| 深轨资本Deep Track Capital, LP |
| 2.5% | 1.1% | #14 | $1.72亿 | 1,216.1万股 | $6,725.3万 | 1,216.1万股 | 00.00% | 持仓不变 |
| RTW投资RTW INVESTMENTS, LP |
| 1.29% | 0.59% | #16 | $1.51亿 | 1,070.1万股 | $5,879.7万 | 1,063.2万股 | +6.9万股+0.65% | 加仓 |
| BIT Capital GmbH |
| 2.66% | 0.93% | #12 | $8,983.5万 | 634.9万股 | $1,930.7万 | 349.1万股 | +285.8万股+81.85% | 加仓 |
| TANG CAPITAL MANAGEMENT LLC |
| 3.21% | 1.12% | #10 | $7,075.0万 | 500.0万股 | $2,213.2万 | 400.2万股 | +99.8万股+24.93% | 加仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| 0.05% | 0.01% | #67 | $6,325.7万 | 447.0万股 | $1,428.7万 | 258.3万股 | +188.7万股+73.04% | 加仓 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| 0.05% | 0.02% | #63 | $6,125.1万 | 432.9万股 | $2,233.2万 | 403.8万股 | +29.0万股+7.19% | 加仓 |
| ARK投资管理ARK Investment Management LLC |
| 0.32% | 0.14% | #30 | $4,884.5万 | 345.2万股 | $1,825.5万 | 330.1万股 | +15.1万股+4.57% | 加仓 |
| Caption管理Caption Management, LLC |
| 0.19% | 0.12% | #38 | $4,119.4万 | 291.1万股 | $1,996.5万 | 361.0万股 | -69.9万股-19.36% | 减仓 |
| Point72资产管理Point72 Asset Management, L.P. |
| 0.04% | <0.01% | #69 | $3,708.5万 | 262.1万股 | $13.1万 | 2.4万股 | +259.7万股+11,005.42% | 加仓 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #113 | $3,493.7万 | 246.9万股 | $1,873.5万 | 338.8万股 | -91.9万股-27.12% | 减仓 |
| Logos Global Management LP |
| 1.37% | — | #15 | $3,183.8万 | 225.0万股 | $0 | 0股 | +225.0万股 | 新买入 |
| Eagle Health Investments LP |
| 4.83% | 1.99% | #5 | $2,915.5万 | 206.0万股 | $1,139.4万 | 206.0万股 | 00.00% | 持仓不变 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #125 | $2,857.4万 | 201.9万股 | $17.9万 | 3.2万股 | +198.7万股+6,145.66% | 加仓 |
| DAFNA Capital Management LLC |
| 5.43% | 3.04% | #3 | $2,846.9万 | 201.2万股 | $1,337.6万 | 241.9万股 | -40.7万股-16.82% | 减仓 |
| NEXTBio Capital Management LP |
| 11.56% | 5.19% | #1 | $2,512.7万 | 177.6万股 | $1,117.8万 | 202.1万股 | -24.6万股-12.15% | 减仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #111 | $2,448.2万 | 173.0万股 | $332.1万 | 60.1万股 | +113.0万股+188.08% | 加仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #114 | $2,097.7万 | 148.2万股 | $1,025.9万 | 185.5万股 | -37.3万股-20.09% | 减仓 |
| Aisling Capital Management LP |
| 4.3% | 1.66% | #7 | $2,026.8万 | 143.2万股 | $792.1万 | 143.2万股 | 00.00% | 持仓不变 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| 0.03% | 0.01% | #80 | $2,026.1万 | 143.2万股 | $478.5万 | 86.5万股 | +56.7万股+65.47% | 加仓 |
| 康得利安资管Candriam S.C.A. |
| 0.08% | — | #57 | $1,801.4万 | 127.4万股 | $0 | 0股 | +127.4万股 | 新买入 |
| Woodline合伙人Woodline Partners LP |
| 0.05% | <0.01% | #64 | $1,536.7万 | 108.6万股 | $97.0万 | 17.5万股 | +91.1万股+519.02% | 加仓 |
| 杰富瑞金融集团Jefferies Financial Group Inc. |
| 0.09% | 0.06% | #52 | $1,407.1万 | 99.4万股 | $811.5万 | 146.7万股 | -47.3万股-32.23% | 减仓 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #179 | $1,309.4万 | 92.5万股 | $377.8万 | 68.3万股 | +24.2万股+35.44% | 加仓 |
| Trexquant投资Trexquant Investment LP |
| 0.07% | 0.01% | #58 | $1,217.1万 | 86.0万股 | $171.0万 | 30.9万股 | +55.1万股+178.11% | 加仓 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #140 | $1,209.7万 | 85.5万股 | $268.3万 | 48.5万股 | +37.0万股+76.19% | 加仓 |
| Kalehua Capital Management LLC |
| 8.31% | 3.21% | #2 | $1,159.9万 | 82.0万股 | $453.3万 | 82.0万股 | 00.00% | 持仓不变 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | 0.01% | #106 | $1,090.9万 | 77.1万股 | $1,735.6万 | 313.9万股 | -236.8万股-75.43% | 减仓 |
| Axxion S.A. |
| 0.73% | — | #21 | $1,029.5万 | 72.8万股 | $0 | 0股 | +72.8万股 | 新买入 |
| Creek Drive Management Group LLC |
| 4.75% | 1.04% | #6 | $979.2万 | 69.2万股 | $456.2万 | 82.5万股 | -13.3万股-16.12% | 减仓 |
| Eversept Partners, LP |
| 0.49% | 0.2% | #26 | $952.0万 | 67.3万股 | $374.9万 | 67.8万股 | -5,099股-0.75% | 减仓 |
| Squadron Capital Management LLC |
| 2.66% | — | #13 | $856.1万 | 60.5万股 | $0 | 0股 | +60.5万股 | 新买入 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #164 | $841.8万 | 59.5万股 | $590.4万 | 103.0万股 | -43.5万股-42.26% | 减仓 |
| Propel Bio Management, LLC |
| 4.24% | 2.6% | #9 | $810.9万 | 57.3万股 | $411.8万 | 74.2万股 | -16.9万股-22.77% | 减仓 |
| Occam Crest Management LP |
| 4.25% | — | #8 | $773.9万 | 71.0万股 | $0 | 0股 | +71.0万股 | 新买入 |
| Walleye资本Walleye Capital LLC |
| 0.03% | 0.01% | #81 | $729.0万 | 51.5万股 | $216.5万 | 39.2万股 | +12.4万股+31.57% | 加仓 |
| SILVERARC CAPITAL MANAGEMENT, LLC |
| 0.74% | 0.17% | #20 | $712.3万 | 50.3万股 | $165.9万 | 30.0万股 | +20.3万股+67.79% | 加仓 |
| Qube研究科技Qube Research & Technologies Ltd |
| 0.01% | 0.01% | #96 | $707.0万 | 50.0万股 | $524.6万 | 94.9万股 | -44.9万股-47.32% | 减仓 |
| Ensign Peak顾问Ensign Peak Advisors, Inc |
| 0.01% | <0.01% | #91 | $671.6万 | 47.5万股 | $21.7万 | 3.9万股 | +43.5万股+1,110.08% | 加仓 |
| Blue Owl Capital Holdings LP |
| 0.93% | 1.38% | #19 | $636.8万 | 45.0万股 | $513.4万 | 180.5万股 | -135.5万股-75.06% | 减仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #160 | $612.5万 | 43.3万股 | $228.4万 | 41.3万股 | +2.0万股+4.82% | 加仓 |
| AdvisorShares Investments LLC |
| 0.72% | 0.25% | #22 | $596.2万 | 42.1万股 | $136.4万 | 24.7万股 | +17.5万股+70.77% | 加仓 |
| Hennion & Walsh Asset Management, Inc. |
| 0.17% | 0.09% | #42 | $591.2万 | 41.8万股 | $269.7万 | 48.8万股 | -7.0万股-14.32% | 减仓 |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. |
| 0.35% | 0.02% | #28 | $543.9万 | 38.4万股 | $37.9万 | 6.8万股 | +31.6万股+461.22% | 加仓 |
| HighVista Strategies LLC |
| 1.2% | 0.56% | #17 | $525.1万 | 37.1万股 | $201.5万 | 36.4万股 | +6,760股+1.86% | 加仓 |
| 英国法通集团Legal & General Group Plc |
| <0.01% | <0.01% | #143 | $470.0万 | 33.2万股 | $127.4万 | 23.1万股 | +10.1万股+43.57% | 加仓 |
| 三井住友信托集团Sumitomo Mitsui Trust Group, Inc. |
| <0.01% | <0.01% | #115 | $457.3万 | 32.3万股 | $204.0万 | 36.9万股 | -4.6万股-12.37% | 减仓 |
| Amova资产管理Amova Asset Management Americas, Inc. |
| 0.06% | 0.03% | #61 | $451.7万 | 31.9万股 | $202.9万 | 36.9万股 | -4.9万股-13.38% | 减仓 |
| Affinity Asset Advisors, LLC |
| 0.19% | 0.32% | #37 | $426.2万 | 30.1万股 | $613.0万 | 110.8万股 | -80.7万股-72.83% | 减仓 |
| Adage资本合伙人ADAGE CAPITAL PARTNERS GP, L.L.C. |
| 0.01% | <0.01% | #97 | $424.5万 | 30.0万股 | $165.9万 | 30.0万股 | 00.00% | 持仓不变 |
| SEVEN GRAND MANAGERS, LLC |
| 0.17% | 0.11% | #41 | $424.5万 | 30.0万股 | $165.9万 | 30.0万股 | 00.00% | 持仓不变 |
