LLC |
| 0.01% | — | #32 | $2,134.4万 | 97.1万股 | $0 | 0股 | +97.1万股 | 新买入 |
| 阿默普莱斯金融AMERIPRISE FINANCIAL INC |
| <0.01% | — | #39 | $1,809.4万 | 82.1万股 | $0 | 0股 | +82.1万股 | 新买入 |
| 深轨资本Deep Track Capital, LP |
| 0.22% | — | #13 | $1,542.1万 | 70.0万股 | $0 | 0股 | +70.0万股 | 新买入 |
| 暮色资产管理EVENTIDE ASSET MANAGEMENT, LLC |
| 0.18% | — | #14 | $1,358.6万 | 61.7万股 | $0 | 0股 | +61.7万股 | 新买入 |
| Vestal Point 资本Vestal Point Capital, LP |
| 0.3% | — | #11 | $1,266.7万 | 57.5万股 | $0 | 0股 | +57.5万股 | 新买入 |
| Cormorant Asset Management, LP |
| 0.62% | — | #9 | $1,211.7万 | 55.0万股 | $0 | 0股 | +55.0万股 | 新买入 |
| Catalio Capital Management, LP |
| 1.94% | — | #7 | $1,032.7万 | 46.9万股 | $0 | 0股 | +46.9万股 | 新买入 |
| Federated HermesFEDERATED HERMES, INC. |
| 0.01% | — | #25 | $956.3万 | 43.4万股 | $0 | 0股 | +43.4万股 | 新买入 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | — | #63 | $927.5万 | 42.1万股 | $0 | 0股 | +42.1万股 | 新买入 |
| 富兰克林资源FRANKLIN RESOURCES INC |
| <0.01% | — | #47 | $881.3万 | 40.0万股 | $0 | 0股 | +40.0万股 | 新买入 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | — | #58 | $799.5万 | 36.3万股 | $0 | 0股 | +36.3万股 | 新买入 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | — | #61 | $780.8万 | 35.4万股 | $0 | 0股 | +35.4万股 | 新买入 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | — | #53 | $639.2万 | 29.0万股 | $0 | 0股 | +29.0万股 | 新买入 |
| SEVEN GRAND MANAGERS, LLC |
| 0.16% | — | #15 | $385.5万 | 17.5万股 | $0 | 0股 | +17.5万股 | 新买入 |
| Balyasny资产管理BALYASNY ASSET MANAGEMENT L.P. |
| <0.01% | — | #37 | $341.1万 | 15.5万股 | $0 | 0股 | +15.5万股 | 新买入 |
| Exchange Traded ConceptsEXCHANGE TRADED CONCEPTS, LLC |
| 0.02% | — | #23 | $336.0万 | 15.3万股 | $0 | 0股 | +15.3万股 | 新买入 |
| 宏利人寿MANUFACTURERS LIFE INSURANCE COMPANY, THE |
| <0.01% | — | #44 | $330.0万 | 15.0万股 | $0 | 0股 | +15.0万股 | 新买入 |
| 道明资产管理TD ASSET MANAGEMENT INC |
| <0.01% | — | #41 | $325.4万 | 14.8万股 | $0 | 0股 | +14.8万股 | 新买入 |
| 安本标准投资Aberdeen Group plc |
| <0.01% | — | #36 | $308.4万 | 14.0万股 | $0 | 0股 | +14.0万股 | 新买入 |
| Nantahala 资本管理Nantahala Capital Management, LLC |
| 0.1% | — | #18 | $308.4万 | 14.0万股 | $0 | 0股 | +14.0万股 | 新买入 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| <0.01% | — | #70 | $304.9万 | 13.8万股 | $0 | 0股 | +13.8万股 | 新买入 |
| ALPS顾问ALPS ADVISORS INC |
| 0.01% | — | #26 | $288.6万 | 13.1万股 | $0 | 0股 | +13.1万股 | 新买入 |
| 纽文Nuveen, LLC |
| <0.01% | — | #71 | $195.6万 | 8.9万股 | $0 | 0股 | +8.9万股 | 新买入 |
| Avidity Partners Management LP |
| 0.28% | — | #12 | $176.2万 | 8.0万股 | $0 | 0股 | +8.0万股 | 新买入 |
| 吉萨洛资本管理Ghisallo Capital Management LLC |
| 0.01% | — | #31 | $165.2万 | 7.5万股 | $0 | 0股 | +7.5万股 | 新买入 |
| Rock Springs Capital Management LP |
| 0.07% | — | #21 | $143.2万 | 6.5万股 | $0 | 0股 | +6.5万股 | 新买入 |
| 联博ALLIANCEBERNSTEIN L.P. |
| <0.01% | — | #72 | $134.6万 | 6.1万股 | $0 | 0股 | +6.1万股 | 新买入 |
| RhumbLine顾问RHUMBLINE ADVISERS |
| <0.01% | — | #59 | $128.6万 | 5.8万股 | $0 | 0股 | +5.8万股 | 新买入 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | — | #86 | $127.3万 | 5.8万股 | $0 | 0股 | +5.8万股 | 新买入 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| <0.01% | — | #83 | $124.5万 | 5.7万股 | $0 | 0股 | +5.7万股 | 新买入 |
