| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #82 | $1.37亿 | 3,213.3万股 | $7,007.2万 | 2,860.1万股 | +353.2万股+12.35% | 加仓 |
| Rubric资本管理Rubric Capital Management LP |
| 0.7% | 0.09% | #4 | $7,668.0万 | 1,800.0万股 | $887.0万 | 362.0万股 | +1,438.0万股+397.18% | 加仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #81 | $6,890.1万 | 1,617.4万股 | $4,577.5万 | 1,868.3万股 | -250.9万股-13.43% | 减仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #112 | $5,610.2万 | 1,316.9万股 | $3,158.3万 | 1,289.1万股 | +27.8万股+2.16% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #88 | $3,386.2万 | 794.7万股 | $1,839.1万 | 750.5万股 | +44.2万股+5.89% | 加仓 |
| 惠灵顿管理集团WELLINGTON MANAGEMENT GROUP LLP |
| 0.01% | <0.01% | #47 | $3,341.9万 | 784.5万股 | $804.4万 | 328.3万股 | +456.2万股+138.94% | 加仓 |
| Frazier Life Sciences 管理Frazier Life Sciences Management, L.P. |
| 0.61% | 0.37% | #5 | $2,811.6万 | 660.0万股 | $1,445.5万 | 590.0万股 | +70.0万股+11.86% | 加仓 |
| 深轨资本Deep Track Capital, LP |
| 0.37% | — | #9 | $2,556.0万 | 600.0万股 | $0 | 0股 | +600.0万股 | 新买入 |
| 180 WEALTH ADVISORS, LLC |
| 2.12% | 1.2% | #3 | $2,112.9万 | 496.0万股 | $1,051.5万 | 429.2万股 | +66.8万股+15.57% | 加仓 |
| 富达投资FMR LLC |
| <0.01% | <0.01% | #138 | $1,747.0万 | 410.1万股 | $852.8万 | 348.1万股 | +62.0万股+17.81% | 加仓 |
| TSP Capital Management Group, LLC |
| 4.05% | 2% | #1 | $1,692.4万 | 397.3万股 | $819.3万 | 334.4万股 | +62.9万股+18.80% | 加仓 |
| AQR资本管理AQR CAPITAL MANAGEMENT LLC |
| 0.01% | <0.01% | #48 | $1,622.6万 | 380.9万股 | $111.0万 | 45.3万股 | +335.6万股+740.83% | 加仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #135 | $1,480.3万 | 347.5万股 | $2,067.7万 | 385.0万股 | -37.6万股-9.75% | 减仓 |
| BRAIDWELL LP |
| 0.54% | — | #7 | $1,473.3万 | 345.8万股 | $0 | 0股 | +345.8万股 | 新买入 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #156 | $1,278.9万 | 300.2万股 | $777.1万 | 317.2万股 | -17.0万股-5.35% | 减仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #105 | $1,230.0万 | 288.7万股 | $655.6万 | 267.6万股 | +21.1万股+7.90% | 加仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #99 | $1,229.5万 | 288.6万股 | $2,022.6万 | 825.5万股 | -536.9万股-65.04% | 减仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| 0.01% | 0.01% | #38 | $1,147.5万 | 269.4万股 | $709.5万 | 289.6万股 | -20.2万股-6.98% | 减仓 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #102 | $1,107.1万 | 259.9万股 | $624.5万 | 254.9万股 | +5.0万股+1.95% | 加仓 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #146 | $1,007.4万 | 236.5万股 | $829.0万 | 338.4万股 | -101.9万股-30.11% | 减仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #80 | $935.8万 | 219.7万股 | $523.7万 | 213.8万股 | +5.9万股+2.77% | 加仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #131 | $917.8万 | 215.4万股 | $720.9万 | 294.2万股 | -78.8万股-26.78% | 减仓 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #154 | $767.0万 | 180.1万股 | $427.1万 | 174.3万股 | +5.7万股+3.28% | 加仓 |
| 富国银行WELLS FARGO & COMPANY/MN |
| <0.01% | <0.01% | #118 | $629.0万 | 147.6万股 | $210.8万 | 86.0万股 | +61.6万股+71.58% | 加仓 |
| Caption管理Caption Management, LLC |
| 0.03% | 0.02% | #21 | $567.4万 | 133.2万股 | $345.5万 | 141.0万股 | -7.8万股-5.53% | 减仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #147 | $564.6万 | 132.5万股 | $398.4万 | 162.6万股 | -30.1万股-18.50% | 减仓 |
| 维度基金顾问DIMENSIONAL FUND ADVISORS LP |
| <0.01% | <0.01% | #127 | $466.1万 | 109.4万股 | $1,213.4万 | 495.3万股 | -385.9万股-77.91% | 减仓 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| <0.01% | <0.01% | #149 | $382.7万 | 89.8万股 | $207.2万 | 84.6万股 | +5.3万股+6.26% | 加仓 |
| J. Goldman & Co LP |
| 0.09% | — | #14 | $347.9万 | 81.7万股 | $0 | 0股 | +81.7万股 | 新买入 |
| SCOPIA CAPITAL MANAGEMENT LP |
| 2.65% | 1.17% | #2 | $296.1万 | 69.5万股 | $170.3万 | 69.5万股 | 00.00% | 持仓不变 |
| Balyasny资产管理BALYASNY ASSET MANAGEMENT L.P. |
| <0.01% | <0.01% | #57 | $291.4万 | 68.4万股 | $50.6万 | 20.7万股 | +47.8万股+231.27% | 加仓 |
| 胜利资本管理VICTORY CAPITAL MANAGEMENT INC |
| <0.01% | <0.01% | #100 | $277.1万 | 65.1万股 | $301.9万 | 123.2万股 | -58.2万股-47.20% | 减仓 |
| 纽文Nuveen, LLC |
| <0.01% | <0.01% | #145 | $270.8万 | 63.6万股 | $530.4万 | 216.5万股 | -152.9万股-70.63% | 减仓 |
| DELTEC ASSET MANAGEMENT LLC |
| 0.4% | 0.19% | #8 | $267.5万 | 62.8万股 | $104.9万 | 42.8万股 | +20.0万股+46.73% | 加仓 |
| 木星资产管理Jupiter Topco LLC |
| <0.01% | — | #117 | $252.2万 | 59.2万股 | $0 | 0股 | +59.2万股 | 新买入 |
| 瑞士央行Swiss National Bank |
| <0.01% | <0.01% | #109 | $250.2万 | 58.7万股 | $140.8万 | 57.5万股 | +1.3万股+2.21% | 加仓 |
| 瑞银资产管理(美洲)UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
| <0.01% | <0.01% | #173 | $228.8万 | 53.7万股 | $302.0万 | 123.3万股 | -69.6万股-56.42% | 减仓 |
| 威斯康星州投资委员会STATE OF WISCONSIN INVESTMENT BOARD |
| <0.01% | <0.01% | #53 | $217.7万 | 51.1万股 | $39.0万 | 15.9万股 | +35.2万股+220.88% | 加仓 |
| Jacobs Levy股票管理JACOBS LEVY EQUITY MANAGEMENT, INC |
| 0.01% | <0.01% | #40 | $210.7万 | 49.4万股 | $10.6万 | 4.3万股 | +45.1万股+1,038.28% | 加仓 |
| 1492 Capital Management LLC |
| 0.61% | 0.51% | #6 | $205.2万 | 48.2万股 | $134.7万 | 55.0万股 | -6.8万股-12.38% | 减仓 |
| MarinerMariner, LLC |
| <0.01% | <0.01% | #79 | $202.0万 | 47.4万股 | $51.8万 | 21.1万股 | +26.3万股+124.25% | 加仓 |
| 普信集团PRICE T ROWE ASSOCIATES INC /MD/ |
| <0.01% | <0.01% | #196 | $200.9万 | 47.2万股 | $93.1万 | 38.0万股 | +9.2万股+24.22% | 加仓 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | 0.01% | #150 | $183.7万 | 43.1万股 | $1,565.8万 | 639.1万股 | -596.0万股-93.25% | 减仓 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #210 | $180.6万 | 42.4万股 | $40.4万 | 16.5万股 | +25.9万股+157.44% | 加仓 |
| Schonfeld战略顾问Schonfeld Strategic Advisors LLC |
| 0.01% | <0.01% | #45 | $177.4万 | 41.6万股 | $9.7万 | 4.0万股 | +37.7万股+951.43% | 加仓 |
| SquarepointSquarepoint Ops LLC |
| <0.01% | — | #83 | $176.0万 | 41.3万股 | $0 | 0股 | +41.3万股 | 新买入 |
| 杰富瑞金融集团Jefferies Financial Group Inc. |
| 0.01% | 0.01% | #32 | $169.4万 | 39.8万股 | $169.5万 | 69.2万股 | -29.4万股-42.50% | 减仓 |
| ExodusPoint资本ExodusPoint Capital Management, LP |
| 0.01% | — | #33 | $166.6万 | 39.1万股 | $0 | 0股 | +39.1万股 | 新买入 |
| 信安金融集团PRINCIPAL FINANCIAL GROUP INC |
| <0.01% | <0.01% | #130 | $163.0万 | 38.3万股 | $86.3万 | 35.2万股 | +3.0万股+8.59% | 加仓 |
| 英仕曼集团Man Group plc |
| <0.01% | <0.01% | #70 | $162.4万 | 38.1万股 | $116.3万 | 47.5万股 | -9.3万股-19.68% | 减仓 |
